Herein, a sodium alginate/poly (acrylic acid)/oxidized-multi-walled carbon nanotubes hydrogel nanocomposite (SA/p(AAc)/o-MWCNTs HNC) was synthesized by in situ free-radical polymerization method. The synthesized SA/p(AAc)/o-MWCNTs HNC was used to remove methylene blue (MB) from aqueous solution. The synthesized HNC was confirmed by employing various characterization techniques. The SA/p(AAc)/o-MWCNTs HNC exhibited a maximum swelling capacity of 2265.4% at pH 8.0. The influence of vital parameters in the sorption process including the initial pH, adsorption dose, contact time and concentration were systematically examined on a batch mode. Subsequently, adsorption kinetics as well as isotherm models were applied to assess the nature and mechanism of the adsorption process. Adsorption kinetics were best described by pseudo-second-order model, while the Langmuir isotherm model governed the adsorption isotherm. The SA/p(AAc)/o-MWCNTs HNC exhibited a maximum adsorption capacity of 1596.0 mg/g at 25°C. This adsorbent showed excellent MB uptake and good regeneration ability.

Globally, cancer is affecting societies and is becoming an important cause of death. Chemotherapy can be highly effective, but it is associated with certain problems, such as undesired targeting and multidrug resistance. The other advanced therapies, such as gene therapy and peptide therapy, do not prove to be effective without a proper delivery medium. Polymer-based hybrid nanoarchitectures have enormous potential in drug delivery. The polymers used in these nanohybrids (NHs) provide them with their distinct properties and also enable the controlled release of the drugs. This review features the recent use of polymers in the preparation of different nanohybrids for cancer therapy published since 2015 in some reputed journals. The polymeric nanohybrids provide an advantage in drug delivery with the controlled and targeted delivery of a payload and the irradiation of cancer by chemotherapeutical and photodynamic therapy.