Osteoarthritis (OA) is a common and debilitating condition in domestic dogs. Alongside pharmaceutical interventions and weight loss, exercise and physiotherapy (PT) are important measures in maintaining patient mobility and quality of life. Physiotherapy for OA aims to reduce pain, optimize muscular function and maintain joint function. Physiotherapeutic plans typically include PT exercises combined with therapeutic modalities, lifestyle and environmental modifications to improve the patient’s overall quality of life and function. Information on therapeutic clinical efficacy of physiotherapeutic measures for canine OA is still very limited. Thus, physiotherapeutic strategies are still primarily based on evidence extrapolated from human protocols tailored to people with OA. The authors propose a simple systematic PT approach for canine OA, prioritizing measures according to simplicity, cost effectiveness and practicality. This guide (the “Physiotherapy Pyramid”) aims to provide a clear stratified approach to simplify decision making and planning for owners, veterinarians and veterinary physiotherapists, leading to more straightforward design and implementation of treatment plans. Measures are implemented starting at the base of the pyramid, subsequently progressing to the top, allowing effective and practical interventions to be prioritized. The levels of the pyramid are in ascending order: environmental modification, exercise plan, OA-specific home exercises and treatment by a veterinary physiotherapist.

Reliable, standardized balance tests for dogs are not available yet. The purpose of this study was to investigate the reliability of static and dynamic posturography in healthy dogs. Healthy dogs (n = 20) were positioned with four paws longitudinally and with the forepaws only transversely on a modified pressure-sensitive balance platform (Posturomed-FDM-JS, Zebris, Isny, Germany). Three static and dynamic posturographic trials were recorded (recording duration: 20 s) and repeated after 7–14 days. Center of pressure (COP) parameters COP-path-length (PL; mm), 95% COP-confidence-ellipse-area (CEA; mm²), and COP-average-velocity (AV; mm/s) were calculated for the first steady-state 5 s intervals of each trial. The reliability of COP parameters was assessed with robust linear mixed effects models with nested random effects of patient and trial. The training effect was analyzed using Cohen’s d. For static posturography, PL, CEA, and AV did not differ significantly between time points; CEA had the highest reliability (p = 0.92). For dynamic posturography, AV and PL differed significantly between time points (AV: p ≤ 0.043; PL: p ≤ 0.045). Slight training effects were observed for transverse positioning (Cohen’s d: PL 0.65; AV 0.267) and moderate training effects for longitudinal positioning (Cohen’s d: PL: 0.772; AV: 0.783). This study showed that static posturography on a modified Posturomed-balance platform was reliable in healthy dogs but indicated training effects during dynamic posturography.

Objective: Betahistine is frequently used in the pharmacotherapy for Menière’s Disease (MD). Little is known about its mode of action and prescribed dosages vary. While betahistine had an increasing effect on cochlear microcirculation in earlier studies, low dose betahistine of 0.01 mg/kg bw or less was not able to effect this. Selegiline inhibits monoaminooxidase B and therefore potentially the breakdown of betahistine. The goal of this study was to examine whether the addition of selegiline to low dose betahistine leads to increased cochlear blood flow. Methods: Twelve Dunkin-Hartley guinea pigs were anesthetized, the cochlea was exposed and a window opened to the stria vascularis. Blood plasma was visualized by injecting fluoresceinisothiocyanate-dextrane and vessel diameter and erythrocyte velocity were evaluated over 20 minutes. One group received low dose betahistine (0.01 mg/kg bw) and selegiline (1 mg/kg bw) i.v. while the other group received only selegiline (1 mg/kg bw) and saline (0.9% NaCl) as placebo i.v. Results: Cochlear microcirculation increased significantly ( P < .001) in guinea pigs treated with low dose betahistine combined with selegiline by up to 58.3 ± 38.7% above baseline over a period of up to 11 minutes. In one guinea pig, the increase was 104.6%. Treatment with Selegiline alone did not affect microcirculation significantly. Conclusions: Low dose betahistine increased cochlear microcirculation significantly when combined with selegiline. This should be investigated in further studies regarding dose-effect relation in comparison to betahistine alone. Side effects, in particular regarding circulation, should be considered carefully in view of the clinical applicability of a combination therapy in patients with MD.

