This page has only limited features, please log in for full access.

Unclaimed
Sanaullah Iqbal
Department of Food Science and Human Nutrition, University of Veterinary and Animal Sciences, Lahore, Pakistan

Honors and Awards

The user has no records in this section


Career Timeline

The user has no records in this section.


Short Biography

The user biography is not available.
Following
Followers
Co Authors
The list of users this user is following is empty.
Following: 0 users

Feed

Review
Published: 08 February 2021 in Trends in Food Science & Technology
Reads 0
Downloads 0

Iron deficiency anemia [IDA] has emerged as public health concern with poor bioavailability, reliance on dietary cereals and presence of anti-nutritional factors further exacerbating the issue. Strategies like dietary diversification, supplementation, food fortification and bio-fortification have been suggested yet the problem keep on staggering large populations globally. Recent evidence has shown that prebiotics reasoned to fermentation by gut microbiota may lower the pH of the luminal content, boost reduction of Fe (III) to Fe (II), and stimulate expression of mineral-transport proteins in epithelial cells that may enhance the absorption of iron among anemic subjects. However, a detailed study and research needs to be executed to establish this connection. The present review is an attempt to relate the cumulative effect of prebiotics on bioavailability of iron fortificants to effectively address the problem of iron deficiency anemia.

ACS Style

Abdul Momin Rizwan Ahmad; Waqas Ahmed; Sanaullah Iqbal; Mavra Javed; Summer Rashid; Iahtisham- Ul- Haq. Prebiotics and iron bioavailability? Unveiling the hidden association - A review. Trends in Food Science & Technology 2021, 110, 584 -590.

AMA Style

Abdul Momin Rizwan Ahmad, Waqas Ahmed, Sanaullah Iqbal, Mavra Javed, Summer Rashid, Iahtisham- Ul- Haq. Prebiotics and iron bioavailability? Unveiling the hidden association - A review. Trends in Food Science & Technology. 2021; 110 ():584-590.

Chicago/Turabian Style

Abdul Momin Rizwan Ahmad; Waqas Ahmed; Sanaullah Iqbal; Mavra Javed; Summer Rashid; Iahtisham- Ul- Haq. 2021. "Prebiotics and iron bioavailability? Unveiling the hidden association - A review." Trends in Food Science & Technology 110, no. : 584-590.

Original article
Published: 27 October 2020 in Journal of Food Processing and Preservation
Reads 0
Downloads 0

The objective was to evaluate the preservative potential of rutin in combination with butylated hydroxytoluene (BHT) in cheese. Cheddar cheese was prepared with various combinations of rutin (10‐60 ppm) and BHT (60‐240 ppm) along with positive (200 ppm BHT) and a negative control. Tests for antioxidant, storage stability, microbiological and sensory evaluation were performed at 0, 30, 60 and 90 days. Two‐way analysis of variance was applied at p<0.05 followed by a post‐hoc test. Rutin in combination with BHT has significant effect on total phenolic contents and antioxidant activity in linoleic acid at all concentrations. Dose‐dependent significant impact on lipolysis, microbiological stability and sensory attributes, flavor, taste and overall acceptability was observed when compared with control, however, it has no effect on color. It can be concluded that low doses of rutin (40 ppm) with BHT (180 ppm) can increase cheddar cheese stability without adverse effect on sensory attributes.

ACS Style

Bakhtawar Naseer; Sanaullah Iqbal; Namrah Wahid; Haroon Jamshaid Qazi; Muhammad Nadeem; Muhammad Nawaz. Evaluation of antioxidant and antimicrobial potential of rutin in combination with butylated hydroxytoluene in cheddar cheese. Journal of Food Processing and Preservation 2020, 45, 1 .

AMA Style

Bakhtawar Naseer, Sanaullah Iqbal, Namrah Wahid, Haroon Jamshaid Qazi, Muhammad Nadeem, Muhammad Nawaz. Evaluation of antioxidant and antimicrobial potential of rutin in combination with butylated hydroxytoluene in cheddar cheese. Journal of Food Processing and Preservation. 2020; 45 (1):1.

Chicago/Turabian Style

Bakhtawar Naseer; Sanaullah Iqbal; Namrah Wahid; Haroon Jamshaid Qazi; Muhammad Nadeem; Muhammad Nawaz. 2020. "Evaluation of antioxidant and antimicrobial potential of rutin in combination with butylated hydroxytoluene in cheddar cheese." Journal of Food Processing and Preservation 45, no. 1: 1.

