Kohei Iwatsuki

Mr. Kohei Iwatsuki


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 November 2021 in Sensors
Verified
Journal Article
Open access
PDF file
YYYuichi Yoshida
Yuichi Yoshida
XDXue Ding
Xue Ding
KIKohei Iwatsuki
Kohei Iwatsuki
KTKatsuya Taniizumi
Katsuya Taniizumi
HIHirofumi Inoue
Hirofumi Inoue
Toshihiko KiwaToshihiko Kiwa
Toshihiko Kiwa
Cancer genome analysis has recently attracted attention for personalized cancer treatment. In this treatment, evaluation of the ratio of cancer cells in a specimen tissue is essential for the precise analysis of the genome. Conventionally, the evaluation takes at least two days and depends on the skill of the pathologist. In our group, a terahertz chemical microscope (TCM) was developed to easily and quickly measure the number of cancer cells in a solution. In this study, an antibody was immobilized on a sensing plate using an avidin-biotin reaction to immobilize it for high density and to improve antibody alignment. In addition, as the detected terahertz signals vary depending on the sensitivity of the sensing plate, the sensitivity was evaluated using pH measurement. The result of the cancer cell detection was corrected using the result of pH measurement. These results indicate that a TCM is expected to be an excellent candidate for liquid biopsies in cancer diagnosis.