Radu Claudiu Fierascu

Prof. Dr. Radu Claudiu Fierascu

National Institute for Research & Development in Chemistry and Petrochemistry – ICECHIM Bucharest, Emerging Nanotechnologies Group Bucharest, Romania
orcid

Research Focus & Metrics

Academic Career Length

18Years (2009-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 August 2017 in Polymers
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Journal Article
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Stefan Ovidiu DimaStefan Ovidiu Dima
Stefan Ovidiu Dima
DPDenis Mihaela Panaitescu
Denis Mihaela Panaitescu
COCsongor Orban
Csongor Orban
MGMarius Ghiurea
Marius Ghiurea
SDSanda Maria Doncea
Sanda Maria Doncea
Florin OanceaFlorin Oancea
Florin Oancea
We focused on preparing cellulose nanofibrils by purification, separation, and mechanical treatment of Kombucha membranes (KM) resulted as secondary product from beverage production by fermentation of tea broth with symbiotic culture of bacteria and yeast (SCOBY). We purified KM using two alkaline solutions, 1 and 4 M NaOH, which afterwards were subjected to various mechanical treatments. Transmission electron microscopy (TEM), scanning electron microscopy (SEM), dynamic light scattering (DLS), X-ray diffraction (XRD), X-ray fluorescence (XRF), Fourier-transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA) were employed to evaluate the purification degree, the size and aspect of cellulose fibrils after each treatment step, the physical-chemical properties of intermediary and final product, and for comparison with micro-crystalline cellulose from wooden sources. We determined that 1 M NaOH solution leads to approx. 85% purification, while a higher concentration assures almost 97% impurities removal. XRD analysis evidenced an increase in crystallinity from 37% to 87% after purification, the characteristic diffractograms of Iα and Iβ cellulose allomorphs, and a further decrease in crystallinity to 46% after microfluidization, fact correlated with a drastically decrease in fibrils’ size. FTIR analysis evidenced the appearance of new chain ends by specific transmission bands at 2941 and 2843cm−1.

20 November 2019 in Molecules
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Radu Claudiu FierascuRadu Claudiu Fierascu
Radu Claudiu Fierascu
Irina FierascuIrina Fierascu
Irina Fierascu
avramescu sorinavramescu sorin
avramescu sorin
Elwira SieniawskaElwira Sieniawska
Elwira Sieniawska
Large amounts of agro-industrial waste are being generated each year, leading to pollution and economic loss. At the same time, these side streams are rich source of active compounds including antioxidants. Recovered compounds can be re-utilized as food additives, functional foods, nutra-/pharmaceuticals, cosmeceuticals, beauty products, and bio-packaging. Advanced extraction techniques are promising tools to recover target compounds such as antioxidants from agro-industrial side streams. Due to the disadvantages of classical extraction techniques (such as large amounts of solvents, increased time of extraction, large amounts of remaining waste after the extraction procedure, etc.), and advanced techniques emerged, in order to obtain more efficient and sustainable processes. In this review paper aspects regarding different modern extraction techniques related to recovery of antioxidant compounds from wastes generated in different industries and their applications are briefly discussed.

Verified
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Radu Claudiu FierascuRadu Claudiu Fierascu
Radu Claudiu Fierascu
Irina FierascuIrina Fierascu
Irina Fierascu
ABAnda Baroi
Anda Baroi
AOALINA ORTAN
ALINA ORTAN
Natural compounds obtained from different medicinal and aromatic plants have gained respect as alternative treatments to synthetic drugs, as well as raw materials for different applications (cosmetic, food and feed industries, environment protection, and many others). Based on a literature survey on dedicated databases, the aim of the present work is to be a critical discussion of aspects regarding classical extraction versus modern extraction techniques; possibilities to scale up (advantages and disadvantages of different extraction methods usually applied and the influence of extraction parameters); and different medicinal and aromatic plants’ different applications (medical and industrial applications, as well as the potential use in nanotechnology). As nowadays, research studies are directed toward the development of modern, innovative applications of the medicinal and aromatic plants, aspects regarding future perspectives are also discussed.

25 September 2018 in Molecules
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Irina FierascuIrina Fierascu
Irina Fierascu
CDCristina Elena Dinu-Pîrvu
Cristina Elena Dinu-Pîrvu
Radu Claudiu FierascuRadu Claudiu Fierascu
Radu Claudiu Fierascu
Bruno Stefan VelescuBruno Stefan Velescu
Bruno Stefan Velescu
VAValentina Anuta
Valentina Anuta
Viorel JingaViorel Jinga
Viorel Jinga
Satureja hortensis L. (summer savory) is an annual herbaceous crop, native to Europe and in our days spread and used all over the world. Although its use as spice and medicinal plant is known since ancient times, peer-reviewed studies presenting the scientific data are scarce. The natural products obtained from summer savory (extracts and essential oil) are dominated by polyphenols and flavonoids, responsible for their antioxidant, antimicrobial, antiparasitic, pesticidal, anti-inflammatory, analgesic, hepatoprotective and anticancer properties, among others. The current study presents the progress made in the last decade regarding the potential applications of summer savory, being the first review study focused on S. hortensis, in the same time suggesting future research opportunities, as they appear from the properties of other Satureja species. The available data presenting the properties of summer savory represents a scientific support for application in industry, for developing “clean label” food products.

15 February 2022 in Antioxidants
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ABAnda Maria Baroi
Anda Maria Baroi
MPMircea Popitiu
Mircea Popitiu
Irina FierascuIrina Fierascu
Irina Fierascu
ISIonela Daniela Sărdărescu
Ionela Daniela Sărdărescu
Radu Claudiu FierascuRadu Claudiu Fierascu
Radu Claudiu Fierascu
Wine production is one of the most critical agro-industrial sectors worldwide, generating large amounts of waste with negative environmental impacts, but also with high economic value and several potential applications. From wine shoots to grape pomace or seeds, all of the wastes are rich sources of bioactive compounds with beneficial effects for human health, with these compounds being raw materials for other industries such as the pharmaceutical, cosmetic or food industries. Furthermore, these compounds present health benefits such as being antioxidants, supporting the immune system, anti-tumoral, or preventing cardiovascular and neural diseases. The present work aims to be a critical discussion of the extraction methods used for bioactive compounds from grapevine waste and their beneficial effects on human health.

12 January 2020 in Molecules
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Journal Article
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Radu Claudiu FierascuRadu Claudiu Fierascu
Radu Claudiu Fierascu
Irina FierascuIrina Fierascu
Irina Fierascu
AOALINA ORTAN
ALINA ORTAN
Milen I. GeorgievMilen I. Georgiev
Milen I. Georgiev
Elwira SieniawskaElwira Sieniawska
Elwira Sieniawska
Continuously growing demand for plant derived therapeutic molecules obtained in a sustainable and eco-friendly manner favors biotechnological production and development of innovative extraction techniques to obtain phytoconstituents. What is more, improving and optimization of alternative techniques for the isolation of high value natural compounds are issues having both social and economic importance. In this critical review, the aspects regarding plant biotechnology and green downstream processing, leading to the production and extraction of increased levels of fine chemicals from both plant cell, tissue, and organ culture or fresh plant materials and the remaining by-products, are discussed.