Neeraj Kumari

Ms. Neeraj Kumari

shoolini university, Solan, India
orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
30 June 2021 in Antioxidants
Verified
Journal Article
Open access
PDF file
Manoj KumarManoj Kumar
Manoj Kumar
Suraj PrakashSuraj Prakash
Suraj Prakash
R.Radha ..
Radha ..
NKNeeraj Kumari
Neeraj Kumari
APAshok Pundir
Ashok Pundir
Mohamed MekhemarMohamed Mekhemar
Mohamed Mekhemar
Plant-derived phytochemicals have been touted as viable substitutes in a variety of diseases. All over the world, dentists have turned to natural remedies for dental cure due to the negative possessions of certain antibacterial mediators used in dentistry. Antimicrobial and other drugs are currently in use, but they show some side effects. Since ancient times, antioxidant EOs have been used for different ailments and have grown in popularity over time. Several in vitro, in vivo, and clinical trials have shown the safety and effectiveness of antioxidant essential oils (EOs) in oral health obtained from medicinal plants. The current review of literature provides a summary of secondary metabolites, more specifically EOs from 20 most commonly used medicinal plants and their applications in maintaining oral health. Dental caries and periodontal diseases are the most common and preventable global infectious diseases, with diseases of the oral cavity being considered major diseases affecting a person’s health. Several clinical studies have shown a connection between oral diseases and oral microbiota. This review discusses the role of antioxidant secondary metabolites in inhibiting the growth of oral pathogens and reducing the formation of dental plaque, and as well as reducing the symptoms of oral diseases. This review article contributes a basic outline of essential oils and their healing actions.

Verified
Journal Article
Open access
PDF file
NSNiharika Sharma
Niharika Sharma
R.Radha ..
Radha ..
Manoj KumarManoj Kumar
Manoj Kumar
Baohong ZhangBaohong Zhang
Baohong Zhang
NKNeeraj Kumari
Neeraj Kumari
Jose Manuel LorenzoJose Manuel Lorenzo
Jose Manuel Lorenzo
Aegle marmelos (L.) Correa (Bael) fruit, a member of the Rutaceae family, is a major cultivated fruit plant in tropical and subtropical regions in countries of southeast Asia. Bael fruit has been a major topic for studies in recent years mainly due to its high nutritional (carbohydrates, proteins, minerals, and vitamins) value and presence of various phytochemicals, which attributed to its high medicinal value. These phytochemicals include various compounds, e.g., alkaloids, flavonoids, and phenolic acids (protocatechuic acid, gallic, and ellagic acid). The fruit extract of bael has been also an important study area for its pharmacological activities, including antidiarrheal, antioxidant, antidiabetic, hepatoprotective, radioprotective, anticancer, antiulcer properties. The current review mainly highlighted the nutritional and pharmacological activities of bael fruit. The nutritional profile and phytochemical profile were discussed in the review, along with their concentration in the fruit. Moreover, the experiments carried out in vivo and in vitro of bael fruit extracts with respect to their pharmacological activities were also discussed in the article. The recent literature based on nutritional and pharmacological values of bael fruit showed its high potential as a food and pharmaceutical product. Despite having high nutritional and pharmacological value, research related to molecular mechanisms of bael fruit is still limited, and clinical trials are needed to ensure its safety as a product in the food and pharma industries.

14 November 2022 in Plants
Verified
Journal Article
Open access
PDF file
MKMonika Kumari
Monika Kumari
R.Radha ..
Radha ..
Manoj KumarManoj Kumar
Manoj Kumar
Baohong ZhangBaohong Zhang
Baohong Zhang
Ryszard AmarowiczRyszard Amarowicz
Ryszard Amarowicz
Jose Manuel LorenzoJose Manuel Lorenzo
Jose Manuel Lorenzo
With the advent of pandemics and infectious diseases, numerous research activities on natural products have been carried out to combat them. Researchers are investigating natural products for the treatment and/or management of various infectious diseases and/or disorders. Acacia catechu (L.f.) Willd. belongs to the family Fabaceae (subfamily Mimosoideae) known as Khair or Cutch tree, possesses diverse pharmacological actions, and has been widely used in Asia and different parts of the world. The purpose of the present study is to highlight the phytochemical profile of different parts of A. catechu, the different biological activities of A. catechu extract, and the utilization of A. catechu as food and beverage. The present work constitutes a review of A. catechu; we performed searches (books, Google, Google Scholar, and Scopus publications) to compile the work/investigations made on A. catechu to the present. From our survey, it was concluded that the main phytochemicals compounds in A. catechu are protocatechuic acid, taxifolin, epicatechin, epigallocatechin, catechin, epicatechin gallate, procyanidin, phloroglucin, aldobiuronic acid, gallic acid, D-galactose, afzelchin gum, L-arabinose, D-rhamnose, and quercetin. The whole plant of A. catechu possesses a comprehensive variety of medicinal potentials such as antimicrobial, antidiarrheal, antinociceptive, antihyperlipidemic, antiulcer, antioxidant, antidiabetic, antiproliferative, haemolytic, and anti-inflammatory properties due to the presence of bioactive compounds like flavonoids, alkaloids, and tannins. However, even though the plant’s metabolites were reported to have many different pharmacological uses, there is limited information about their toxicity or clinical trials. Further research on diverse metabolites of A. catechu should be carried out to ensure the safety or utilization of this plant in the pharma or food industries and in the development of potent plant-based drugs.

