Thanyani Pandelani

Prof. Dr. Thanyani Pandelani

University of South Africa, Pretoria, Gauteng, South Africa
+3

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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3 January 2020 in PLOS ONE
Verified
Journal Article
Open access
PDF file
CBColin J. Boyle
Colin J. Boyle
DCDiagarajen Carpanen
Diagarajen Carpanen
TPThanyani Pandelani
Thanyani Pandelani
CHClaire A. Higgins
Claire A. Higgins
MMMarc Masen
Marc Masen
SMSpyros D. Masouros
Spyros D. Masouros
When immobile or neuropathic patients are supported by beds or chairs, their soft tissues undergo deformations that can cause pressure ulcers. Current support surfaces that redistribute under-body pressures at vulnerable body sites have not succeeded in reducing pressure ulcer prevalence. Here we show that adding a supporting lateral pressure can counter-act the deformations induced by under-body pressure, and that this ‘pressure equalisation’ approach is a more effective way to reduce ulcer-inducing deformations than current approaches based on redistributing under-body pressure. A finite element model of the seated pelvis predicts that applying a lateral pressure to the soft tissue reduces peak von Mises stress in the deep tissue by a factor of 2.4 relative to a standard cushion (from 113 kPa to 47 kPa)—a greater effect than that achieved by using a more conformable cushion, which reduced von Mises stress to 75 kPa. Combining both a conformable cushion and lateral pressure reduced peak von Mises stresses to 25 kPa. The ratio of peak lateral pressure to peak under-body pressure was shown to regulate deep tissue stress better than under-body pressure alone. By optimising the magnitude and position of lateral pressure, tissue deformations can be reduced to that induced when suspended in a fluid. Our results explain the lack of efficacy in current support surfaces and suggest a new approach to designing and evaluating support surfaces: ensuring sufficient lateral pressure is applied to counter-act under-body pressure.

5 May 2022 in Heliyon
Verified
Journal Article
Open access
HNHarry Ngwangwa
Harry Ngwangwa
TPThanyani Pandelani
Thanyani Pandelani
MMMakhosasana Msibi
Makhosasana Msibi
IMIsrael Mabuda
Israel Mabuda
LSLetlhogonolo Semakane
Letlhogonolo Semakane
Fulufhelo NemavholaFulufhelo Nemavhola
Fulufhelo Nemavhola
High quality computational model of soft tissues is a function of accurate and reliable mechanical properties. Hyperelastic constitutive models are normally utilised in developing reliable computational models. Therefore, section of proper and reliable constitutive models for soft tissue is critical. This work presents the biomechanical properties of oesophagus subjected to biaxial mechanical tensile test. Additionally, six hyperelastic constitutive models commonly used for modelling behaviour of soft tissues were selected. The experimental data were then fitted on Fung, Choi-Vito, Holzapfel (2000), Holzapfel (2005), Polynomial (Anisotropic) and Four-Fiber Family hyperelastic constitutive models. The sheep oesophagus subjected to equi-biaxial tension has exhibited different stress magnitude in both longitudinal and circumferential directions. There is significant difference between circumferential and longitudinal stresses (p = 0.0034). The average circumferential and longitudinal stresses are recorded to be 82.87 ± 30.36 kPa and 41.42 ± 32.02 kPa, respectively (p = 0.0034). Between six hyperelastic constitutive models, it was observed that Four-Fiber model has produced better fit when compared to others. After fitting biaxial mechanical properties of oesophagus, it was found that the Four-fiber family hyperelastic constitutive model would best fit.

18 October 2025 in Journal of Biomechanics
Verified
Journal Article
Closed access
NFNele Famaey
Nele Famaey
HFHeleen Fehervary
Heleen Fehervary
YLYoann Lafon
Yoann Lafon
AAAli Akyildiz
Ali Akyildiz
SDSilke Dreesen
Silke Dreesen
LGLiesbet Geris
Liesbet Geris

