Background: The eruption of the first permanent molar (FPM) marks the beginning of the mixed dentition, which is one of the most dynamic periods in the development and growth of the stomatognathic system. Aim: The purpose of the study was to investigate the pathology of the first permanent molar (FPM) during the transition stage between the primary and permanent dentition. Materials and Methods: A literature search was performed in Clarivate Web of Science, Google Scholar, and PubMed databases. Cohort and cross-sectional studies, reviews, case reports, background information, and expert opinion were included. Results: Ectopic eruption is one of the most frequent pathologies during the mixed dentition period, and ectopic eruption of the maxillary FPM is the most encountered. Hypomineralization is currently the most prevalent pathology of the hard dental tissue in FPM, often in association with the same type of damage on the incisors in the context of the so-called molar incisor hypomineralization (MIH). FPM particular vulnerability to caries is due to its posteruptive enamel maturation, which is accomplished during the mixed dentition stage. Conclusions: Proper clinical management of FPM pathology is a demanding task for the pediatric dentist and is of great importance for the development of a healthy permanent dentition and stable occlusion.

The articular eminence (AE) is part of the temporal component of the temporomandibular joint (TMJ). The inclination of the AE (AEI) has an important role in TMJ biodynamics, influencing the path of movement of the disc–condyle complex. Although AEI values might change due to tooth loss, little is known about what effect could have the loss of occlusal support in the molar area on AE morphology. AEI was measured on cone-beam computed tomography (CBCT) images of 41 patients (82 TMJs) with or without occlusal support in the molar region. The patients included in this study were divided into four groups: (1) patients with maintained occlusal support in the molar areas on both sides (right and left side) (MM); (2) patients with loss of occlusal support in the molar areas on both sides (right and left side) (LL); (3) patients with loss of occlusal support in the molar area only on the right side, but with maintained occlusal support on the left molar area (LM); (4) patients with loss of occlusal support in the molar area only on the left side, but with maintained occlusal support in the right molar area (ML). AEI values were higher in the TMJs on the side with maintained occlusal support in the molar area (M) than the AEI values measured in TMJs from the side with loss of occlusal support in the molar area (L). AEI values on the right side were higher in the MM patients in comparison to the AEI values on the right side of LL patients. The loss of occlusal support in the molar areas changes the mandibular biodynamics, which might be reflected in the morphological changes at the AE level, where it might cause flattening of the articular slope predominantly on the right side.

Background/Objectives: Among the paranasal sinuses, the maxillary antrum holds unique clinical relevance due to its proximity to the alveolar process of the maxilla, which houses the teeth. This study aimed to evaluate the position of the root apices of the maxillary canines and posterior teeth relative to the maxillary sinus floor in Romanian subjects. Methods: Data for the study were retrospectively obtained from cone-beam computed tomography (CBCT) scans. The evaluation considered the pattern of proximity to the sinus floor for each tooth type, comparisons of the sinus relationships of teeth within the same dental hemiarch, as well as those of homologous teeth, and variation in root-to-sinus distance in relation to sex and age. Nonparametric tests were used for statistical analysis, and multiple comparisons were performed using Bonferroni post hoc correction. Results: The study included 70 individuals aged 20 to 60 years. The distance to the sinus floor decreased progressively from the first premolar to the second molar, with median values of 3.68 mm (first premolar), 1.45 mm (second premolar), 0.50 mm (first molar), and 0.34 mm (second molar) (p < 0.01). Stronger correlations were observed between adjacent teeth than between non-adjacent ones. The distances to the sinus floor were greater on the right side compared to the left; however, these differences were not statistically significant (p > 0.05 for all teeth). Concordance between left and right dental hemiarches regarding the closest tooth to the sinus floor was found in 70% of cases (n = 49), most frequently involving the second molars (n = 38; 54.3%). On average, the distance from the sinus floor was smaller in males compared to females, with statistically significant differences observed only for the second molar. Increased age was associated with a greater distance to the sinus floor. Conclusions: Of all the teeth investigated, the second molar showed the highest combined prevalence of penetrating and tangential relationships with the maxillary sinus. At the dental hemiarch level, the second molar was most frequently the closest tooth to the sinus floor, and in the majority of cases, at least one posterior tooth was located within 0.3 mm. Accurate preoperative assessment of tooth position relative to the sinus floor is essential when performing non-surgical or surgical root canal therapy and extractions of maxillary molars and premolars. CBCT provides essential three-dimensional imaging that improves diagnostic precision and supports safer treatment planning for procedures involving the posterior maxilla.

