Monica Macrì

Prof. Monica Macrì

University of Chieti-Pescara, Chieti, Italy
orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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20 June 2023 in Biomedicines
Verified
Journal Article
Open access
PDF file
FFFelice Festa
Felice Festa
SMSilvia Medori
Silvia Medori
MMMonica Macrì
Monica Macrì
While the physical improvements from exercise have been well documented over the years, the impact of physical activity on mental health has recently become an object of interest. Physical exercise improves cognition, particularly attention, memory, and executive functions. However, the mechanisms underlying these effects have yet to be fully understood. Consequently, we conducted a narrative literature review concerning the association between acute and chronic physical activity and cognition to provide an overview of exercise-induced benefits during the lifetime of a person. Most previous papers mainly reported exercise-related greater expression of neurotransmitter and neurotrophic factors. Recently, structural and functional magnetic resonance imaging techniques allowed for the detection of increased grey matter volumes for specific brain regions and substantial modifications in the default mode, frontoparietal, and dorsal attention networks following exercise. Here, we highlighted that physical activity induced significant changes in functional brain activation and cognitive performance in every age group and could counteract psychological disorders and neural decline. No particular age group gained better benefits from exercise, and a specific exercise type could generate better cognitive improvements for a selected target subject. Further research should develop appropriate intervention programs concerning age and comorbidity to achieve the most significant cognitive outcomes.

11 February 2022 in Frontiers in Materials
Verified
Journal Article
Open access
MMMonica Macrì
Monica Macrì
GMGiovanna Murmura
Giovanna Murmura
GVGiuseppe Varvara
Giuseppe Varvara
TTTonino Traini
Tonino Traini
FFFelice Festa
Felice Festa
In recent years, aesthetic concerns regarding orthodontic appliances have significantly increased due to the growing number of adult patients undergoing orthodontic therapy. Clear removable aligners have seen growing popularity as an aesthetic and comfortable alternative to traditional fixed appliances. Clear aligner therapy also appears more respectful of the patient’s periodontal health; in fact, clear aligners allow the patients to maintain proper daily oral hygiene thanks to being removable. Among the parameters that affect the clinical efficacy of aligners, the material employed for their manufacturing plays a key role. The present paper aims to review the most used materials in manufacturing clear aligners, focusing on their clinical and mechanical performances, according to the current state of literature. Furthermore, biological features of the different materials are also examined regarding their effects on dental and periodontal tissues, oral mucosa, and potential systemic effects.

31 July 2024 in Bioengineering
Verified
Journal Article
Open access
PDF file
MMMonica Macrì
Monica Macrì
VDVincenzo D’Albis
Vincenzo D’Albis
Giuseppe D'AlbisGiuseppe D'Albis
Giuseppe D'Albis
MFMarta Forte
Marta Forte
Saverio CapodiferroSaverio Capodiferro
Saverio Capodiferro
FFFelice Festa
Felice Festa
Artificial intelligence (AI) is revolutionizing dentistry, offering new opportunities to improve the precision and efficiency of implantology. This literature review aims to evaluate the current evidence on the use of AI in implant planning assessment. The analysis was conducted through PubMed and Scopus search engines, using a combination of relevant keywords, including “artificial intelligence implantology”, “AI implant planning”, “AI dental implant”, and “implantology artificial intelligence”. Selected articles were carefully reviewed to identify studies reporting data on the effectiveness of AI in implant planning. The results of the literature review indicate a growing interest in the application of AI in implant planning, with evidence suggesting an improvement in precision and predictability compared to traditional methods. The summary of the obtained findings by the included studies represents the latest AI developments in implant planning, demonstrating its application for the automated detection of bones, the maxillary sinus, neuronal structure, and teeth. However, some disadvantages were also identified, including the need for high-quality training data and the lack of standardization in protocols. In conclusion, the use of AI in implant planning presents promising prospects for improving clinical outcomes and optimizing patient management. However, further research is needed to fully understand its potential and address the challenges associated with its implementation in clinical practice.

