Aquatic environments are one of the final destinations for microplastics. In this review, a combination of systematic and narrative literature review was conducted to identify and summarise advances, gaps, and future directions in microplastic monitoring studies in the Turkish aquatic environment and in inhabiting aquatic organisms. A total of 62 peer-reviewed publications available on Web of Science were considered in the systematic review. Additionally, the current state of microplastic pollution in Turkish aquatic environments which includes marine and freshwater ecosystems, as well as aquatic organisms, and sources and characteristics of microplastics were reviewed narratively. Türkiye`s position on the global plastic treaty and mitigation practices were also addressed. Although an increase in the number of publications over time was observed, the number and extent of studies carried out in freshwater ecosystems are limited. Strict legislation should be enacted and enforced to tackle plastic pollution in Türkiye. Additionally, nationwide, long-term monitoring studies at sufficiently regular intervals in aquatic environments should be considered.

Due to global warming, drought, population growth and industrialisation, existing water resources are rapidly being depleted and polluted. Pollution caused by millions of plastic waste reaching water resources seriously threatens the aquatic environment. This manuscript reviews the current state of knowledge about microplastics in the aquatic ecosystem, their analysis and detection methods, and their effects on aquatic organisms. In addition to the measurement methods, alternative new methods and the relevant findings for MPs, including abundance, size, shapes, colours and polymer types are summarised considering the literature. In addition, the effects of microplastics on the aquatic ecosystem especially fish had been evaluated. In the light of the completed researches, it is understood that abundance and size of MP s are connected with fish species, tissue type and feeding regime. KOH for the digestion in tissues and fenton reagent for sediment samples were found as more suitable techniques. FTIR and Raman spectroscopy were more advantaged because they are not only fast – easy but also have repeatable specifications.

Genetic, neuropathological and biochemical investigations have revealed meaningful relationships between aluminum (Al) exposure and neurotoxic and hematotoxic damage. Hence, intensive efforts are being made to minimize the harmful effects of Al. Moreover, boron compounds are used in a broad mix of industries, from cosmetics and pharmaceuticals to agriculture. They affect critical biological functions in cellular events and enzymatic reactions, as well as endocrinal and mineral metabolisms. There are limited dose-related data about boric acid (BA) and other boron compounds, including colemanite (Col), ulexite (UX) and borax (BX), which have commercial prominence. In this study, we evaluate boron compounds’ genetic, cytological, biochemical and pathological effects against aluminum chloride (AlCl₃)-induced hematotoxicity and neurotoxicity on different cell and animal model systems. First, we perform genotoxicity studies on in vivo rat bone marrow cells and peripheric human blood cultures. To analyze DNA and chromosome damage, we use single cell gel electrophoresis (SCGE or comet assay) and micronucleus (MN) and chromosome aberration (CA) assays. The nuclear division index (NDI) is used to monitor cytostasis. Second, we examine the biochemical parameters (superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), malondialdehyde (MDA), total antioxidant capacity (TAC) and total oxidative status (TOS)) to determine oxidative changes in blood and brain. Next, we assess the histopathological alterations by using light and electron microscopes. Our results show that Al increases oxidative stress and genetic damage in blood and brain in vivo and in vitro studies. Al also led to severe histopathological and ultrastructural alterations in the brain. However, the boron compounds alone did not cause adverse changes based on the above-studied parameters. Moreover, these compounds exhibit different levels of beneficial effects by removing the harmful impact of Al. The antioxidant, antigenotoxic and cytoprotective effects of boron compounds against Al-induced damage indicate that boron may have a high potential for use in medical purposes in humans. In conclusion, our analysis suggests that boron compounds (especially BA, BX and UX) can be administered to subjects to prevent neurodegenerative and hematological disorders at determined doses.