(1) Background: Salvation surgery for small-cell lung cancer (SCLC) is exceptionally performed, and only a few cases are published. (2) Methods: There are 6 publications that present 17 cases of salvation surgery for SCLC—the salvation surgery was performed in the context of modern clearly established protocols for SCLC and after including SCLC in the TNM (tumor, node, metastasis) staging in 2010. (3) Results: After a median follow-up of 29 months, the estimated overall survival (OS) was 86 months. The median estimated 2-year survival was 92%, and the median estimated 5-year survival was 66%. (4) Conclusion: Salvage surgery for SCLC is a relatively new and extremely uncommon concept and represents an alternative to second-line chemotherapy. It is valuable because it may offer a reasonable treatment for selected patients, good local control, and a favorable survival outcome.

The widespread use of advanced imaging techniques has led to a rising incidence of adrenal incidentalomas (AIs), asymptomatic adrenal masses discovered during imaging for non-adrenal-related conditions. AIs represent a diagnostic and therapeutic challenge due to their varied etiology, secretory potential, and potential for malignancy. This review aims to provide a comprehensive overview of the current knowledge on adrenal incidentalomas, focusing on their pathogenesis, diagnostic work-up, imaging features, hormonal evaluation, and evidence-based management, with a special emphasis on autonomous cortisol secretion (ACS). A thorough narrative review of the literature from the past two decades was conducted, synthesizing data from key international guidelines (ESE/ENSAT), observational studies, meta-analyses, and case series regarding the evaluation and treatment of AI. AI represents an increasingly relevant clinical condition requiring a multidisciplinary, personalized approach. Prompt endocrine and radiological evaluation is essential to identify hormonally active or potentially malignant tumors. The complexity of the natural history of AI and the evolving understanding of ACS underline the need for tailored follow-up and management strategies.

Background/Objectives: Artificial intelligence (AI) is increasingly used in dental diagnostics, treatment planning, documentation, and research. However, there is limited synthesis of how informed consent should be understood and operationalized in AI-augmented dentistry. This scoping review aimed to map the existing literature on informed consent in AI-assisted dental care and dental research, identify conceptual and practical gaps, and synthesize key domains relevant to ethically robust implementation. Methods: This review was conducted in accordance with PRISMA-ScR and the review question was developed using the Population–Concept–Context framework. Searches were performed in PubMed, Web of Science, and ClinicalKey, supplemented by Google Scholar and reference list screening. English-language sources published between January 2015 and January 2026 were considered if they addressed informed consent, patient information, autonomy, transparency, accountability, or governance in relation to AI use in dentistry or dental research. Results: Of 2624 records identified, 30 sources were included. The reviewed literature consistently emphasized the importance of disclosing AI involvement, clarifying clinician accountability, communicating uncertainty and bias, distinguishing clinical care from research-related consent, and addressing secondary data use. Most included sources were conceptual, ethical, regulatory, or narrative in nature, with limited empirical evidence on implementation or patient outcomes. Conclusions: The available literature suggests that informed consent in AI-augmented dentistry should extend beyond traditional clinician–patient models to explicitly address AI involvement, human oversight, and data governance. Based on recurring themes across the included sources, we propose the ACCOUNT-AI framework as a conceptual synthesis to support future research, policy development, and implementation efforts.