Capsules with shells based on nanoparticles of different nature co-assembled at the interface of liquid phases of emulsion are promising carriers of lipophilic drugs. To obtain such capsules, theoretically using the Derjaguin–Landau–Verwey–Overbeek (DLVO) theory and experimentally using dynamic light-scattering (DLS) and transmission electron microscopy (TEM) methods, the interaction of like-charged silica nanoparticles and detonation nanodiamonds in an aqueous solution was studied and their ratios selected for the formation of submicron-sized colloidosomes. The resulting colloidosomes were modified with additional layers of nanoparticles and polyelectrolytes, applying LbL technology. As a model anti-cancer drug, thymoquinone was loaded into the developed capsules, demonstrating a significant delay of the release as a result of colloidosome surface modification. Fluorescence flow cytometry and confocal laser scanning microscopy showed efficient internalization of the capsules by MCF7 cancer cells. The obtained results demonstrated a high potential for nanomedicine application in the field of the drug-delivery system development.

This paper submits experimental results of a study directed towards the formation of Eu ions’ luminescent centers in CVD diamond films. A new approach is based on use of diamond nanoparticles with a surface modified with Eu ions for seeding at CVD growth. Nanocrystalline diamond films (NCD) doped with Eu have been grown from the gas phase on silicon substrates by microwave plasma-assisted CVD at a frequency of 2.45 GHz. The photoluminescence spectra clearly show several electronic transitions of the Eu³⁺ ions, which confirm the incorporation of Eu ions into the NCD film.

Surface thermochemistry of detonation nanodiamonds (DND) is investigated by time-of-flight electron ionization mass-spectrometry. FTIR spectroscopy analysis supports mass-spectrometry results. The impact of ambient air atmosphere as part of DND deagglomeration process is revealed. It is stated that the surface of DND agglomerates is covered with esters, lactones, nitro-groups and aliphatic hydrocarbons. DND deagglomerated via annealing under air are terminated by carboxyl groups and carboxylic anhydrides. Carboxyl groups are revealed to be transformed to lactones during pyrolysis.