Journal article
Published: 01 October 2020 in Journal of Microbiology, Biotechnology and Food Sciences
Reads 0
Downloads 0
ACS Style

Javed Farah; Farah Javed; Zeshan Ali; Sanaullah Iqbal; Naveed Ahmed; Zubair Farooq; Faiza Masood; Muhammad Nawaz. PRODUCTION OF SYNBIOTIC PRODUCT CONTAINING GALACTO-OLIGOSACCHARIDES AND SACCHAROMYCES BOULARDII AND EVALUATION OF ITS IN-VITRO BIFIDOGENIC EFFECT. Journal of Microbiology, Biotechnology and Food Sciences 2020, 10, 197 -200.

AMA Style

Javed Farah, Farah Javed, Zeshan Ali, Sanaullah Iqbal, Naveed Ahmed, Zubair Farooq, Faiza Masood, Muhammad Nawaz. PRODUCTION OF SYNBIOTIC PRODUCT CONTAINING GALACTO-OLIGOSACCHARIDES AND SACCHAROMYCES BOULARDII AND EVALUATION OF ITS IN-VITRO BIFIDOGENIC EFFECT. Journal of Microbiology, Biotechnology and Food Sciences. 2020; 10 (2):197-200.

Chicago/Turabian Style

Javed Farah; Farah Javed; Zeshan Ali; Sanaullah Iqbal; Naveed Ahmed; Zubair Farooq; Faiza Masood; Muhammad Nawaz. 2020. "PRODUCTION OF SYNBIOTIC PRODUCT CONTAINING GALACTO-OLIGOSACCHARIDES AND SACCHAROMYCES BOULARDII AND EVALUATION OF ITS IN-VITRO BIFIDOGENIC EFFECT." Journal of Microbiology, Biotechnology and Food Sciences 10, no. 2: 197-200.

Original research
Published: 14 April 2020 in Food Science & Nutrition
Reads 0
Downloads 0

The present study was designed to assess the incidence of aflatoxin contamination in animal feed and raw milk samples (total 240 each) collected from dairy farms during the complete year of 2015. These samples were collected through a cluster random sampling technique by dividing the province of Punjab, Pakistan into five clusters (north, south, east, west and central). Factors (environmental & physical) affecting aflatoxin contamination in milk and animal feed at farms were also studied. The AFM1 levels in raw milk & AFB1 levels in feed samples were analyzed by using the ELISA technique. Results demonstrated that overall about 53% raw milk samples from dairy farms were contaminated beyond the US MRL (0.50 µg/L) for AFM1 with than average level of 0.59 µg/L, while the 95% farm feed samples were exceeding the FDA MRL (20 µg/kg) of AFB1 with average level of 43 µg/kg. During winter season, the concentration of AFM1 was higher in all clusters with avg 0.68 µg/L, while the AFB1 contamination was highest in the spring season with avg 54 µg/kg. Market feed prices had negative correlation with AFB1 contamilevels, which were further supported by the positive correlation between quantity of feed at farms with AFM1 and AFB1 contamination. Results exhibited significantly positive impact of environmental factors on milk and feed aflatoxin contamination levels, whereas temperature showed an inverse relationship with AFM1 and AFB1 levels. The study recommends need of synergistic extension work to support dairy farms and highlight the contamination levels for regulatory bodies to introduce strategic policies for control measures.

ACS Style

Naveed Akbar; Muhammad Nasir; Naureen Naeem; Mansur‐Ud‐Din Ahmad; Farhan Saeed; Faqir Muhammad Anjum; Sanaullah Iqbal; Muhammad Imran; Tabussam Tufail; Faiz‐Ul‐Hassan Shah; Muhammad Atif. Assessment of aflatoxin in milk and feed samples and impact of seasonal variations in the Punjab, Pakistan. Food Science & Nutrition 2020, 8, 2699 -2709.

AMA Style

Naveed Akbar, Muhammad Nasir, Naureen Naeem, Mansur‐Ud‐Din Ahmad, Farhan Saeed, Faqir Muhammad Anjum, Sanaullah Iqbal, Muhammad Imran, Tabussam Tufail, Faiz‐Ul‐Hassan Shah, Muhammad Atif. Assessment of aflatoxin in milk and feed samples and impact of seasonal variations in the Punjab, Pakistan. Food Science & Nutrition. 2020; 8 (6):2699-2709.

