Dr. Irina Fierascu
1. National Institute for Research & Development in Chemistry and Petrochemistry - ICECHIM, Bucharest, Romania
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Academic Career Length
15Years (2012-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications15 April 2020 in Frontiers in Bioengineering and Biotechnology
Journal Article
RFRadu C. Fierascu
Radu C. Fierascu
Elwira SieniawskaAOAlina Ortan
Alina Ortan
Irina FierascuJXJianbo Xiao
Jianbo Xiao
The growing demand for more sustainable, alternative processes leading to production of plant-derived preparations imposes the use of plants waste generated mainly by agri-food and pharmaceutical industries. These mostly unexploited but large quantities of plants waste also increase the interest in developing alternative approaches for sustainable production of therapeutic molecules. In order to reduce the amount of plant waste by further processing, different novel extraction techniques can be applied. Fruits and their industrial by-products are rich sources of different classes of compounds with therapeutic properties. The processed fruits waste can be reused and lead to novel pharmaceuticals, food supplements or functional foods. This review intends to briefly summarize recent aspects regarding the production of different active compounds from fruit by-products, and their therapeutic properties. The potential use of fruits by-products in different industries will be also discussed.
Journal Article
Radu Claudiu FierascuIrina Fierascu
avramescu sorinElwira SieniawskaLarge amounts of agro-industrial waste are being generated each year, leading to pollution and economic loss. At the same time, these side streams are rich source of active compounds including antioxidants. Recovered compounds can be re-utilized as food additives, functional foods, nutra-/pharmaceuticals, cosmeceuticals, beauty products, and bio-packaging. Advanced extraction techniques are promising tools to recover target compounds such as antioxidants from agro-industrial side streams. Due to the disadvantages of classical extraction techniques (such as large amounts of solvents, increased time of extraction, large amounts of remaining waste after the extraction procedure, etc.), and advanced techniques emerged, in order to obtain more efficient and sustainable processes. In this review paper aspects regarding different modern extraction techniques related to recovery of antioxidant compounds from wastes generated in different industries and their applications are briefly discussed.
Journal Article
Radu Claudiu FierascuIrina FierascuABAnda Baroi
Anda BaroiAOALINA ORTAN
ALINA ORTANNatural compounds obtained from different medicinal and aromatic plants have gained respect as alternative treatments to synthetic drugs, as well as raw materials for different applications (cosmetic, food and feed industries, environment protection, and many others). Based on a literature survey on dedicated databases, the aim of the present work is to be a critical discussion of aspects regarding classical extraction versus modern extraction techniques; possibilities to scale up (advantages and disadvantages of different extraction methods usually applied and the influence of extraction parameters); and different medicinal and aromatic plants’ different applications (medical and industrial applications, as well as the potential use in nanotechnology). As nowadays, research studies are directed toward the development of modern, innovative applications of the medicinal and aromatic plants, aspects regarding future perspectives are also discussed.
Journal Article
Irina FierascuCDCristina Elena Dinu-Pîrvu
Cristina Elena Dinu-PîrvuRadu Claudiu Fierascu
Bruno Stefan VelescuVAValentina Anuta
Valentina Anuta
Viorel Jinga +1
Satureja hortensis L. (summer savory) is an annual herbaceous crop, native to Europe and in our days spread and used all over the world. Although its use as spice and medicinal plant is known since ancient times, peer-reviewed studies presenting the scientific data are scarce. The natural products obtained from summer savory (extracts and essential oil) are dominated by polyphenols and flavonoids, responsible for their antioxidant, antimicrobial, antiparasitic, pesticidal, anti-inflammatory, analgesic, hepatoprotective and anticancer properties, among others. The current study presents the progress made in the last decade regarding the potential applications of summer savory, being the first review study focused on S. hortensis, in the same time suggesting future research opportunities, as they appear from the properties of other Satureja species. The available data presenting the properties of summer savory represents a scientific support for application in industry, for developing “clean label” food products.
Journal Article
ABAnda Maria Baroi
Anda Maria BaroiMPMircea Popitiu
Mircea PopitiuIrina FierascuISIonela Daniela Sărdărescu
Ionela Daniela SărdărescuRadu Claudiu FierascuWine production is one of the most critical agro-industrial sectors worldwide, generating large amounts of waste with negative environmental impacts, but also with high economic value and several potential applications. From wine shoots to grape pomace or seeds, all of the wastes are rich sources of bioactive compounds with beneficial effects for human health, with these compounds being raw materials for other industries such as the pharmaceutical, cosmetic or food industries. Furthermore, these compounds present health benefits such as being antioxidants, supporting the immune system, anti-tumoral, or preventing cardiovascular and neural diseases. The present work aims to be a critical discussion of the extraction methods used for bioactive compounds from grapevine waste and their beneficial effects on human health.
Journal Article
Radu Claudiu FierascuIrina FierascuAOALINA ORTAN
ALINA ORTAN
Milen I. GeorgievElwira SieniawskaContinuously growing demand for plant derived therapeutic molecules obtained in a sustainable and eco-friendly manner favors biotechnological production and development of innovative extraction techniques to obtain phytoconstituents. What is more, improving and optimization of alternative techniques for the isolation of high value natural compounds are issues having both social and economic importance. In this critical review, the aspects regarding plant biotechnology and green downstream processing, leading to the production and extraction of increased levels of fine chemicals from both plant cell, tissue, and organ culture or fresh plant materials and the remaining by-products, are discussed.
About Me
Irina Fierăscu is a scientific researcher (CS1) at INCDCP-ICECHIM Bucharest with competencies in analytical chemistry (different modern analytical techniques), nanomaterials (obtaining and characterization), nanotechnology, materials science, archaeometry, superior use of natural resources (obtaining and using natural extracts), photosynthesized nanomaterials, environmental protection, etc. Her Ph.D. is in Material Engineering, and she has followed postdoctoral programs in Industrial Biotechnology and Environmental Engineering. Her habilitation thesis covers “Capitalization of autochthonous vegetal species: from biomedical applications to nanotechnology”. She is the author/co-author of several papers published in prestigious ISI journals (more than 80) in the field of natural extracts, nanomaterials, and photosynthesized metallic nanoparticles (especially gold and silver nanoparticles), as well as
the author/co-author of 12 books/chapter in books. She has experience in managing projects with topics of international relevance and the application of nanomaterials in different fields: environment, agriculture or conservation/restoration of cultural heritage artifacts. She has won different awards from government
institutions or other prestigious institutions in the field.