John Oluwafemi Teibo

Dr. John Oluwafemi Teibo

Department of Biochemistry and Immunology, University of São Paulo, Ribeirão Prêto, São Paulo, Brazil
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Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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11 September 2023 in International Journal for Equity in Health
Verified
Journal Article
Open access
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OOOlabode Omotoso
Olabode Omotoso
John Oluwafemi TeiboJohn Oluwafemi Teibo
John Oluwafemi Teibo
FAFestus Adebayo Atiba
Festus Adebayo Atiba
TOTolulope Oladimeji
Tolulope Oladimeji
OPOluwatomiwa Kehinde Paimo
Oluwatomiwa Kehinde Paimo
AAAthanasios Alexiou
Athanasios Alexiou
Introduction: Cancer is a significant public health challenge globally, with nearly 2000 lives lost daily in Africa alone. Without adequate measures, mortality rates are likely to increase. The major challenge for cancer care in Africa is equity and prioritization, as cancer is not receiving adequate attention from policy-makers and strategic stakeholders in the healthcare space. This neglect is affecting the three primary tiers of cancer care: prevention, diagnosis, and treatment/management. To promote cancer care equity, addressing issues of equity and prioritization is crucial to ensure that everyone has an equal chance at cancer prevention, early detection, and appropriate care and follow-up treatment. Methodology: Using available literature, we provide an overview of the current state of cancer care in Africa and recommendations to close the gap. Results: We highlight several factors that contribute to cancer care inequity in Africa, including inadequate funding for cancer research, poor cancer education or awareness, inadequate screening or diagnostic facilities, lack of a well-organized and effective cancer registry system and access to care, shortage of specialized medical staff, high costs for screening, vaccination, and treatment, lack of technical capacity, poor vaccination response, and/or late presentation of patients for cancer screening. We also provide recommendations to address some of these obstacles to achieving cancer care equity. Our recommendations are divided into national-level initiatives and capacity-based initiatives, including cancer health promotion and awareness by healthcare professionals during every hospital visit, encouraging screening and vaccine uptake, ensuring operational regional and national cancer registries, improving healthcare budgeting for staff, equipment, and facilities, building expertise through specialty training, funding for cancer research, providing insurance coverage for cancer care, and implementing mobile health technology for telemedicine diagnosis. Conclusion: Addressing challenges to cancer equity holistically would improve the likelihood of longer survival for cancer patients, lower the risk factors for groups that are already at risk, and ensure equitable access to cancer care on the continent. This study identifies the existing stance that African nations have on equity in cancer care, outlines the current constraints, and provides suggestions that could make the biggest difference in attaining equity in cancer care.

11 February 2023 in Naunyn-Schmiedeberg's Archives of Pharmacology
Verified
Journal Article
Open access
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Gaber El-Saber BatihaGaber El-Saber Batiha
Gaber El-Saber Batiha
John Oluwafemi TeiboJohn Oluwafemi Teibo
John Oluwafemi Teibo
LWLamiaa Wasef
Lamiaa Wasef
Hazem ShaheenHazem Shaheen
Hazem Shaheen
Ayomide Peter AkomolafeAyomide Peter Akomolafe
Ayomide Peter Akomolafe
MPMarios Papadakis
Marios Papadakis
Lavandula species is a flowering plant that is common in Europe and across the Mediterranean. Lavender has many health benefits for humans. In addition to its use in herbal medicine, it is widely used in the fields of cosmetics, perfumes, foods, and aromatherapy. Google Scholar, PubMed, Scopus, and Web of Science were used to search for relevant material on the phytochemical ingredients, the pharmacologic effects of the ingredients, and the mechanism of action of the Lavandula species identified. These materials were reviewed in order to have access to important updates about the Lavandula species. Lavender as referred to in English contains essential oils, anthocyanins, phytosterols, sugars, minerals, coumaric acid, glycolic acid, valeric acid, ursolic acid, herniarins, coumarins, and tannins. It has been used to treat colic and chest ailments, worrisome headaches, and biliousness, and in cleaning wounds. It has antifungal, antibacterial, neurologic, antimicrobial, anti-parasitic, anti-diabetic, and analgesic effects among others. Lavandula species has prospects for various biological applications, especially with its dermatological application. Advances in drug development would enable characterization of various bioactive constituents; thus, its development and application can have a more positive impact on humanity. Here, we highlighted updated information on the history, distribution, traditional uses, phytochemical components, pharmacology, and various biological activities of Lavandula species.

