The Internet of Things confers seamless connectivity between people and objects, and its confluence with the Cloud improves our lives. Predictive analytics in the medical domain can help turn a reactive healthcare strategy into a proactive one, with advanced artificial intelligence and machine learning approaches permeating the healthcare industry. As the subfield of ML, deep learning possesses the transformative potential for accurately analysing vast data at exceptional speeds, eliciting intelligent insights, and efficiently solving intricate issues. The accurate and timely prediction of diseases is crucial in ensuring preventive care alongside early intervention for people at risk. With the widespread adoption of electronic clinical records, creating prediction models with enhanced accuracy is key to harnessing recurrent neural network variants of deep learning possessing the ability to manage sequential time-series data. The proposed system acquires data from IoT devices, and the electronic clinical data stored on the cloud pertaining to patient history are subjected to predictive analytics. The smart healthcare system for monitoring and accurately predicting heart disease risk built around Bi-LSTM (bidirectional long short-term memory) showcases an accuracy of 98.86%, a precision of 98.9%, a sensitivity of 98.8%, a specificity of 98.89%, and an F-measure of 98.86%, which are much better than the existing smart heart disease prediction systems.

Cloud computing has become integral lately due to the ever-expanding Internet-of-things (IoT) network. It still is and continues to be the best practice for implementing complex computational applications, emphasizing the massive processing of data. However, the cloud falls short due to the critical constraints of novel IoT applications generating vast data, which entails a swift response time with improved privacy. The newest drift is moving computational and storage resources to the edge of the network, involving a decentralized distributed architecture. The data processing and analytics perform at proximity to end-users, and overcome the bottleneck of cloud computing. The trend of deploying machine learning (ML) at the network edge to enhance computing applications and services has gained momentum lately, specifically to reduce latency and energy consumed while optimizing the security and management of resources. There is a need for rigorous research efforts oriented towards developing and implementing machine learning algorithms that deliver the best results in terms of speed, accuracy, storage, and security, with low power consumption. This extensive survey presented on the prominent computing paradigms in practice highlights the latest innovations resulting from the fusion between ML and the evolving computing paradigms and discusses the underlying open research challenges and future prospects.

The ongoing fast-paced technology trend has brought forth ceaseless transformation. In this regard, cloud computing has long proven to be the paramount deliverer of services such as computing power, software, networking, storage, and databases on a pay-per-use basis. The cloud is a big proponent of the internet of things (IoT), furnishing the computation and storage requisite to address internet-of-things applications. With the proliferating IoT devices triggering a continual data upsurge, the cloud–IoT interaction encounters latency, bandwidth, and connectivity restraints. The inclusion of the decentralized and distributed fog computing layer amidst the cloud and IoT layer extends the cloud’s processing, storage, and networking services close to end users. This hierarchical edge–fog–cloud model distributes computation and intelligence, yielding optimal solutions while tackling constraints like massive data volume, latency, delay, and security vulnerability. The healthcare domain, warranting time-critical functionalities, can reap benefits from the cloud–fog–IoT interplay. This research paper propounded a fog-assisted smart healthcare system to diagnose heart or cardiovascular disease. It combined a fuzzy inference system (FIS) with the recurrent neural network model’s variant of the gated recurrent unit (GRU) for pre-processing and predictive analytics tasks. The proposed system showcases substantially improved performance results, with classification accuracy at 99.125%. With major processing of healthcare data analytics happening at the fog layer, it is observed that the proposed work reveals optimized results concerning delays in terms of latency, response time, and jitter, compared to the cloud. Deep learning models are adept at handling sophisticated tasks, particularly predictive analytics. Time-critical healthcare applications reap benefits from deep learning’s exclusive potential to furnish near-perfect results, coupled with the merits of the decentralized fog model, as revealed by the experimental results.