Objectives: In human medicine, limb amputation affects caregiver psychosocial burden. This study assessed caregiver burden in owners of dogs following limb amputation. Materials and methods: From March to September 2024, owners of healthy dogs with limb loss (> 6 months) and owners of healthy dogs without limb amputation (control dogs) were recruited via veterinary clinics, physiotherapy practices, university hospitals and social media to complete an online questionnaire. The 115-item survey included general questions on daily life and validated instruments assessing caregiver burden and psychosocial functioning: Zarit Burden Interview (ZBI), Perceived Stress Scale, Center of Epidemiologic Studies Depression scale, Generalized Anxiety Disorder 7-Item Scale, Quality of Life Enjoyment and Satisfaction Questionnaire. Descriptive statistics and group comparisons (Chi-Squared, Mann–Whitney U test and Students t -test) were performed in R. Results: Seventy-six owners of dogs with limb amputation (hindlimb: n = 35; forelimb: n = 41) and 74 owners of control dogs completed the survey (90.7% women; 70.7% aged 19–49). ZBI and other scores did not differ significantly between groups. Caregiver demographics (age, gender, relationship status, profession, number of caregivers) and dog-related factors (age at amputation, reason, leg affected, size, weight, adoption status) showed no significant effect on ZBI-scores. Higher ZBI-scores were reported when dogs could no longer hike ( p = 0.05), and lower scores when caregivers received positive social feedback ( p = 0.02). Prosthesis use ( p = 0.02), low prosthesis acceptance ( p = 0.04) or use of assistive devices ( p = 0.02) were associated with higher caregiver burden. Conclusion: Most caregivers of canine amputees do not report elevated caregiver burden. However, functional changes in the dog and social or assistive factors were associated with caregiver experience.

Introduction: Extracorporeal shockwave therapy (ESWT) is used as an adjunctive treatment for canine osteoarthritis (OA), but its effects in dogs with treatment-refractory advanced disease remain unclear. This study compared the efficacy of one versus two sessions of focused ESWT administered approximately 28 days apart in dogs with refractory elbow or stifle OA. Methods: In this randomized, double-blinded clinical trial, twenty-four client-owned dogs with treatment-refractory elbow (n = 12) or stifle (n = 12) osteoarthritis received ESWT using an identical per-session protocol (X-Trode, 1000 pulses at 0.14 mJ/mm²; PulseVet-Zomedica, Ann Arbor, MI, USA), once (Group L) or twice (Group E). Orthopedic examination, goniometric and limb circumference measurements, and kinetic gait analysis (peak vertical pressure [PVP], vertical impulse [VI]) were performed on days 0, 28, and 56. Owner questionnaires (Canine Brief Pain Inventory [CBPI], Client Specific Outcome Measures [CSOM]) were collected on days 0, 28, 56, and 84. Data were analyzed using chi-squared tests, t-tests, and mixed effects models in R. Results: Age, weight, BCS, and radiographic osteoarthritis severity did not differ between groups at baseline. Improvement was small and limited to selected parameters. Vertical impulse and limb circumference increased more consistently in Group E, whereas peak vertical pressure increased in both groups, including before ESWT in Group L. No sustained or treatment-associated improvement was detected in symmetry variables or joint range of motion. Owner-reported outcomes showed variable patterns without consistent treatment effects. ESWT was well tolerated, and no major adverse events occurred. Conclusion: ESWT produced modest, inconsistent improvements in dogs with treatment-refractory OA, with slightly more consistent effects following two sessions. Therapeutic efficacy appeared limited in this end-stage population.

Various accelerometers offer to monitor sleep efficiency in dogs, but the underlying proprietary algorithms are not usually revealed. The aim of this pilot study was to achieve insights on the performance of an omnidirectional accelerometer to document sleeping and resting periods in dogs with a simple binary cut-off (0 cpm; ≥1 cpm) and the interference of movements. All data were acquired with a neck collar-mounted accelerometer (Actical^®; Philips Respironics Inc., Murrysville, PA, USA) that provides access to raw data. Ten privately owned dogs (6 dogs with and 4 dogs without movements during sleep) were monitored shortly before, during and after their sleeping and resting periods. Experienced observers documented any visible movement and the corresponding behavioral state continuously for each minute as apparent sleep (eyes closed, regular breathing pattern), rest (eyes open), awake and alert. Total observation time was 2633 min, and 32 sleeping and resting periods were monitored. Zero accelerometer counts per minute documented the combined sleeping and resting periods with a sensitivity of 94.0% and specificity of 96.1% but could not differentiate between apparent sleeping and resting with eyes closed or open. Mild movements during sleep did not interfere with the recordings. The pilot data obtained in this study supports further investigation of this approach to document sleeping and resting periods over prolonged periods in individual dogs.