This research highlights that street layouts, including the vegetation ratio, street orientation, and aspect ratio, are key in diminishing urban heat islands (UHIs), building energy use, and carbon emissions. The optimal street layout for minimal building energy consumption, carbon emissions, and maximal outdoor thermal comfort in Tianjin was established via field measurements, ENVI-met 5.6.1, Energy Plus simulations, and correlation analysis. The findings indicate the following: (1) The carbon emissions of winter residential heating energy consumption are 2.9–3.2 times higher than those for summer cooling. Urban design should thus prioritize winter energy efficiency and summer thermal comfort outdoors. (2) The summer street PET (physiological equivalent temperature) inversely correlates with the vegetation ratio and aspect ratio. Winter heating energy use inversely correlates with the street orientation and directly correlates with the aspect ratio. Adequate vegetation and proper orientation can decrease energy and carbon output while enhancing summer outdoor comfort. (3) Streets with an NW–SE orientation, H/W = 0.9, and 50% trees in summer yield the best thermal comfort, while those with an NE–SW orientation, H/W = 0.3, and 50% vegetative trees in winter produce the lowest carbon emissions. These insights are instrumental in refining urban streets and building designs in cold zones.