18 November 2022 in Naunyn-Schmiedeberg's Archives of Pharmacology
Verified
Journal Article
Open access
PDF file
Gaber El-Saber BatihaGaber El-Saber Batiha
Gaber El-Saber Batiha
LWLamiaa Wasef
Lamiaa Wasef
John Oluwafemi TeiboJohn Oluwafemi Teibo
John Oluwafemi Teibo
Hazem ShaheenHazem Shaheen
Hazem Shaheen
Ali Muhammad ZakariyaAli Muhammad Zakariya
Ali Muhammad Zakariya
MPMarios Papadakis
Marios Papadakis
Medicinal plants have a long track record of use in history, and one of them is Commiphora myrrh which is commonly found in the southern part of Arabia, the northeastern part of Africa, in Somalia, and Kenya. Relevant literatures were accessed via Google Scholar, PubMed, Scopus, and Web of Science to give updated information on the phytochemical constituents and pharmacological action of Commiphora myrrh. It has been used traditionally for treating wounds, mouth ulcers, aches, fractures, stomach disorders, microbial infections, and inflammatory diseases. It is used as an antiseptic, astringent, anthelmintic, carminative, emmenagogue, and as an expectorant. Phytochemical studies have shown that it contains terpenoids (monoterpenoids, sesquiterpenoids, and volatile/essential oil), diterpenoids, triterpenoids, and steroids. Its essential oil has applications in cosmetics, aromatherapy, and perfumery. Research has shown that it exerts various biological activities such as anti-inflammatory, antioxidant, anti-microbial, neuroprotective, anti-diabetic, anti-cancer, analgesic, anti-parasitic, and recently, it was found to work against respiratory infections like COVID-19. With the advancement in drug development, hopefully, its rich phytochemical components can be explored for drug development as an insecticide due to its great anti-parasitic activity. Also, its interactions with drugs can be fully elucidated.This review highlights an updated information on the history, distribution, traditional uses, phytochemical components, pharmacology, and various biological activities of Commiphora myrrh. Graphical abstract Graphical summary of the phytochemical and pharmacological update of Commiphora myrrh

6 March 2023 in Naunyn-Schmiedeberg's Archives of Pharmacology
Verified
Journal Article
Open access
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Gaber El-Saber BatihaGaber El-Saber Batiha
Gaber El-Saber Batiha
AAAli Esmail Al-Snafi
Ali Esmail Al-Snafi
MTMahdi M. Thuwaini
Mahdi M. Thuwaini
John Oluwafemi TeiboJohn Oluwafemi Teibo
John Oluwafemi Teibo
Hazem ShaheenHazem Shaheen
Hazem Shaheen
MPMarios Papadakis
Marios Papadakis
Morusalba is a fast-growing shrub or medium-sized tree with a straight, cylindrical trunk. Medicinally, whole plants, leaves, fruits, branches, and roots have been employed. Google Scholar, PubMed, Scopus, and Web of Science were used to search for relevant material on the phytochemical components and pharmacologic and mechanism of action of the Morus alba. This was reviewed to assess important updates about Morus alba. The fruits of Morus alba have traditionally been used as an analgesic, anthelmintic, antibacterial, anti-rheumatic, diuretic, hypotensive, hypoglycemia, purgative, restorative, sedative tonic, and blood stimulant. Various plant parts were used as a cooling, sedating, diuretic, tonic, and astringent agent to treat nerve disorders. The plant contained tannins, steroids, phytosterols, sitosterol, glycosides, alkaloids, carbohydrates, proteins, and amino acids, as well as saponins, triterpenes, phenolics, flavonoids, benzofuran derivatives, anthocyanins, anthraquinones, glycosides, vitamins, and minerals. Previous pharmacological research identified antimicrobial, anti-inflammatory, immunological, analgesic, antipyretic, antioxidant, anti-cancer, antidiabetic, gastrointestinal, respiratory, cardiovascular, hypolipidemic, anti-obesity, dermatological, neurological, muscular, and protecting effects. This study looked at Morus alba’s traditional uses, chemical components, and pharmacological effects.

