Bartosz Lewandowski

Dr. Bartosz Lewandowski


Research Focus & Metrics

Academic Career Length

19Years (2008-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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28 February 2008 in Synthesis
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Journal Article
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SJSlawomir Jarosz
Slawomir Jarosz
BLBartosz Lewandowski
Bartosz Lewandowski
ALArkadiusz Listkowski
Arkadiusz Listkowski
Chiral macrocycles containing the sucrose skeleton were prepared by a ‘click chemistry’ route. The substrate for the Huisgen reaction was obtained from sucrose in eight steps. The 1,3-dipolar cycloaddition yielded the intramolecular as well as the C 2-symmetric macrocycles. Optimization of the reaction conditions allowed the preparation of both types of adducts with high selectivity and in good yields.

26 January 2023 in Nature Synthesis
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Journal Article
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BLBartosz Lewandowski
Bartosz Lewandowski
DSDario Schmid
Dario Schmid
RBRüdiger Borrmann
Rüdiger Borrmann
DZDominik Zetschok
Dominik Zetschok
MSMartin Schnurr
Martin Schnurr
HWHelma Wennemers
Helma Wennemers
Nature uses templated length-controlled oligomerization to process genetic information. Templates that are DNA and RNA based and fully synthetic have also been developed for preparing unnatural oligomers. However, these reactions require stoichiometric amounts of the template for product formation. Here we report a catalytic macrocyclic template that promotes the oligomerization of a small-molecule substrate with a remarkable degree of length control. The design of the template is based on rigid oligoproline moieties decorated with catalytic sites in a defined spatial arrangement. The dimension of the macrocycle and the number of catalytic moieties determine the number of monomers that are incorporated into the growing oligomer, thus allowing access to specific products with lengths preprogrammed by the template.

2 March 2021 in Chemical Communications
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PDPit Dominique
Pit Dominique
MSMartin Schnurr
Martin Schnurr
BLBartosz Lewandowski
Bartosz Lewandowski
Highly enantioselective binding of amino-acid esters in water by a small molecule receptor based on a glucose scaffold.

12 July 2009
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Book Chapter
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SJSlawomir Jarosz
Slawomir Jarosz
MMMarta Magdycz
Marta Magdycz
BLBartosz Lewandowski
Bartosz Lewandowski
The material reviewed in this paper covers only the last five years, with emphasis on the most recent results. It will not be comprehensive and will deal only with such transformations of simple sugars (and to some extent disaccharides), which lead to interesting optically pure compounds of (at leas...

19 February 2025 in Communications Chemistry
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MMMario M. Most
Mario M. Most
LBLinus B. Boll
Linus B. Boll
PGPeter Gödtel
Peter Gödtel
ZPZbigniew L. Pianowski
Zbigniew L. Pianowski
BLBartosz Lewandowski
Bartosz Lewandowski
Selective receptors of amino acids in aqueous media are highly sought after as they may enable the creation of novel diagnostic and sensing tools. Photoswitchable receptors are particularly attractive for such purposes as their response and selectivity towards bioanalytes can be modulated using light. Herein we report glucose-based photoswitchable receptors of amino-acid methyl esters and biogenic amines in water. The tetra-ortho-fluoroazobenzene unit in the receptors structure allows to control the distance between their binding sites using light. The Z-isomers of both receptors, having these sites in closer proximity, bind lysine, ornithine and arginine esters significantly stronger compared to E-isomers, where the binding sites are further apart.

8 November 2023 in Chemistry – A European Journal
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Journal Article
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SVSonia Vela‐Gallego
Sonia Vela‐Gallego
BLBartosz Lewandowski
Bartosz Lewandowski
JMJasper Möhler
Jasper Möhler
APAlonso Puente
Alonso Puente
DGDavid Gil‐Cantero
David Gil‐Cantero
AEAndres de la Escosura
Andres de la Escosura
Biohybrid catalysts that operate in aqueous media are intriguing for systems chemistry. In this paper, we investigate whether control over the self‐assembly of biohybrid catalysts can tune their properties. As a model, we use the catalytic activity of functional hybrid molecules consisting of a catalytic H‐dPro‐Pro‐Glu tripeptide, derivatized with fatty acid and nucleobase moieties. This combination of simple biological components merged the catalytic properties of the peptide with the self‐assembly of the lipid, and the structural ordering of the nucleobases. The biomolecule hybrids self‐assemble in aqueous media into fibrillar assemblies and catalyze the reaction between butanal and nitrostyrene. The interactions between the nucleobases enhanced the order of the supramolecular structures and affected their catalytic activity and stereoselectivity. The results point to the significant control and ordering that nucleobases can provide in the self‐assembly of biologically inspired supramolecular catalysts.