Chicago/Turabian Style

Naveed Akbar; Muhammad Nasir; Naureen Naeem; Mansur‐Ud‐Din Ahmad; Farhan Saeed; Faqir Muhammad Anjum; Sanaullah Iqbal; Muhammad Imran; Tabussam Tufail; Faiz‐Ul‐Hassan Shah; Muhammad Atif. 2020. "Assessment of aflatoxin in milk and feed samples and impact of seasonal variations in the Punjab, Pakistan." Food Science & Nutrition 8, no. 6: 2699-2709.

Journal article
Published: 02 October 2019 in Toxins
Reads 0
Downloads 0

The manifestation of aflatoxins in feed and food is a major issue in the world as its presence leads to some health problems. This study investigates the incidence of aflatoxin M1 (AFM1) contamination in raw milk samples which were collected from Punjab, Pakistan. The Cluster Random Sampling technique was used to collect 960 milk samples from five different regions, and samples were collected every month. The AFM1 level in raw milk was analyzed by the ELISA technique. The findings demonstrate that 70% of samples exceeded the United States permissible maximum residue limits (MRL 0.50 µg/L), with an overall AFM1 level that ranged from 0.3 to 1.0 µg/L. AFM1 contamination varied with the season: The highest average contamination was detected in winter (0.875 µg/L), followed by autumn (0.751 µg/L), spring (0.654 µg/L), and summer (0.455 µg/L). The Eastern region exhibited the highest average AFM1 contamination (0.705 µg/L). Milk samples from the Northern region were found to be widely contaminated, as 86.9% samples exceeded the US MRL, followed by the Eastern region, with 72.3% samples being contaminated with >0.5 µg/L AFM1. The study indicated that the raw milk supply chain was heavily contaminated. Recommendations and remedial measures need to be developed by regulatory authorities to improve the raw milk quality.

ACS Style

Naveed Akbar; Muhammad Nasir; Naureen Naeem; Mansur-Ud-Din Ahmad; Sanaullah Iqbal; Anjum Rashid; Muhammad Imran; Tanweer Aslam Gondal; Muhammad Atif; Bahare Salehi; Javad Sharifi-Rad; Miquel Martorell; William C. Cho. Occurrence and Seasonal Variations of Aflatoxin M1 in Milk from Punjab, Pakistan. Toxins 2019, 11, 574 .

AMA Style

Naveed Akbar, Muhammad Nasir, Naureen Naeem, Mansur-Ud-Din Ahmad, Sanaullah Iqbal, Anjum Rashid, Muhammad Imran, Tanweer Aslam Gondal, Muhammad Atif, Bahare Salehi, Javad Sharifi-Rad, Miquel Martorell, William C. Cho. Occurrence and Seasonal Variations of Aflatoxin M1 in Milk from Punjab, Pakistan. Toxins. 2019; 11 (10):574.

Chicago/Turabian Style

Naveed Akbar; Muhammad Nasir; Naureen Naeem; Mansur-Ud-Din Ahmad; Sanaullah Iqbal; Anjum Rashid; Muhammad Imran; Tanweer Aslam Gondal; Muhammad Atif; Bahare Salehi; Javad Sharifi-Rad; Miquel Martorell; William C. Cho. 2019. "Occurrence and Seasonal Variations of Aflatoxin M1 in Milk from Punjab, Pakistan." Toxins 11, no. 10: 574.

Articles
Published: 21 November 2018 in Women & Health
Reads 0
Downloads 0

Maternal anemia is a frequent problem during pregnancy, especially in developing countries, such as Pakistan. In this context, the present study was conducted to determine factors associated with maternal anemia prevalent among women of different age groups visiting different hospitals in Lahore from February to April 2017. The current study used a cross-sectional design involving 390 pregnant women. Data related to demographic area, maternal age, gestational age/period, educational and income level, as well as socioeconomic status of all the participants were collected. Also, hemoglobin levels of the participants were obtained for assessment of maternal anemia. A total of 57.7% of participants were anemic (34.4 % mild and 23.3% moderate anemia). Bivariate analysis showed that less education (p = 0.01), occupation as housewife (p = 0.03), lower income (p = 0.001), rural residence (p = 0.028), and greater number of house members (p = 0.04) were significantly associated with maternal anemia. Results of multivariable logistic regression showed that low income was the only significant factor independently associated with maternal anemia. These results suggest that interventions, such as the Nutrition Support Program, to improve nutritional status of pregnant women by providing free food supplements with focus on the poor and marginalized communities are recommended to prevent anemia.

