Antonio Nardone

Prof. Antonio Nardone

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Research Focus & Metrics

Academic Career Length

43Years (1984-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 April 2010 in Journal of Rehabilitation Medicine
Verified
Journal Article
Open access
FFF Franchignoni
F Franchignoni
FHF Horak
F Horak
MGMarco Godi
Marco Godi
Antonio NardoneAntonio Nardone
Antonio Nardone
AGA Giordano
A Giordano
Objective: To improve, with the aid of psychometric analysis, the Balance Evaluation Systems Test (B...

1 February 1989 in The Journal of Physiology
Verified
Journal Article
Closed access
PDF file
Antonio NardoneAntonio Nardone
Antonio Nardone
CRC Romanò
C Romanò
MSMarco Schieppati
Marco Schieppati

1 February 2013 in Physical Therapy
Verified
Journal Article
Open access
PDF file
MGMarco Godi
Marco Godi
FFFranco Franchignoni
Franco Franchignoni
MCMarco Caligari
Marco Caligari
AGAndrea Giordano
Andrea Giordano
ATAnna Maria Turcato
Anna Maria Turcato
Antonio NardoneAntonio Nardone
Antonio Nardone
Background: Recently, a new tool for assessing dynamic balance impairments has been presented: the 14-item Mini-BESTest. Objective: The aim of this study was to compare the psychometric performance of the Mini-BESTest and the Berg Balance Scale (BBS). Design: A prospective, single-group, observational design was used in the study. Methods: Ninety-three participants (mean age=66.2 years, SD=13.2; 53 women, 40 men) with balance deficits were recruited. Interrater (3 raters) and test-retest (1–3 days) reliability were calculated using intraclass correlation coefficients (ICCs). Responsiveness and minimal important change were assessed (after 10 sessions of physical therapy) using both distribution-based and anchor-based methods (external criterion: the 15-point Global Rating of Change [GRC] scale). Results: At baseline, neither floor effects nor ceiling effects were found in either the Mini-BESTest or the BBS. After treatment, the maximum score was found in 12 participants (12.9%) with BBS and in 2 participants (2.1%) with Mini-BESTest. Test-retest reliability for total scores was significantly higher for the Mini-BESTest (ICC=.96) than for the BBS (ICC=.92), whereas interrater reliability was similar (ICC=.98 versus .97, respectively). The standard error of measurement (SEM) was 1.26 and the minimum detectable change at the 95% confidence level (MDC95) was 3.5 points for Mini-BESTest, whereas the SEM was 2.18 and the MDC95 was 6.2 points for the BBS. In receiver operating characteristic curves, the area under the curve was 0.92 for the Mini-BESTest and 0.91 for the BBS. The best minimal important change (MIC) was 4 points for the Mini-BESTest and 7 points for the BBS. After treatment, 38 participants evaluated with the Mini-BESTest and only 23 participants evaluated with the BBS (out of the 40 participants who had a GRC score of ≥3.5) showed a score change equal to or greater than the MIC values. Limitations: The consecutive sampling method drawn from a single rehabilitation facility and the intrinsic weakness of the GRC for calculating MIC values were limitations of the study. Conclusions: The 2 scales behave similarly, but the Mini-BESTest appears to have a lower ceiling effect, slightly higher reliability levels, and greater accuracy in classifying individual patients who show significant improvement in balance function.

1 August 1997 in Electroencephalography and Clinical Neurophysiology/Electromyography and Motor Control
Verified
Journal Article
Closed access
Antonio NardoneAntonio Nardone
Antonio Nardone
JTJessica Tarantola
Jessica Tarantola
AGAndrea Giordano
Andrea Giordano
MSMarco Schieppati
Marco Schieppati

1 June 1991 in Brain
Verified
Journal Article
Closed access
PDF file
MSMarco Schieppati
Marco Schieppati
Antonio NardoneAntonio Nardone
Antonio Nardone
Upright stance and its reflex control were studied in parkinsonian patients and in age-matched normal subjects. They stood unperturbed on a force-measuring surface (static conditions), or were displaced by movement of a supporting platform (dynamic conditions). During quiet stance the following variables were analysed, with eyes open or closed: position of the centre of foot pressure (CFP), average sway area, length of sway path, amplitude and distribution of tonic leg muscle EMG activity. Perturbations of stance were induced by toe-up or toe-down rotations, and by backward or forward translations of the platform. Amplitude of short, medium and long-latency EMG responses to displacement were measured in the tibialis anterior (TA) and in the three heads of the triceps surae (TS) muscle. The perturbations were produced during both free and supported stance (holding onto a stable structure), under which condition normal subjects suppress medium and long-latency responses. Under static conditions, the only significant finding in parkinsonians was represented by a shift in the position of the CFP. This was correlated with the severity of the disease (Webster scale), the less affected patients being shifted backwards and the more affected patients forwards, with respect to normals. Under dynamic conditions, the reflex responses to perturbations of free stance were similar in both groups. Only the medium-latency burst of gastrocnemius lateralis and the long-latency burst TA evoked by TS stretch were larger in parkinsonians. The amplitude of these responses, as well as of all the others, was not related to the Webster score. Within the patients' group, a relationship between position of CFP and area of EMG burst was found for both medium and long-latency TA responses evoked by forward translation and toe-up rotation, respectively. Under supported conditions, the capability to suppress all medium and long-latency muscle responses to any perturbation was lost or impaired in the parkinsonians. The degree of impairment was unrelated to the position of the CFP, but was significantly related to the severity of the disease. The suppression to 40%(supported/nonsupported), of TA response to toe-down rotation is proposed as the point of separation between normals and parkinsonians. The forward projection of the CFP, occurring in the severe stages of the disease, and the increase in amplitude of some responses to perturbations of free stance might be a compensatory adaptation to the anomalous upright posture. The inappropriate reduction of the late responses during supported stance is considered as a sign of failure of motor program selection, possibly connected with a disorder of the supplementary motor area.

8 July 2013 in Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Verified
Journal Article
Closed access
MCMarco Caligari
Marco Caligari
MGMarco Godi
Marco Godi
SGSimone Guglielmetti
Simone Guglielmetti
FFFranco Franchignoni
Franco Franchignoni
Antonio NardoneAntonio Nardone
Antonio Nardone
People with amyotrophic lateral sclerosis (PwALS) show progressive loss of voluntary muscle strength. In advanced disease, motor and phonatory impairments seriously hinder the patient's interpersonal communication. High-tech devices such as eye tracking communication devices (ETCDs) are used to aid communication in the later stages of ALS. We sought to evaluate the effect of ETCDs on patient disability, quality of life (QoL), and user satisfaction, in a group of 35 regular ETCD users in late-stage ALS with tetraplegia and anarthria. The following scales were administered: 1) the Individually Prioritized Problem Assessment (IPPA) scale, in three conditions: without device, with ETCD and, when applicable, with an Eye Transfer (ETRAN) board; 2) the Psychosocial Impact of Assistive Devices Scale (PIADS); and 3) the Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST 2.0). With ETRAN, IPPA showed an increase in communicative abilities with respect to the condition without device, but ETCD produced a further significant increase. PIADS evidenced a large increase of QoL, and QUEST 2.0 showed high user satisfaction with ETCD use. In conclusion, ETCDs should be considered in late-stage ALS with tetraplegia and anarthria, since in these patients they can reduce communication disability and improve QoL.