15 June 2022 in Public Health Challenges
Verified
Journal Article
Open access
YAYusuff Adebisi
Yusuff Adebisi
INIfechukwu Benedict Nwogu
Ifechukwu Benedict Nwogu
AAAishat Jumoke Alaran
Aishat Jumoke Alaran
ABAbubakar Olaitan Badmos
Abubakar Olaitan Badmos
ABAdeboye Olakunle Bamgboye
Adeboye Olakunle Bamgboye
WAWuraola Akande‐Sholabi
Wuraola Akande‐Sholabi
Background: Access to safe, effective, affordable, and quality medicines is an essential component of the right to health and is also one of the targets in the global development agenda. In this review article, we extensively discuss the challenges and issues surrounding access to medicines in the African region as well as provides recommendations for ensuring medicines security on the continent.Methods: We conducted narrative review with the use of data reported in published literature, reports, and grey literature available in African countries on topics pertaining access to medicines. The authors also snowballed further data to gather information for this review and narrative synthesis was conducted.Results: Africa faces a double burden of infectious and non‐communicable diseases and the need for effective universal access to medicines cannot be deemphasized. However, access to medicines on the continent is not without issues and challenges. Some of which are the high burden of infectious diseases and non‐infectious diseases, limited pharmaceutical industries and high costs of raw materials, overdependence on countries abroad for medicines, poor supply chain systems, lack of government investment in the pharmaceutical sector, unfavourable manufacturing conditions, limited health workforce, lack of sustainable health financing mechanisms, lack of infrastructures and technical know‐how, low investment on research and development, and circulation of fake and counterfeit medicines among others.Conclusion: This review reifies that access to medicines in Africa faces numerous challenges and it emphasizes the urgent need to address these issues as the continent geared towards strengthening its health systems for universal health coverage.

9 December 2022 in Globalization and Health
Verified
Journal Article
Open access
PDF file
OOOlabode Omotoso
Olabode Omotoso
John Oluwafemi TeiboJohn Oluwafemi Teibo
John Oluwafemi Teibo
FAFestus Adebayo Atiba
Festus Adebayo Atiba
TOTolulope Oladimeji
Tolulope Oladimeji
AAAyomide Oluwadarasimi Adebesin
Ayomide Oluwadarasimi Adebesin
ABAhmed O. Babalghith
Ahmed O. Babalghith
This paper highlights the gap in the use of genomic data of Africans for global research efforts for disease cures. Genomic data represents an important tool used in disease research for understanding how diseases affect several populations and how these differences can be harnessed for the development of effective cures especially vaccines that have an impact at the genetic level e.g., RNA vaccines.This paper then provides a review of global genomic data status where three continents are reported to be the major contributor of genomic data to repositories used for disease research and the development of vaccines and medicines around the world.We reviewed the most recently published information about genetic data inclusiveness of populations, explaining how genomic data of Africans is lacking in global research efforts that cater towards the eradication of pandemics via the development of vaccines and other cures. We also discuss the implication of this non-inclusiveness for global disease burdens and indicate where changes need to be made in the last part of the paper.Lastly, the entire centers on some general policy recommendations to fully include African genomic data in such global genetic repositories. These recommendations can be implemented in African countries to improve genetic data collection, storage, and usage policies.