This comprehensive scientific review provides an in-depth analysis of both the natural compounds, pyrethrins, and their synthetic derivatives, pyrethroids, focusing on their classification, biosynthesis, mechanism of action, general and pharmaceutical uses, as well as their toxicity and environmental impact. Pyrethrins, derived from certain plant species, have long been recognized for their potent insecticidal properties. The review begins by examining the classification of pyrethrins and pyrethroids, elucidating their structural characteristics and unique features within the field of natural and synthetic compounds. The biosynthetic pathways responsible for producing pyrethrins in plants are discussed, highlighting the enzymatic reactions and genetic regulation involved. In addition, the synthesis of pyrethroid derivatives is explored, including both natural and synthetic sources and potential optimization strategies. Understanding the mechanisms of action by which pyrethrins and pyrethroids exert their insecticidal effects is a crucial aspect of this review. Complex interactions with the nervous systems of target organisms are examined, providing insights into their selective toxicity and modes of action. In addition, the various applications of these compounds are explored, from their use in agriculture for pest control to their incorporation into household insecticides and potential pharmaceutical applications. The review also critically evaluates the potential toxicity of pyrethrins and pyrethroids to human health. By consolidating current knowledge and research findings, this review provides a comprehensive understanding of the properties and applications of pyrethrins and pyrethroids, highlighting their benefits and risks, and the importance of responsible and sustainable use in various areas.

This comprehensive scientific review provides an in-depth analysis of both the natural compounds, pyrethrins, and their synthetic derivatives, pyrethroids, focusing on their classification, biosynthesis, mechanism of action, general and pharmaceutical uses, as well as their toxicity and environmental impact. Pyrethrins, derived from certain plant species, have long been recognized for their potent insecticidal properties. The review begins by examining the classification of pyrethrins and pyrethroids, elucidating their structural characteristics and unique features within the field of natural and synthetic compounds. The biosynthetic pathways responsible for producing pyrethrins in plants are discussed, highlighting the enzymatic reactions and genetic regulation involved. In addition, the synthesis of pyrethroid derivatives is explored, including both natural and synthetic sources and potential optimization strategies. Understanding the mechanisms of action by which pyrethrins and pyrethroids exert their insecticidal effects is a crucial aspect of this review. Complex interactions with the nervous systems of target organisms are examined, providing insights into their selective toxicity and modes of action. In addition, the various applications of these compounds are explored, from their use in agriculture for pest control to their incorporation into household insecticides and potential pharmaceutical applications. The review also critically evaluates the potential toxicity of pyrethrins and pyrethroids to human health. By consolidating current knowledge and research findings, this review provides a comprehensive understanding of the properties and applications of pyrethrins and pyrethroids, highlighting their benefits and risks, and the importance of responsible and sustainable use in various areas.

This research provides a comprehensive evaluation of the phytochemical composition, antioxidant potential, and biological properties of four plant species with longstanding use in ethnobotanical traditions: Calendula officinalis, Mentha × piperita, Urtica dioica, and Juglans regia. Plant extracts were obtained using a range of solvent systems and subsequently analyzed for their content of total polyphenols, flavonoids, and phenolic acids. Ultra-high-performance liquid chromatography coupled with mass spectrometry (UHPLC-MS) enabled the accurate identification and quantification of major polyphenolic constituents. The antioxidant capacity was assessed through a series of in vitro assays, and elemental analysis was conducted to determine microelement content. To evaluate potential ecological implications, acute toxicity was tested using Daphnia magna, while phytotoxic effects were also examined. The results demonstrate pronounced antioxidant activity along with notable biocidal and soil-enhancing properties. These findings underscore the potential of such plant-based formulations as sustainable alternatives to conventional agrochemicals and highlight the relevance of integrating traditional botanical knowledge with modern strategies for enhancing soil quality, crop performance, and environmental sustainability.

Raising animals at the household level occupies an important place in the rural economy, providing families with a relatively constant income and a source of food. The demand for organic products of animal origin, the prohibition or limitation use of medicinal substances for various treatments and and the search for alternatives to feed additives, are the key factors that determine the pursuit for natural solutions to increase milk production. Herbal spices can influence the way animals are fed and ultimately have the beneficial effect of stimulating the level of secretory tissue of the mammary gland, which would result in an improvement in milk production. The paper aims to contribute to the review of various studies on galactogenic plants with effect on milk production. The study considered the follow-up of research published in the last few years. Galactogenic plants have triggered a special interest because of their availability, low cost and no toxic residues left in milk. Phyto-pharmacological research on medicinal plants can contribute to the discovery of some new ways of using galactogenic plants in the diet of dairy animals. Following the bibliographic study carried out in the paper, it was established that there are several milk-producing species that can be fed galactogenic effect plants (cows, goats, sheep, buffaloes) and there are a series of medicinal plants more common in making feed mixtures in order to stimulate the growth of milk production (Asparagus racemosus, Trigonella foenum-graecum, Cuminum cyminum, Carum carvi, Nigella sativa). Researches about natural alternatives to increase milk production in dairy animals is still limited. It is necessary to carry out further studies about plants with a galactogenic effect on the physiology of milk production in livestock species.

The purpose of this study was to develop a complex composition of a foliar liquid mineral fertilizer containing NPK macroelements and microelements including Fe, Mg, B, S, Zn, Cu, Mo, Ni, V, and Cr. This complex fertilizer aims to support the optimal development and maturation of maize crops, thereby enhancing both the quality and quantity of production. In our study, an original recipe was established for a complex composition of foliar liquid mineral fertilizer, and a technological process was developed in order to obtain the recipe at the laboratory level. The designed fertilizer was a complex mixture of fertilizers with herbicides with multiple purposes, which can be used in different pedo-climatic areas and which present, at the same time, low toxicity and minimal ecological impact. A wide-spectrum mixture DICOPUR TOP containing 2,4-D acid and Dicamba was chosen as a systemic herbicide which is absorbed by plants both in the root system and also on the leaves. For conditioning the complex mixture of fertilizers with herbicides, different types of polyvinyl alcohol with different degrees of hydrolysis were used. The liquid fertilizer mixture with DICOPUR TOP was applied over two years (2021 and 2022) to the Felix maize hybrid, demonstrating significant positive effects on grain yield while effectively controlling both dicotyledonous and monocotyledonous weeds.

Background: This study is a part of an ample research concerning the genetic history of Hucul horse breed. The genetic analysis studies are part of animal genetic resources Management because just start of them we elaborate the strategies for inbreeding management. The itself genetic relationship of a population is the average genetic relationship of all individuals between them, existing at a time. Therefore, this parameter can be described three components: the genetic relationship between stallions, between mother mares themselves and the genetic relationship between stallions and mares. The last component is most important because of the average population inbreeding increases in successive generations. Methods: The research was carried out during 2012-2020. The material are represented by genealogical information from reproductive nucleus of Hucul breed from Lucina studfarm. The sample extracted from population was represented by seven sire stallions and seventy-three broodmares. The method are based on A matrix coefficients. All analysis were performed in the profile laboratories of Animal Sciences Faculties from Bucharest and Timisoara. Result: Between individual average genetic relationship values of stallions with mares, is found significant differences, highlighted by the global test of homogeneity test (F = 4.891). These differences allow us to assert that, through stallions selection, is made a reproductive discrimination much more intense than in mares case. The average genetic relationship of the population was calculated at 0.1941±0.0053.