23 August 2024 in Materials
Verified
Journal Article
Open access
PDF file
MMMonica Macrì
Monica Macrì
VDVincenzo D’Albis
Vincenzo D’Albis
RMRaffaele Marciani
Raffaele Marciani
MNMatteo Nardella
Matteo Nardella
FFFelice Festa
Felice Festa
The increasing concern over environmental sustainability has prompted various industries to reassess their practices and explore greener alternatives. Dentistry, as a significant contributor to waste generation, is actively seeking methods to minimize its environmental footprint. This paper examines the environmental implications of clear aligner therapy (CAT) in orthodontics and explores strategies to prioritize sustainability in aligner manufacturing and usage. CAT has gained popularity as a viable alternative to traditional fixed appliances due to advancements in biomaterials and computer-aided design (CAD) and manufacturing (CAM) technologies. The global market for clear aligners is expanding rapidly, with significant growth projected in the coming years. To address these challenges, this paper proposes adopting the principles of reduce, reuse, recycle, and rethink (4Rs) in orthodontic practices. Strategies such as minimizing resource consumption, incorporating recycled materials, and promoting proper aligner disposal and recycling can significantly reduce environmental harm. This paper explores emerging technologies and materials to mitigate the environmental impacts of CAT. Additionally, initiatives promoting aligner recycling and repurposing offer promising avenues for reducing plastic waste and fostering a circular economy. In conclusion, while CAT offers numerous benefits in orthodontic treatment, its environmental impact cannot be overlooked. By implementing sustainable practices and embracing innovative solutions, the orthodontic community can contribute to a more environmentally conscious future while continuing to provide quality care to patients.

12 April 2021 in Frontiers in Neurology
Verified
Journal Article
Open access
FFFelice Festa
Felice Festa
CRChiara Rotelli
Chiara Rotelli
ASAntonio Scarano
Antonio Scarano
RNRiccardo Navarra
Riccardo Navarra
MCMassimo Caulo
Massimo Caulo
MMMonica Macrì
Monica Macrì
Myofascial pain in the masticatory region, generally referred to as headache, is a common temporomandibular disorder (TMD) characterized by the hypersensitive regions of the contracted skeletal muscle fibers. A correct clinical treatment of myofascial pain has the potential to modify the functional activation of cerebral networks associated with pain and unconscious teeth clenching, specifically the pain network (PN) and default mode network (DMN). In this study, research is presented as a case series of five patients with myofascial pain: three were diagnosed with intra- and extra-articular disorders, and two were diagnosed with only extra-articular disorders. All five patients received gnathological therapy consisting of passive splints and biofeedback exercises for tongue–palatal vault coordination. Before and after treatment, patients underwent pain assessments (through measures of visual analog scales and muscular palpation tests), nuclear magnetic resonance of the temporomandibular joint, and functional nuclear magnetic resonance of the brain. In each patient, temporomandibular joint nuclear magnetic resonance results were similar before and after the gnathological treatment. However, the treatment resulted in a considerable reduction in pain for all patients, according to the visual analog scales and the palpation test. Furthermore, functional nuclear magnetic resonance of the brain clearly showed a homogeneous modification in cerebral networks associated with pain (i.e., PN and DMN), in all patients. In conclusion, gnathological therapy consisting of passive aligners and biofeedback exercises improved myofascial pain in all five patients. Most importantly, this study showed that all five patients had a homogeneous functional modification of pain and default mode networks. Using passive splints in combination with jaw exercises may be an effective treatment option for patients with TMD. This research could be a starting point for future investigations and for clinicians who want to approach similar situations.

Verified
Journal Article
Open access
PDF file
MMMonica Macrì
Monica Macrì
GDGiuseppe D’albis
Giuseppe D’albis
VDVincenzo D’albis
Vincenzo D’albis
AAAnna Antonacci
Anna Antonacci
AAAntonia Abbinante
Antonia Abbinante
FFFelice Festa
Felice Festa
Background: Studies suggest that chronic psychological stress can lead to oral health deterioration, alter the immune response, and possibly contribute to increased inflammation, which can impact the physiological healing of periodontal tissues. This cross-sectional study seeks to assess and improve clinical understanding regarding the relationship between perceived stress, mindfulness, and periodontal health. Methods: A total of 203 people were analyzed from December 2022 to June 2023. The Periodontal Screening and Recording (PSR) score and Gingival Bleeding Index (GBI), and Plaque Control Record (PCR) of every patient were registered. Subsequently, participants completed the Sheldon Cohen Perceived Stress Scale (PSS) and the Mindfulness Awareness Attention Scale (MAAS) questionnaires. The collected data underwent statistical analysis, encompassing the evaluation of correlations and dependencies. Applying Welch’s t-test to assess the relationship between MAAS and the variable indicating the presence or absence of periodontitis, a noteworthy p-value of 0.004265 was obtained. Results: This underscores a significant distinction in MAAS scores between patients affected by periodontitis and those unaffected by the condition. Additionally, Pearson correlations were computed for GBI and perceived stress, PCR and perceived stress, PCR and MAAS. The resulting p-values of 2.2–16, 3.925–8, and 2.468–8, respectively, indicate a statistically significant correlation in each instance. Conclusions: These findings contribute valuable insights into the interconnectedness of these variables, emphasizing the significance of their associations in the study context. Despite the limitations, the findings of this study suggest a significant relationship between psychological stress, mindfulness, and periodontal tissue health. Clinical trials are necessary to incorporate the assessment of a patient’s psychological status as a new valuable tool in the management of periodontal health.