Sequential cropping in the Biogasdoneright™ (BDR™) system in Italy has recently gained attention to combine food and renewable energy production in a sustainable way, as well as for carbon sequestration. However, little is known on the potential to expand the practice in other regions of Europe. In this paper, sequential crop calendars were developed for different EU climate regions, and the EU biomethane potential of the anaerobic digestion (AD) of sequential crops was estimated for a Conservative_Scenario and a Maximum_Scenario, assuming different percentages of primary crop land dedicated to the practice and biogas yields. A total EU biomethane potential of 46 bcm/yr and 185 bcm/yr was estimated from the AD of sequential crops in the two scenarios, respectively, and the Continental region registered the highest potential compared to the other regions. The additional benefits of the combination of sequential cropping with other agricultural conservation practices and digestate use included in BDR™ systems were also discussed. In conclusion, the paper shows that with appropriate innovations in crop management, sequential cropping could be applied in different agroclimatic regions of Europe, contributing to climate and renewable energy targets.