Background: Hand tremor typically has a negative impact on a person’s ability to complete many common daily activities. Previous research has investigated how to quantify hand tremor with smartphones and wearable sensors, mainly under controlled data collection conditions. Solutions for daily real-life settings remain largely underexplored. Objective: Our objective was to monitor and assess hand tremor severity in patients with Parkinson disease (PD), and to better understand the effects of PD medications in a naturalistic environment. Methods: Using the Welch method, we generated periodograms of accelerometer data and computed signal features to compare patients with varying degrees of PD symptoms. Results: We introduced and empirically evaluated the tremor intensity parameter (TIP), an accelerometer-based metric to quantify hand tremor severity in PD using smartphones. There was a statistically significant correlation between the TIP and self-assessed Unified Parkinson Disease Rating Scale (UPDRS) II tremor scores (Kendall rank correlation test: z=30.521, P<.001, τ=0.5367379; n=11). An analysis of the “before” and “after” medication intake conditions identified a significant difference in accelerometer signal characteristics among participants with different levels of rigidity and bradykinesia (Wilcoxon rank sum test, P<.05). Conclusions: Our work demonstrates the potential use of smartphone inertial sensors as a systematic symptom severity assessment mechanism to monitor PD symptoms and to assess medication effectiveness remotely. Our smartphone-based monitoring app may also be relevant for other conditions where hand tremor is a prevalent symptom.

Mobile and tablet apps, ubiquitous and pervasive computing, wearable computing and domotics for health.

Future smart cities are expected to provide intelligent services such as predictions, detections, and automation through digital twins. However, the creation of digital twins requires the processing of an enormous amount of data, thereby leading to an increase in mobile network traffic. This traffic is produced by applications in user devices and city services, which engage in local consumption at the city scale through sensor and camera devices using mobile networks. Such increased traffic can compromise the communication speed and stability. To alleviate this burden, traffic offloading becomes a crucial consideration in the beyond-5G era. This paper presents a scheme known as Area-Controlled Mobile Ad-Hoc Networking (AMoND). AMoND uses a hierarchical structure of a location layer and an ad-hoc layer to construct area-controlled mobile ad-hoc networks (MANETs) for mutual support of the digital twin and MANETs. AMoND effectively suppresses mobile network traffic by harnessing the digital twin to assist the MANETs during data collection for the digital twin construction. Importantly, the digital twin used in AMoND focuses on the management of node location information and does not need to reproduce the real space on a computer fully. AMoND is not dependent on a specific MANET protocol and can be used as an add-on. AMoND exhibits the ability to reduce traffic volumes by up to approximately 65%, while maintaining arrival rates that are comparable to existing MANET protocols under certain conditions.