Sebastian Winklhofer

Dr. Sebastian Winklhofer


Research Focus & Metrics

Academic Career Length

15Years (2012-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 March 2014 in European Radiology
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Journal Article
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SWSebastian Winklhofer
Sebastian Winklhofer
ESEddie Surer
Eddie Surer
GAGaryfalia Ampanozi
Garyfalia Ampanozi
TRThomas Ruder
Thomas Ruder
PSPaul Stolzmann
Paul Stolzmann
WSWolf Schweitzer
Wolf Schweitzer

30 June 2022 in Skeletal Radiology
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Journal Article
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LWLucas Wolharn
Lucas Wolharn
RGRoman Guggenberger
Roman Guggenberger
KHKai Higashigaito
Kai Higashigaito
TSThomas Sartoretti
Thomas Sartoretti
SWSebastian Winklhofer
Sebastian Winklhofer
TFTim Finkenstaedt
Tim Finkenstaedt
Objectives: To compare the value of zero echo time (ZTE) and gradient echo “black bone” (BB) MRI sequences for bone assessment of the sacroiliac joint (SI) using computed tomography (CT) as the reference standard. Materials and methods: Between May 2019 and January 2021, 79 patients prospectively underwent clinically indicated 3-T MRI including ZTE and BB imaging. Additionally, all patients underwent a CT scan covering the SI joints within 12 months of the MRI examination. Two blinded readers performed bone assessment by grading each side of each SI joint qualitatively in terms of seven features (osteophytes, subchondral sclerosis, erosions, ankylosis, joint irregularity, joint widening, and gas in the SI joint) using a 4-point Likert scale (0 = no changes–3 = marked changes). Scores were compared between all three imaging modalities. Results: Interreader agreement was largely good (k values: 0.5–0.83). Except for the feature “gas in SI joint” where ZTE exhibited significantly lower scores than CT (p < 0.001), ZTE and BB showed similar performance relative to CT for all other features (p > 0.52) with inter-modality agreement being substantial to almost perfect (Krippendorff’s alpha coefficients: 0.724–0.983). When combining the data from all features except for gas in the SI joint and when binarizing grading scores, combined sensitivity/specificity was 76.7%/98.6% for ZTE and 80.8%/99.1% for BB, respectively, compared to CT. Conclusions: The performance of ZTE and BB sequences was comparable to CT for bone assessment of the SI joint. These sequences may potentially serve as an alternative to CT yet without involving exposure to ionizing radiation.

22 January 2018 in Neuroradiology
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SWSebastian Winklhofer
Sebastian Winklhofer
RHRicarda Hinzpeter
Ricarda Hinzpeter
DSDaniel Stocker
Daniel Stocker
GBGerasimos Baltsavias
Gerasimos Baltsavias
LMLars Michels
Lars Michels
HAHatem Alkadhi
Hatem Alkadhi

10 September 2021 in Diagnostics
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AHAdib Al-Haj Husain
Adib Al-Haj Husain
MSMark Solomons
Mark Solomons
BSBernd Stadlinger
Bernd Stadlinger
RPRada Pejicic
Rada Pejicic
SWSebastian Winklhofer
Sebastian Winklhofer
SVSilvio Valdec
Silvio Valdec
We evaluate the preoperative visualization of the inferior alveolar nerve (IAN) and lingual nerve (LN) as reported using radiation-free magnetic resonance imaging (MRI). An accurate visualization shall minimize the postoperative risk for nerve injuries in oral and maxillofacial surgery. PubMed MEDLINE, EMBASE, Biosis, and Cochrane databases were selected for the PICOS search strategy by two reviewers using medical subject headings (MeSH) terms. Thirty studies were included in the systematic review. Based on these studies’ findings, the use of black bone MRI sequences, especially 3D short-tau inversion recovery (STIR), provides superior soft-tissue resolution and high sensitivity in detecting pathological changes. Due to the implementation variability regarding scan parameters and the use of different magnetic field strengths, studies with well-designed protocols and a low risk of bias should be conducted to obtain stronger evidence. With improved cost and time efficiency and considering the benefit–risk ratio, MRI is a promising imaging modality that could become part of routine clinical practice in the future.

31 October 2013 in Forensic Science, Medicine and Pathology
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SWSebastian Winklhofer
Sebastian Winklhofer
NBNicole Berger
Nicole Berger
TRThomas Ruder
Thomas Ruder
MEMarina Elliott
Marina Elliott
PSPaul Stolzmann
Paul Stolzmann
GAGaryfalia Ampanozi
Garyfalia Ampanozi

22 June 2016 in European Spine Journal
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Journal Article
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SWSebastian Winklhofer
Sebastian Winklhofer
UHUlrike Held
Ulrike Held
JBJakob M. Burgstaller
Jakob M. Burgstaller
TFTim Finkenstaedt
Tim Finkenstaedt
NBNicolae Bolog
Nicolae Bolog
FGFilippo Del Grande
Filippo Del Grande