24 March 2022 in Processes
Verified
Journal Article
Open access
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Harry M NgwangwaHarry M Ngwangwa
Harry M Ngwangwa
Fulufhelo NemavholaFulufhelo Nemavhola
Fulufhelo Nemavhola
TPThanyani Pandelani
Thanyani Pandelani
MMMakhosasana Msibi
Makhosasana Msibi
IMIsrael Mabuda
Israel Mabuda
TFThomas Franz
Thomas Franz
Heart myocardia are critical to the facilitation of heart pumping and blood circulating around the body. The biaxial mechanical testing of the left ventricle (LV) has been extensively utilised to build the computational model of the whole heart with little importance given to the unique mechanical properties of the right ventricle (RV) and cardiac septum (SPW). Most of those studies focussed on the LV of the heart and then applied the obtained characteristics with a few modifications to the right side of the heart. However, the assumption that the LV characteristics applies to the RV has been contested over time with the realisation that the right side of the heart possesses its own unique mechanical properties that are widely distinct from that of the left side of the heart. This paper evaluates the passive mechanical property differences in the three main walls of the rat heart based on biaxial tensile test data. Fifteen mature Wistar rats weighing 225 ± 25 g were euthanised by inhalation of 5% halothane. The hearts were excised after which all the top chambers comprising the two atria, pulmonary and vena cava trunks, aorta, and valves were all dissected out. Then, 5 × 5 mm sections from the middle of each wall were carefully dissected with a surgical knife to avoid overly pre-straining the specimens. The specimens were subjected to tensile testing. The elastic moduli, peak stresses in the toe region and stresses at 40% strain, anisotropy indices, as well as the stored strain energy in the toe and linear region of up to 40% strain were used for statistical significance tests. The main findings of this study are: (1) LV and SPW tissues have relatively shorter toe regions of 10–15% strain as compared to RV tissue, whose toe region extends up to twice as much as that; (2) LV tissues have a higher strain energy storage in the linear region despite being lower in stiffness than the RV; and (3) the SPW has the highest strain energy storage along both directions, which might be directly related to its high level of anisotropy. These findings, though for a specific animal species at similar age and around the same body mass, emphasise the importance of the application of wall-specific material parameters to obtain accurate ventricular hyperelastic models. The findings further enhance our understanding of the desired mechanical behaviour of the different ventricle walls.

28 February 2022 in Applied Bionics and Biomechanics
Verified
Journal Article
Open access
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ZNZwelihle Ndlovu
Zwelihle Ndlovu
Dawood DesaiDawood Desai
Dawood Desai
TPThanyani Pandelani
Thanyani Pandelani
Harry M NgwangwaHarry M Ngwangwa
Harry M Ngwangwa
Fulufhelo NemavholaFulufhelo Nemavhola
Fulufhelo Nemavhola
This study assesses the modelling capabilities of four constitutive hyperelastic material models to fit the experimental data of the porcine sclera soft tissue. It further estimates the material parameters and discusses their applicability to a finite element model by examining the statistical dispersion measured through the standard deviation. Fifteen sclera tissues were harvested from porcine’ slaughtered at an abattoir and were subjected to equi-biaxial testing. The results show that all the four material models yielded very good correlations at correlations above 96%. The polynomial (anisotropic) model gave the best correlation of 98%. However, the estimated material parameters varied widely from one test to another such that there would be need to normalise the test data to avoid long optimisation processes after applying the average material parameters to finite element models. However, for application of the estimated material parameters to finite element models, there would be need to consider normalising the test data to reduce the search region for the optimisation algorithms. Although the polynomial (anisotropic) model yielded the best correlation, it was found that the Choi-Vito had the least variation in the estimated material parameters, thereby making it an easier option for application of its material parameters to a finite element model and requiring minimum effort in the optimisation procedure. For the porcine sclera tissue, it was found that the anisotropy was more influenced by the fiber-related properties than the background material matrix-related properties.

26 April 2025 in Sustainability
Verified
Journal Article
Open access
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MAMariam Iyabo Adeoba
Mariam Iyabo Adeoba
TPThanyani Pandelani
Thanyani Pandelani
Harry M NgwangwaHarry M Ngwangwa
Harry M Ngwangwa
TMTracy Madimabi Masebe
Tracy Madimabi Masebe
The application of artificial intelligence (AI) in monitoring and managing ocean waste reveals considerable promise for improving sustainable strategies to combat marine pollution. This study performs a bibliometric analysis to examine research trends, knowledge frameworks, and future directions in AI-driven sustainable ocean waste management. This study delineates key research themes, prominent journals, influential authors, and leading nations contributing to the field by analysing scientific publications from major databases. Research from citation networks, keyword analysis, and co-authorship patterns highlights significant topics such as AI algorithms for waste detection, machine learning models for predictive mapping of pollution hotspots, and the application of autonomous drones and underwater robots in real-time waste management. The findings indicate a growing global focus on utilising AI to enhance environmental monitoring, optimise waste reduction methods, and support policy development for sustainable marine ecosystems. This bibliometric study provides a comprehensive analysis of the current knowledge landscape, identifies research gaps, and underscores the importance of AI as a crucial enabler for sustainable ocean waste management, offering vital insights for researchers, industry leaders, and environmental policymakers dedicated to preserving ocean health.