26 August 2021 in Antioxidants
Verified
Journal Article
Open access
PDF file
Suraj PrakashSuraj Prakash
Suraj Prakash
R.Radha ..
Radha ..
Manoj KumarManoj Kumar
Manoj Kumar
NKNeeraj Kumari
Neeraj Kumari
MTMamta Thakur
Mamta Thakur
Mohamed MekhemarMohamed Mekhemar
Mohamed Mekhemar
Oral cancer continues to be a leading cause of death worldwide, and its prevalence is particularly high in developing countries, where people chew tobacco and betel nut on a regular basis. Radiation-, chemo-, targeted-, immuno-, and hormone-based therapies along with surgery are commonly used as part of a treatment plan. However, these treatments frequently result in various unwanted short- to long-term side effects. As a result, there is an urgent need to develop treatment options for oral cancer that have little or no adverse effects. Numerous bioactive compounds derived from various plants have recently attracted attention as therapeutic options for cancer treatment. Antioxidants found in medicinal plants, such as vitamins E, C, and A, reduce damage to the mucosa by neutralizing free radicals found in various oral mucosal lesions. Phytochemicals found in medicinal plants have the potential to modulate cellular signalling pathways that alter the cellular defence mechanisms to protect normal cells from reactive oxygen species (ROS) and induce apoptosis in cancer cells. This review aims to provide a comprehensive overview of various medicinal plants and phytoconstituents that have shown the potential to be used as oral cancer therapeutics.

1 October 2021 in Horticulturae
Verified
Journal Article
Open access
PDF file
PPPramod Prakash
Pramod Prakash
R.Radha ..
Radha ..
Manoj KumarManoj Kumar
Manoj Kumar
APAshok Pundir
Ashok Pundir
SPSunil Puri
Sunil Puri
Mohamed Abdel-DaimMohamed Abdel-Daim
Mohamed Abdel-Daim
The aim of current study is to provide a significant traditional knowledge on wild medicines used for ethnoveterinary purposes in the rural area of Maraog region in district Shimla. The medicinal plants have played a significant role in the treatment of human as well as animal’s diseases. The rural people of the Maraog region were interviewed through a questionnaire and extensive field surveys were conducted from June 2020 to July 2021. The discussion, observations and interviews were conducted in study site and included 96 informants. The information gathered from the residents is presented in a table format and includes scientific and local names, different parts used, diseases treated and mode administration. The most commonly used taxa are calculated with used value. The study revealed 100 plants in which trees (7), shrubs (26), herbs (56), ferns (5), grasses (3) and climbers (3) were identified. The most commonly documented livestock diseases were found to be hoof infections, eyes infections, poisoning and skin infections. In the current study, the Rosaceae family was reported as being the highest number (11), followed by Asteraceae (10) and then Lamiaceae (6). It was found that leaves, roots, flowers and fruits are the commonly used parts for ethnoveterinary medications. The phytochemicals present in the plant, such as alkaloids, sterols, glycosides, flavonoids, lignin, coumarins and terpenoids, etc., may be responsible for their medicinal properties. In this documentation, it was observed that the younger generation does not have good knowledge of medicinal plants as compared to the older ones. Therefore, it is necessary to preserve the traditional knowledge of these medicinal plants before their permanent loss. The documentation and conservation of medicinal plants can be a good start for novel phytopharmacological research in the veterinary field.

23 July 2024 in Heliyon
Verified
Journal Article
Open access
APAshok Pundir
Ashok Pundir
MTMohindra SINGH Thakur
Mohindra SINGH Thakur
Suraj PrakashSuraj Prakash
Suraj Prakash
NKNeeraj Kumari
Neeraj Kumari
NSNiharika Sharma
Niharika Sharma
Manoj KumarManoj Kumar
Manoj Kumar
This comprehensive review explores furfural production from agricultural residues, focusing on its significance as a low-volume, high-value asset crucial for environmental sustainability. It covers diverse production technologies, recent advancements, and applications in agriculture, evaluating furfural's potential to enhance crop resilience and yield. Showing its role in a circular economy, the review discusses how furfural can replace conventional petrochemical processes, thereby reducing environmental impact. Case studies, such as successful implementations with cotton biomass byproducts, illustrate furfural's practical applications and environmental benefits. The study underscores the need for ongoing research, supportive policies, and furfural's growing role in sustainable agriculture and industry. It is focused on furfural's essential contribution to promoting environmental stewardship and sustainable practices. By examining furfural's role as a value-added product from agricultural residues, this review provides insights into its economic viability and potential challenges.