Infectious diseases poses a growing public health challenge. The COVID-19 pandemic has further emphasized the urgent need for rapid, accessible diagnostics. This study presents the development of an integrated, flexible point-of-care (POC) diagnostic system for the rapid detection of Corynebacterium diphtheriae, the pathogen responsible for diphtheria. The system comprises a microfluidic polymerase chain reaction (micro-PCR) device and an electrochemical DNA biosensor, both fabricated on flexible substrates. The micro-PCR platform offers rapid DNA amplification overcoming the time limitations of conventional thermocyclers. The biosensor utilizes specific molecular recognition and an electrochemical transducer to detect the amplified DNA fragment, providing a clear and direct indication of the pathogen’s presence. The combined system demonstrates the effective amplification and detection of a gene fragment from a toxic strain of C. diphtheriae, chosen due to its increasing incidence. The design leverages lab-on-a-chip (LOC) and microfluidic technologies to minimize reagent use, reduce cost, and support portability. Key challenges in microsystem design—such as flow control, material selection, and reagent compatibility—were addressed through optimized fabrication techniques and system integration. This work highlights the feasibility of using flexible, integrated microfluidic and biosensor platforms for the rapid, on-site detection of infectious agents. The modular and scalable nature of the system suggests potential for adaptation to a wide range of pathogens, supporting broader applications in global health diagnostics. The approach provides a promising foundation for next-generation POC diagnostic tools.
In 2018, the European Parliament and Council laid down a directive about the promotion of the use of energy from renewable sources connected with the Paris Agreement, which sets a global ambition on climate change mitigation through deep and fast cuts in greenhouse gas emissions. Since then, the science world has been even more focused on the development of green technologies such as wind farms, waterpower stations, and photovoltaics as the European Union is preparing to shift to renewables-based energy systems. Each green power technology has its own problems and limitations. Nevertheless, for environmental protection, new power technologies have to be implemented in the near future as primary power sources. Described in this article is the application of aerosol jet printing in manufacture of photovoltaic cells, moving the technology boundaries further toward highly efficient, cost-effective, green power production. The research focused on utilizing aerosol jet printing technology to create finger-shaped collecting electrodes on a newly constructed, non-silicon photovoltaic cell, based on metal oxides. Three commercial nanosilver inks were investigated considering their printing parameters, printability on the specified substrate (AZO-coated glass, AZO-coated copper plate), resistivity of the cured composite, quality of the overprints, and application in photovoltaics. As a result, we obtained finger-shaped collecting electrodes with a resistivity of 3.5 µΩ∙cm and 8 µm width, which compares well with the literature.
With the increase in the popularity of wearable and integrated electronics, a proper way to manufacture electronics on textiles is needed. This study aims to analyze the effect of different parameters of the heat transfer process on the electrical and mechanical properties of flexible electronics made on textiles, presenting it as a viable method of producing such electronics. Wires made from different composites based on silver microparticles and an insulating layer were screen-printed on a release film. Then, they were transferred onto a polyester cloth using heat transfer with different parameters. Research showed that different heat transfer parameters could influence the electrical properties of screen-printed wires, changing their resistance between −15% and +150%, making it imperative to adjust those properties depending on the materials used. Changes in the settings of heat transfer also influence mechanical properties, increasing adhesion between layers at higher temperatures. This study shows the importance of tailoring heat transfer properties and the differences that these properties make.
This study explores the potential benefits of combining different printing techniques to improve the production of flexible printed sensors, which is a relevant application for modern coating and surface design. The demand for cheap, flexible, precise, and scalable sensors for wearable electronics is increasing, and printed electronics techniques have shown great potential in meeting these requirements. To achieve higher performance and synergy, the paper introduces the concept of hybrid printing of electronics by combining aerosol jet printing and screen printing. This multi-process approach allows for large-scale production with high printing precision. The study prepares hybrid connections on a flexible substrate foil for use in flexible printed sensor manufacturing. The research team tests different combinations of printed layers and annealing processes and finds that all prepared samples exhibit high durability during mechanical fatigue tests. Surface morphology, SEM images, and cross-section profiles demonstrate the high quality of printed layers. The lowest resistance among the tested hybrid connections obtained was 1.47 Ω. The study’s findings show that the hybrid printing approach offers a novel and promising solution for the future production of flexible sensors. Overall, this research represents an interdisciplinary approach to modern coating and surface design that addresses the need for improved production of wearable electronics. By combining different printing techniques, the study demonstrates the potential for achieving high-volume production, miniaturization, and high precision, which are essential for the ever-growing market of wearable sensors.