ACS Style

Azmat Ullah; Muhammad Sohaib; Farhan Saeed; Sanaullah Iqbal. Prevalence of anemia and associated risk factors among pregnant women in Lahore, Pakistan. Women & Health 2018, 59, 660 -671.

AMA Style

Azmat Ullah, Muhammad Sohaib, Farhan Saeed, Sanaullah Iqbal. Prevalence of anemia and associated risk factors among pregnant women in Lahore, Pakistan. Women & Health. 2018; 59 (6):660-671.

Chicago/Turabian Style

Azmat Ullah; Muhammad Sohaib; Farhan Saeed; Sanaullah Iqbal. 2018. "Prevalence of anemia and associated risk factors among pregnant women in Lahore, Pakistan." Women & Health 59, no. 6: 660-671.

Original research
Published: 27 September 2018 in Journal of the American College of Nutrition
Reads 0
Downloads 0

Objectives: The study was designed to investigate the impact of white sesame seed oil (WSSO) consumption on fasting blood glucose (GLU), insulin (INS), glycosylated hemoglobin (HbA1c), and hepatic antioxidant enzymes. A secondary aim was to check the influence on serum biochemistry, hepatic, cardiac, and renal functions. Methods: Forty-six participants with type 2 diabetes were recruited and randomly divided into two equal groups: diabetic control (DCON) and diabetic sesame oil (DSO). At baseline and 30, 60, and 90 days, blood samples were drawn and analyzed. Two-way repeated-measures analysis of variance was used to evaluate the difference between groups and across time. Results: In both groups, GLU, INS, and HbA1c were not significantly different at baseline (mean 187.07 ± 5.63 mg/dl, mean 12.12 ± 1.03 μU/ml, and mean 7.55 ± 0.37%, respectively). At 90 days, GLU was significantly (p < 0.05) decreased in DSO (137.83 ± 3.16 mg/dl) when compared with DCON (218.13 ± 5.92 mg/dl), while INS was significantly increased in DSO (23.13 ± 1.15 μU/ml) as compared to DCON (7.93 ± 0.38 μU/ml). At 90 days, HbA1c was significantly lower (p < 0.05) in DSO as compared to DCON. Thiobarbituric acid reactive substances were significantly lower (p < 0.05) in DSO (1.08 ± 0.05 [MDA] nmol/ml) as compared to DCON (2.26 ± 0.07 [MDA] nmol/ml). In DSO, activities of hepatic antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase) increased while in DCON these activities decreased significantly (p < 0.05) across the time period. Biomarkers of liver, cardiac, and renal functions improved significantly in DSO as compared to DCON. Conclusion: WSSO as a functional food may play an important role in GLU regulation and against deleterious effects of diabetes in humans with type 2 diabetes.

ACS Style

Farhan Aslam; Sanaullah Iqbal; Muhammad Nasir; Aftab Ahmad Anjum. White Sesame Seed Oil Mitigates Blood Glucose Level, Reduces Oxidative Stress, and Improves Biomarkers of Hepatic and Renal Function in Participants with Type 2 Diabetes Mellitus. Journal of the American College of Nutrition 2018, 38, 235 -246.

AMA Style

Farhan Aslam, Sanaullah Iqbal, Muhammad Nasir, Aftab Ahmad Anjum. White Sesame Seed Oil Mitigates Blood Glucose Level, Reduces Oxidative Stress, and Improves Biomarkers of Hepatic and Renal Function in Participants with Type 2 Diabetes Mellitus. Journal of the American College of Nutrition. 2018; 38 (3):235-246.

Chicago/Turabian Style

Farhan Aslam; Sanaullah Iqbal; Muhammad Nasir; Aftab Ahmad Anjum. 2018. "White Sesame Seed Oil Mitigates Blood Glucose Level, Reduces Oxidative Stress, and Improves Biomarkers of Hepatic and Renal Function in Participants with Type 2 Diabetes Mellitus." Journal of the American College of Nutrition 38, no. 3: 235-246.

