Farhan Saeed

Dr. Farhan Saeed

Department of Food Science & Technology, Government College University Faisalabad, Faisalabad, Pakistan

Research Focus & Metrics

Academic Career Length

16Years (2011-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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19 June 2019 in Molecules
Verified
Journal Article
Open access
PDF file
MIMuhammad Imran
Muhammad Imran
BSBahare Salehi
Bahare Salehi
Javad Sharifi-RadJavad Sharifi-Rad
Javad Sharifi-Rad
TGTanweer Aslam Gondal
Tanweer Aslam Gondal
FSFarhan Saeed
Farhan Saeed
Leticia M. EstevinhoLeticia M. Estevinho
Leticia M. Estevinho
A marked decrease in human cancers, including breast cancer, bone cancer, and cervical cancer, has been linked to the consumption of vegetable and fruit, and the corresponding chemoprotective effect has been associated with the presence of several active molecules, such as kaempferol. Kaempferol is a major flavonoid aglycone found in many natural products, such as beans, bee pollen, broccoli, cabbage, capers, cauliflower, chia seeds, chives, cumin, moringa leaves, endive, fennel, and garlic. Kaempferol displays several pharmacological properties, among them antimicrobial, anti-inflammatory, antioxidant, antitumor, cardioprotective, neuroprotective, and antidiabetic activities, and is being applied in cancer chemotherapy. Specifically, kaempferol-rich food has been linked to a decrease in the risk of developing some types of cancers, including skin, liver, and colon. The mechanisms of action include apoptosis, cell cycle arrest at the G2/M phase, downregulation of epithelial-mesenchymal transition (EMT)-related markers, and phosphoinositide 3-kinase/protein kinase B signaling pathways. In this sense, this article reviews data from experimental studies that investigated the links between kaempferol and kaempferol-rich food intake and cancer prevention. Even though growing evidence supports the use of kaempferol for cancer prevention, further preclinical and clinical investigations using kaempferol or kaempferol-rich foods are of pivotal importance before any public health recommendation or formulation using kaempferol.

18 December 2016 in International Journal of Food Properties
Verified
Journal Article
Open access
MAMunawar Abbas
Munawar Abbas
FSFarhan Saeed
Farhan Saeed
FAFaqir Muhammad Anjum
Faqir Muhammad Anjum
MAMuhammad Afzaal
Muhammad Afzaal
TTTabussam Tufail
Tabussam Tufail
Hafiz SuleriaHafiz Suleria
Hafiz Suleria
Plant-derived functional foods are gaining considerable attention due to their safety and therapeutic potentials. Research on plant-based functional foods presents several challenges ranges from hypercholesterolemia to cancer prevention. In last decade, special attention has been paid to edible plants and especially their phytochemicals. Today, there is an increasing interest in their bioactivities provided by these phytochemicals. Polyphenols are the most numerous and widely distributed group of bioactive molecules. Polyphenols have two general classes, one is flavonoids and other is phenolic acids. Among these, flavonoids are further divided into flavones, flavononse, flavonols, flavanols, isoflavones, and phenolic acids are generally classified into hydroxybenzoic and hydroxycinnamic acids. Fruit peel is one of the dense sources for flavonoids and their content may vary from species to species and due to exposure of light. Polyphenols have wide range of molecules and different set of biological activities that are mainly attributed to their structure. Investigations have revealed that polyphenols play a key role to prevent various diseases, like hypercholesterolemia, hyperglycemia, hyperlipidemia, and cancer insurgence. The current review article summarizes the literature pertaining to polyphenols and its allied health benefits.

30 March 2023 in Polymers
Verified
Journal Article
Open access
PDF file
YSYasir Abbas Shah
Yasir Abbas Shah
Saurabh BhatiaSaurabh Bhatia
Saurabh Bhatia
Ahmed Al-HarrasiAhmed Al-Harrasi
Ahmed Al-Harrasi
Muhammad AfzaalMuhammad Afzaal
Muhammad Afzaal
FSFarhan Saeed
Farhan Saeed
ZFZargham Faisal
Zargham Faisal
The quality and safety of food products greatly depend on the physiochemical properties of the food packaging material. There is an increasing trend in the utilization of protein-based biopolymers for the preparation of edible films and coating due to their film-forming properties. Various studies have reported the preparation of protein-based edible films with desirable mechanical and barrier properties. The mechanical attributes of the protein-based food packaging materials can be enhanced by incorporating various components in the film composition such as plasticizers, surfactants, crosslinkers, and various bioactive compounds, including antimicrobial and antioxidant compounds. This review article summarizes the recent updates and perspective on the mechanical attributes such as Tensile Strength (TS), Elongation at Break (EAB), and Young’s Modulus (YM) of edible films based on different proteins from plants and animal sources. Moreover, the effects of composite materials such as other biopolymers, bioactive compounds, essential oils, and plasticizers on the mechanical properties of protein-based edible films are also discussed.

