Photocatalysis plays a prominent role in the protection of the environment from recalcitrant pollutants by reducing hazardous wastes. Among the different methods of choice, photocatalysis mediated through nanomaterials is the most widely used and economical method for removing pollutants from wastewater. Recently, worldwide researchers focused their research on eco-friendly and sustainable environmental aspects. Wastewater contamination is one of the major threats coming from industrial processes, compared to other environmental issues. Much research is concerned with the advanced development of technology for treating wastewater discharged from various industries. Water treatment using photocatalysis is prominent because of its degradation capacity to convert pollutants into non-toxic biodegradable products. Photocatalysts are cheap, and are now emerging slowly in the research field. This review paper elaborates in detail on the metal oxides used as a nano photocatalysts in the various type of pollutant degradation. The progress of research into metal oxide nanoparticles, and their application as photocatalysts in organic pollutant degradation, were highlighted. As a final consideration, the challenges and future perspectives of photocatalysts were analyzed. The application of nano-based materials can be a new horizon in the use of photocatalysts in the near future for organic pollutant degradation.