Research article
Published: 12 March 2018 in Journal of Chemistry
Reads 0
Downloads 0

β-Glucan is biologically active polysaccharide, ubiquitously found in many grains, bacteria, and fungi and much yeast. The aim of this study was to determine the effect of substituting wheat flour by 1, 2, and 4% yeast isolated β-glucan in cookies on the sensory acceptance, antioxidants, oxidative stability, and quality evaluation which were investigated. According to the results, cookies supplemented at 2% yeast β-glucan were proved satisfactory on sensory quality perspective. During the storage study it was found that cookies made with 2 and 4% β-glucan have effectively (p>0.05) kept the peroxide value (PV) within acceptable range, demonstrating the promising role of β-glucan in deterring oxidative. It is further noted that 2 or 4% β-glucan incorporated cookies assimilated highest absorption spectra, suggesting the retardation in freshness losses, with having minimum microbial loads, showing microbiological safety. β-Glucan fortification in foods is technologically and economically feasible, suggesting that a significant prospect of β-glucan as low-cost food ingredient in formulating cookies at 2% offers exciting new use of β-glucan of yeast origin.

ACS Style

Umar Bacha; Muhammad Nasir; Sanaullah Iqbal; Aftab Ahmad Anjum. Influence of Yeast β-Glucan on Cookies Sensory Characteristics and Bioactivities. Journal of Chemistry 2018, 2018, 1 -8.

AMA Style

Umar Bacha, Muhammad Nasir, Sanaullah Iqbal, Aftab Ahmad Anjum. Influence of Yeast β-Glucan on Cookies Sensory Characteristics and Bioactivities. Journal of Chemistry. 2018; 2018 ():1-8.

Chicago/Turabian Style

Umar Bacha; Muhammad Nasir; Sanaullah Iqbal; Aftab Ahmad Anjum. 2018. "Influence of Yeast β-Glucan on Cookies Sensory Characteristics and Bioactivities." Journal of Chemistry 2018, no. : 1-8.

Journal article
Published: 29 January 2018 in Journal of Food Processing and Preservation
Reads 0
Downloads 0

Prebiotic yogurt (PY) with improved galacto-oligosaccharides (GalOS) was produced through transgalactosylation of lactose followed by physico-chemical and organoleptic evaluation. The chemical composition of fresh and prebiotic milk was statistically (p > .05) similar except for lactose which was reduced from 4.8% in control milk to 1.9% in prebiotic milk. Lactose in PY (1.44 ± 0.01%) was statistically reduced as compared to control yogurt (3.4 ± 0.02%), while other parameters, that is, fat, protein, pH, and acidity were statistically similar. Lactose (60%) was bio-converted producing 0.9 g GalOS, 0.9 g glucose and 0.55 g galactose per 100 g of PY as determined by assay kits and HPLC. The organoleptic evaluation for color, consistency, and overall acceptability was statistically similar for both yogurts while taste and syneresis were improved in PY due to newly produced monosaccharides and GalOS, respectively. It can be concluded that transgalactosylation of milk lactose improves acceptability of PY and is important for lactose intolerant individuals. Lactose intolerance is a serious issue around the globe and it is highly required to produce low lactose or lactose free dairy products. In the present study, major part of milk lactose has been converted to prebiotic galacto-oligosaccharides using beta-galactosidase and the prebiotic milk has been used to produce yogurt with significantly reduced lactose. This process is very much required in dairy industry to produce novel dairy products with reduced lactose.

ACS Style

Awais Raza; Sanaullah Iqbal; Azmat Ullah; Muhammad Imran Khan; Muhammad Imran. Enzymatic conversion of milk lactose to prebiotic galacto-oligosaccharides to produce low lactose yogurt. Journal of Food Processing and Preservation 2018, 42, e13586 .

AMA Style

Awais Raza, Sanaullah Iqbal, Azmat Ullah, Muhammad Imran Khan, Muhammad Imran. Enzymatic conversion of milk lactose to prebiotic galacto-oligosaccharides to produce low lactose yogurt. Journal of Food Processing and Preservation. 2018; 42 (4):e13586.

