Lanthanide (Ln³⁺)–doped upconversion nanoparticles (UCNPs) offer an ennormous future for a broad range of biological applications over the conventional downconversion fluorescent probes such as organic dyes or quantum dots. Unfortunately, the efficiency of the anti−Stokes upconversion luminescence (UCL) process is typically much weaker than that of the Stokes downconversion emission. Albeit recent development in the synthesis of UCNPs, it is still a major challenge to produce a high−efficiency UCL, meeting the urgent need for practical applications of enhanced markers in biology. The poor quantum yield efficiency of UCL of UCNPs is mainly due to the fol-lowing reasons: (i) the low absorption coefficient of Ln³⁺ dopants, the specific Ln³⁺ used here being ytterbium (Yb³⁺), (ii) UCL quenching by high−energy oscillators due to surface defects, impurities, ligands, and solvent molecules, and (iii) the insufficient local excitation intensity in broad-field il-lumination to generate a highly efficient UCL. In order to tackle the problem of low absorption cross-section of Ln3+ ions, we first incorporate a new type of neodymium (Nd³⁺) sensitizer into UCNPs to promote their absorption cross-section at 793 nm. To minimize the UCL quenching induced by surface defects and surface ligands, the Nd³⁺-sensitized UCNPs are then coated with an inactive shell of NaYF₄. Finally, the excitation light intensity in the vicinity of UCNPs can be greatly enhanced using a waveguide grating structure thanks to the guided mode resonance. Through the synergy of these three approaches, we show that the UCL intensity of UCNPs can be boosted by a million−fold compared with conventional Yb³⁺–doped UCNPs.

We have proposed a fruitful design principle targeting a concentration ratio (CR) >1000× for a typical high concentrating photovoltaics (HCPV) system, on account of a two-concentrator system + homogenizer. The principle of a primary dual-lens concentrator unit, completely analogous basic optics seen in the superposition compound eyes, is a trend not hitherto reported for solar concentrators to our knowledge. Such a concentrator unit, consisting of two aspherical lenses, can be applied to minify the sunlight and reveal useful effects. We underline that, at this stage, the CR can be attained by two orders of magnitude simply by varying the radius ratio of such two lenses known from the optics side. The output beam is spatially minimized and nearly parallel, exactly as occurs in the superposition compound eye. In our scheme, thanks to such an array of dual-lens design, a sequence of equidistant focal points is formed. The secondary concentrator consists of a multi-reflective channel, which can collect all concentrated beams from the primary concentrator to a small area where a solar cell is placed. The secondary concentrator is located right underneath the primary concentrator. The optical characteristics are substantiated by optical simulations that confirm the applicability of thousands-fold gain in CR value, ~1100×. This, however, also reduced the uniformity of the illumination area. To regain the uniformity, we devise a fully new homogenizer, hinging on the scattering principle. A calculated optical efficiency for the entire system is ~75%. Experimentally, a prototype of such a dual-lens concentrator is implemented to evaluate the converging features. As a final note, we mention that the approach may be extended to implement an even higher CR, be it simply by taking an extra concentrator unit. With simple design of the concentrator part, which may allow the fabrication process by modeling method and large acceptant angle (0.6°), we assess its large potential as part of a general strategy to implement a highly efficient CPV system, with minimal critical elaboration steps and large flexibility.

We introduce a compact array fluorescence sensor principle that takes advantage of the long luminescence lifetimes of upconversion nanoparticles (UCNPs) to deploy a filter-free, optics-less contact geometry, advantageous for modern biochemical assays of biomolecules, pollutants or cells. Based on technologically mature CMOS chips for ∼10 kHz technical/scientific imaging, we propose a contact geometry between assayed molecules or cells and a CMOS chip that makes use of only a faceplate or direct contact, employing time-window management to reject the 975 nm excitation light of highly efficient UCNPs. The chip surface is intended to implement, in future devices, a resonant waveguide grating (RWG) to enhance excitation efficiency, aiming at the improvement of upconversion luminescence emission intensity of UCNP deposited atop of such an RWG structure. Based on mock-up experiments that assess the actual chip rejection performance, we bracket the photometric figures of merit of such a promising chip principle and predict a limit of detection around 10-100 nanoparticles.