Yun Ji Jung

Dr. Yun Ji Jung

orcid

Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2015 in Yonsei Medical Journal
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Journal Article
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Yun Ji JungYun Ji Jung
Yun Ji Jung
MKMin-A Kim
Min-A Kim
JKJa-Young Kwon
Ja-Young Kwon
HLHyo Ryun Lee
Hyo Ryun Lee
HCHee Young Cho
Hee Young Cho
YKYoung-Han Kim
Young-Han Kim
Jung YJ, et al. Yonsei Med J. 2015 May;56(3):793-797. http://dx.doi.org/10.3349/ymj.2015.56.3.793

Verified
Journal Article
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HKHayan Kwon
Hayan Kwon
Yun Ji JungYun Ji Jung
Yun Ji Jung
YLYeji Lee
Yeji Lee
GSGa-Hyun Son
Ga-Hyun Son
HKHyun Ok Kim
Hyun Ok Kim
JKJa-Young Kwon
Ja-Young Kwon
Maternal hyperglycemia, induced by gestational diabetes mellitus (GDM), has detrimental effects on fetal vascular development, ultimately increasing the risk of cardiovascular diseases in offspring. The potential underlying mechanisms through which these complications occur are due to functional impairment and epigenetic changes in fetal endothelial progenitor cells (EPCs), which remain less defined. We confirm that intrauterine hyperglycemia leads to the impaired angiogenic function of fetal EPCs, as observed through functional assays of outgrowth endothelial cells (OECs) derived from fetal EPCs of GDM pregnancies (GDM-EPCs). Notably, PCDH10 expression is increased in OECs derived from GDM-EPCs, which is associated with the inhibition of angiogenic function in fetal EPCs. Additionally, increased PCDH10 expression is correlated with the hypomethylation of the PCDH10 promoter. Our findings demonstrate that in utero exposure to GDM can induce angiogenic dysfunction in fetal EPCs through altered gene expression and epigenetic changes, consequently increasing the susceptibility to cardiovascular diseases in the offspring of GDM mothers.

14 May 2018 in American Journal of Reproductive Immunology
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Journal Article
Closed access
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Yun Ji JungYun Ji Jung
Yun Ji Jung
YPYejin Park
Yejin Park
HKHyun‐Soo Kim
Hyun‐Soo Kim
HLHwa Jin Lee
Hwa Jin Lee
YKYoo‐Na Kim
Yoo‐Na Kim
JKJa-Young Kwon
Ja-Young Kwon

1 January 2017 in Yonsei Medical Journal
Verified
Journal Article
Open access
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Yun Ji JungYun Ji Jung
Yun Ji Jung
HCHee Young Cho
Hee Young Cho
SCSiHyun Cho
SiHyun Cho
YKYoung-Han Kim
Young-Han Kim
JJJin-Dong Jeon
Jin-Dong Jeon
JKJa-Young Kwon
Ja-Young Kwon
Jung YJ, et al. Yonsei Med J. 2017 Mar;58(2):401-406. https://doi.org/10.3349/ymj.2017.58.2.401

1 January 2015 in Obstetrics & Gynecology Science
Verified
Journal Article
Open access
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Yun Ji JungYun Ji Jung
Yun Ji Jung
JKJa-Young Kwon
Ja-Young Kwon
HCHee Young Cho
Hee Young Cho
YPYong-Won Park
Yong-Won Park
YKYoung-Han Kim
Young-Han Kim
Jung YJ, et al. Obstet Gynecol Sci. 2015 Nov;58(6):439-445. http://dx.doi.org/10.5468/ogs.2015.58.6.439

Yun Ji JungYun Ji Jung
Yun Ji Jung
HKHayan Kwon
Hayan Kwon
JSJeongeun Shin
Jeongeun Shin
YPYejin Park
Yejin Park
SHSeok Jae Heo
Seok Jae Heo
JKJa-Young Kwon
Ja-Young Kwon
Previous studies demonstrated an association between cervical strain and risk of spontaneous preterm delivery (sPTD). The present study aimed to assess the efficacy of elastography in predicting sPTD at <32 weeks of gestation in women with singleton pregnancies receiving progesterone for short cervix (≤2.5 cm) diagnosed between 16 and 28 weeks of gestation Among 115 participants eligible for analysis, nine had sPTD at <32 weeks. Preprogesterone (PP0) mean internal os strain (IOS), elasticity contrast index (ECI), hardness ratio (HR), one-week postprogesterone (PP1) IOS, mean external os strain (EOS), ECI, and HR were significantly different between groups. Higher PP0 IOS, PP1 IOS, and PP1 EOS were associated with a 2.92, 4.39 and 3.65-fold increase in the risk of sPTD at <32 weeks, respectively (adjusted for cervical length (CL) at diagnosis; p = 0.04, 0.012 and 0.026, respectively). A combination of CL at diagnosis, PP0 IOS and PP1 EOS showed a significantly higher area under the receiver operating characteristic curve (0.858) than that of CL alone (p = 0.041). In women with singleton pregnancies receiving progesterone for short cervix, cervical elastography performed before and one week after progesterone treatment may be useful in predicting sPTD at <32 weeks of gestation.