Chicago/Turabian Style

Awais Raza; Sanaullah Iqbal; Azmat Ullah; Muhammad Imran Khan; Muhammad Imran. 2018. "Enzymatic conversion of milk lactose to prebiotic galacto-oligosaccharides to produce low lactose yogurt." Journal of Food Processing and Preservation 42, no. 4: e13586.

Journal article
Published: 31 August 2017 in International Journal of Molecular Sciences
Reads 0
Downloads 0

Colorectal cancer (CRC) is one of the leading causes of cancer deaths around the globe. Bioactive food ingredients such as prebiotics have protective potential in colon cancer. Data on galacto-oligosaccharides (GalOS) against CRC are very limited and GalOS used in this study have β-1,6 and β-1,3 as major glycosidic linkages and, to our best knowledge, were never used before against any cancer treatment. This study aims to investigate the protective role of novel GalOS against various biomarkers of CRC including aberrant crypt foci (ACF), bacterial enzymes and short chain fatty acids (SCFA) in a rodent model induced with 1,2-dimethylhydrazine dihydrochloride (DMH). Inulin group was taken as positive control in present study to compare novel GalOS protective effects. GalOS doses of 76–151 mg and inulin doses of 114 mg were given to different groups treated with DMH. Results showed that ACF formation was significantly (p ≤ 0.05) less in high dose GalOS group (27.3%). GalOS also had protective effects against DMH-induced body weight loss and showed higher level of cecal and fecal SCFA (acetate, propionate and butyrate). High doses of GalOS also resulted in significant (p ≤ 0.05) reduction of bacterial enzymatic activities. Increased populations of beneficial bacteria (bifidobacteria and lactobacilli) and decreased concentrations of harmful bacteria were observed in all prebiotics treatment groups. It can be concluded that novel GalOS exhibit robust protective activity against ACF formation in vivo.

ACS Style

Tahir Rasool Qamar; Sanaullah Iqbal; Fatima Syed; Muhammad Nasir; Habib Rehman; Muhammad Aamir Iqbal; Rui Hai Liu. Impact of Novel Prebiotic Galacto-Oligosaccharides on Various Biomarkers of Colorectal Cancer in Wister Rats. International Journal of Molecular Sciences 2017, 18, 1785 .

AMA Style

Tahir Rasool Qamar, Sanaullah Iqbal, Fatima Syed, Muhammad Nasir, Habib Rehman, Muhammad Aamir Iqbal, Rui Hai Liu. Impact of Novel Prebiotic Galacto-Oligosaccharides on Various Biomarkers of Colorectal Cancer in Wister Rats. International Journal of Molecular Sciences. 2017; 18 (9):1785.

Chicago/Turabian Style

Tahir Rasool Qamar; Sanaullah Iqbal; Fatima Syed; Muhammad Nasir; Habib Rehman; Muhammad Aamir Iqbal; Rui Hai Liu. 2017. "Impact of Novel Prebiotic Galacto-Oligosaccharides on Various Biomarkers of Colorectal Cancer in Wister Rats." International Journal of Molecular Sciences 18, no. 9: 1785.

Journal article
Published: 01 May 2017 in Journal of Medicinal Food
Reads 0
Downloads 0

White sesame seed oil (WSSO) has been used in cooking and food preparations for centuries. It has many purported health benefits and may be a promising nutraceutical. The primary purpose of this study was to examine the effects of WSSO on fasting blood glucose (GLU) and insulin (INS) in male Sprague-Dawley rats with chemically induced diabetes. A secondary aim was to explore other hematological biomarkers of hepatic, cardiac, and renal function. Sixty-three male Sprague-Dawley rats were randomized into standard diet groups, normal control (NCON) (n = 21) and diabetic control (DCON) (n = 21), and a diabetic sesame oil (DSO) (n = 21) group, which were fed a diet containing 12% WSSO. Blood samples were analyzed at 0, 30, and 60 days. Differences between groups and across days were assessed with two-way repeated measures analysis of variance. At baseline, GLU and INS were similar in both diabetic groups, mean 248.4 ± 2.8 mg/dL and mean 23.4 ± 0.4 μU/mL, respectively. At 60 days, GLU was significantly (P < .05) higher in DCON (298.0 ± 2.3 mg/dL) compared with DSO (202.1 ± 1.0 mg/dL). INS showed similar favorable trends after WSSO supplementation. Consumption of WSSO significantly improved glucose control and other biomarkers of hepatic stress, as well as cardiac and renal health. WSSO may be a viable functional food to help reduce the detrimental effects of diabetes.