15 May 2022 in International Journal of Food Properties
Verified
Journal Article
Open access
IUIfrah Usman
Ifrah Usman
Muzzamal HussainMuzzamal Hussain
Muzzamal Hussain
AIAli Imran
Ali Imran
Muhammad AfzaalMuhammad Afzaal
Muhammad Afzaal
FSFarhan Saeed
Farhan Saeed
SSShamaail A. Saewan
Shamaail A. Saewan
Consumers demand for functional foods and nutraceutical is increasing owing to their health endorsing properties. Natural bioactive compounds are getting attention due to their health promoting potential. In addition, the extraction of these bioactive compounds is a significant industrial and technological perspectives. These bioactive moieties can be extracted via various conventional and modern methods. For instance; solid-phase extraction, solid-phase micro-extraction, and liquid-liquid extraction are considered as traditional/conventional methods. In contrast, modern eco-innovative methods for extraction such as ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE), pulsed electric field (PEF), supercritical fluid extraction (SFE), instant controlled pressure drop (DIC), etc. are more economical and environment friendly. Additionally, these are ever-increasing demands of energy-efficient methods for the recovery of valuable compounds. Moreover, these methods produced less wastewater and hazardous substances. Conclusively, this review highlighted the conventional and modern extraction technologies and the role of these eco-innovative technologies in achieving the goal of a sustainable food system.

11 August 2021 in Food Science & Nutrition
Verified
Journal Article
Open access
PDF file
MIMuhammad Imran
Muhammad Imran
FSFarhan Saeed
Farhan Saeed
GHGhulam HUSSAIN
Ghulam HUSSAIN
AIAli Imran
Ali Imran
ZMZaffar Mehmood
Zaffar Mehmood
SISaiful Islam
Saiful Islam
Myricetin is a critical nutritive component of diet providing immunological protection and beneficial for maintaining good health. It is found in fruits, vegetables, tea, and wine. The families Myricaceae, Polygonaceae, Primulaceae, Pinaceae, and Anacardiaceae are the richest sources of myricetin. Different researchers explored the therapeutic potential of this valuable constituent such as anticancer, antidiabetic, antiobesity, cardiovascular protection, osteoporosis protection, anti‐inflammatory, and hepatoprotective. In addition to these, the compound has been tested for cancer and diabetic mellitus during clinical trials. Health benefits of myricetin are related to its impact on different cell processes, such as apoptosis, glycolysis, cell cycle, energy balance, lipid level, serum protein concentrations, and osteoclastogenesis. This review explored the potential health benefits of myricetin with a specific emphasis on its mechanism of action, considering the most updated and novel findings in the field.

23 June 2021 in Food Science & Nutrition
Verified
Journal Article
Open access
PDF file
AIAli Ikram
Ali Ikram
FSFarhan Saeed
Farhan Saeed
MAMuhammad Afzaal
Muhammad Afzaal
AIAli Imran
Ali Imran
BNBushra Niaz
Bushra Niaz
FAFaqir Muhammad Anjum
Faqir Muhammad Anjum
Scientific literature is evident that the germinated seeds possess a promising potential for essential nutrients, flavors, and textural attributes over nongerminated grain. In recent decades, sprouting has also been investigated as a potential green food engineering technique to boost the nutritive profile of grains. Sprouting grains have multifold applications in different fields such as baking, pharmaceutical, and cosmetic industries. During sprouting, shifting of molecular structures to macroscopic takes place. Sprouting reactivates the grain metabolism which leads to the catabolism and degradation of antinutrient and macronutrient compounds. These modifications have an effect on human health and on the nutritional content of the foodstuffs. Sprouting grains have high bioactivity against diabetes and cancer. Germination is also an outstanding green food development technique to increase the seed nutritive profile in terms of quality. The present review focuses on the sprouting of grains, changes in nutritional profile, and the technological exploration of sprouted grains.