ACS Style

Farhan Aslam; Sanaullah Iqbal; Muhammad Nasir; Aftab Ahmad Anjum; Pamela Swan; Karen Sweazea. Evaluation of White Sesame Seed Oil on Glucose Control and Biomarkers of Hepatic, Cardiac, and Renal Functions in Male Sprague-Dawley Rats with Chemically Induced Diabetes. Journal of Medicinal Food 2017, 20, 448 -457.

AMA Style

Farhan Aslam, Sanaullah Iqbal, Muhammad Nasir, Aftab Ahmad Anjum, Pamela Swan, Karen Sweazea. Evaluation of White Sesame Seed Oil on Glucose Control and Biomarkers of Hepatic, Cardiac, and Renal Functions in Male Sprague-Dawley Rats with Chemically Induced Diabetes. Journal of Medicinal Food. 2017; 20 (5):448-457.

Chicago/Turabian Style

Farhan Aslam; Sanaullah Iqbal; Muhammad Nasir; Aftab Ahmad Anjum; Pamela Swan; Karen Sweazea. 2017. "Evaluation of White Sesame Seed Oil on Glucose Control and Biomarkers of Hepatic, Cardiac, and Renal Functions in Male Sprague-Dawley Rats with Chemically Induced Diabetes." Journal of Medicinal Food 20, no. 5: 448-457.

Comparative study
Published: 01 August 2016 in Nutrients
Reads 0
Downloads 0

The selectivity and beneficial effects of prebiotics are mainly dependent on composition and glycosidic linkage among monosaccharide units. This is the first study to use prebiotic galacto-oligosaccharides (GOS) that contains β-1,6 and β-1,3 glycosidic linkages and the novel combination of GOS and inulin in cancer prevention. The objective of the present study is to explore the role of novel GOS and inulin against various biomarkers of colorectal cancer (CRC) and the incidence of aberrant crypt foci (ACF) in a 1,2-dimethyl hydrazine dihydrochloride (DMH)-induced rodent model. Prebiotic treatments of combined GOS and inulin (57 mg each), as well as individual doses (GOS: 76–151 mg; inulin 114 mg), were given to DMH-treated animals for 16 weeks. Our data reveal the significant preventive effect of the GOS and inulin combination against the development of CRC. It was observed that inhibition of ACF formation (55.8%) was significantly (p ≤ 0.05) higher using the GOS and inulin combination than GOS (41.4%) and inulin (51.2%) treatments alone. This combination also rendered better results on short-chain fatty acids (SCFA) and bacterial enzymatic activities. Dose-dependent effects of prebiotic treatments were also observed on cecum and fecal bacterial enzymes and on SCFA. Thus, this study demonstrated that novel combination of GOS and inulin exhibited stronger preventive activity than their individual treatments alone, and can be a promising strategy for CRC chemoprevention.

ACS Style

Tahir Rasool Qamar; Fatima Syed; Muhammad Nasir; Habib Rehman; Muhammad Nauman Zahid; Rui Hai Liu; Sanaullah Iqbal. Novel Combination of Prebiotics Galacto-Oligosaccharides and Inulin-Inhibited Aberrant Crypt Foci Formation and Biomarkers of Colon Cancer in Wistar Rats. Nutrients 2016, 8, 465 .

AMA Style

Tahir Rasool Qamar, Fatima Syed, Muhammad Nasir, Habib Rehman, Muhammad Nauman Zahid, Rui Hai Liu, Sanaullah Iqbal. Novel Combination of Prebiotics Galacto-Oligosaccharides and Inulin-Inhibited Aberrant Crypt Foci Formation and Biomarkers of Colon Cancer in Wistar Rats. Nutrients. 2016; 8 (8):465.

Chicago/Turabian Style

Tahir Rasool Qamar; Fatima Syed; Muhammad Nasir; Habib Rehman; Muhammad Nauman Zahid; Rui Hai Liu; Sanaullah Iqbal. 2016. "Novel Combination of Prebiotics Galacto-Oligosaccharides and Inulin-Inhibited Aberrant Crypt Foci Formation and Biomarkers of Colon Cancer in Wistar Rats." Nutrients 8, no. 8: 465.