Suicide is a worldwide public health problem. Evidence from previous studies has confirmed the relationship among anxiety, depression and suicidal ideation. However, the complex psychopathological pathways between anxiety and suicidal ideation and between depression and suicidal ideation require further study. A total of 505 college students from Shanghai during COVID-19 pandemic were investigated in an online study. Anxiety, depression and suicidal ideation of the participants were investigated. R software was used to construct the anxiety-suicidal ideation and depression-suicidal ideation networks and to evaluate the bridge expected influences. The anxiety-suicidal ideation network had 28 cross-community edges, the strongest one was A7 “Afraid something will happen”–S7 “Unable to solve personal problem”; A5 “Restlessness” and S3 “Hopelessness and suicide thoughts” had the highest bridge expected influences. The depression-suicidal ideation network had 36 cross-community edges, and the strongest one was D9 “Thoughts of death”–S5 “Unable to accomplish something important”; D9 “Thoughts of death” and S3 “Hopelessness and suicide thoughts” had the highest bridge expected influences. Intricate psychopathological pathways exist between anxiety and suicidal ideation and between depression and suicidal ideation. “Restlessness”, “Thoughts of death” and “Hopelessness and suicide thoughts” are considered targets for suicidal ideation interventions. The present study enriches the theory of symptoms and mental disorders and provides a reliable reference for the intervention practice of suicidal ideation.

(1) Background: The Go/NoGo task and color-word Stroop task were used to investigate the effect of applying different frequency bands of neural oscillations to the lDLPFC on inhibitory control modulation. (2) Methods: Participants were randomly categorized into four groups and received HD-tACS at 6, 10, and 20 Hz or sham stimulation at 1.5 mA for 20 min. All participants performed a color-word Stroop task and Go/NoGo task before and immediately after the stimulation; closed-eye resting-state EEG signals were acquired for 3 min before and after the tasks. (3) Results: There were no significant differences in the Go/NoGo behavioral indices task across the four groups. In the color-word Stroop task, the Stroop effect of response time was significantly reduced by 6 and 10 Hz stimulations compared to sham stimulation, and the Stroop effect of accuracy was significantly reduced by 10 Hz stimulation. There were no significant differences in the frequency range-specific (delta, theta, alpha, beta, or gamma) resting EEG power before and after stimulation. (4) Conclusions: HD-tACS at 6 and 10 Hz effectively improved participants’ performance on the color-word Stroop task, demonstrating the importance of the lDLPFC in interference inhibition and supporting a causal relationship between theta and alpha oscillations in interference inhibition.

Introduction: It is clear that mental fatigue can have many negative impacts on individuals, such as impairing cognitive function or affecting performance. The aim of this study was to investigate the role of sound interventions in combating mental fatigue. Method: The subjects were assessed on various scales, a psychomotor vigilance task (PVT) task, and a 3 min resting-state electroencephalogram (EEG), followed by a 20 min mental fatigue–inducing task (Time Load Dual Back, TloadDback), during which subjects in different condition groups listened to either 15 Hz binaural beats, 40 Hz binaural beats, relaxing music, or a 240 Hz pure tone. After the mental fatigue–inducing task, subjects were again assessed on various scales, a PVT task, and a 3 min resting-state EEG. Results: After the fatigue-inducing task, there was no significant difference between the four groups on the scales or the PVT task performance. In TloadDback, the accuracy rate of the 40 Hz binaural beats group and the relaxing music group decreased in the middle stage of the task, while the 15 Hz binaural beats group and the 240 Hz pure tone group remained unchanged in all stages of the task. The EEG results showed that after fatigue inducement, the average path length of the 15 Hz binaural beats group decreased, and local efficiency showed an increasing tendency, indicating enhanced brain network connectivity. Meanwhile, the 240 Hz pure tone group showed enhanced functional connectivity, suggesting a state of mental fatigue in the group. Conclusions: The results of this study show that listening to 15 Hz binaural beats is a proven intervention for mental fatigue that can contribute to maintaining working memory function, enhancing brain topological structure, and alleviating the decline in brain function that occurs in a mentally fatigued state. As such, these results are of great scientific and practical value.

(1) Background: The combined n-back + Go/NoGo paradigm was used to investigate whether audiovisual interactions interfere with or facilitate WM. (2) Methods: College students were randomly assigned to perform the working memory task based on either a single (visual or auditory) or dual (audiovisual) stimulus. Reaction times, accuracy, and WM performance were compared across the two groups to investigate effects of audiovisual interactions. (3) Results: With low cognitive load (2-back), auditory stimuli had no effect on visual working memory, whereas visual stimuli had a small effect on auditory working memory. With high cognitive load (3-back), auditory stimuli interfered (large effect size) with visual WM, and visual stimuli interfered (medium effect size) with auditory WM. (4) Conclusions: Audiovisual effects on WM follow the resource competition theory, and the cognitive load of a visual stimulus is dominated by competition; vision always interferes with audition, and audition conditionally interferes with vision. With increased visual cognitive load, competitive effects of audiovisual interactions were more obvious than those with auditory stimuli. Compared with visual stimuli, audiovisual stimuli showed significant interference only when visual cognitive load was high. With low visual cognitive load, the two stimulus components neither facilitated nor interfered with the other in accordance with a speed–accuracy trade-off.

Background: With the rapid aging of China’s population, the proportion of older adults living alone has increased significantly, bringing their mental health concerns into sharp focus. This study aims to explore the network structure of anxiety and depressive symptoms among older Chinese adults who live alone, thereby identifying central and bridging symptoms to provide scientific evidence for potential intervention targets in prevention and treatment.Methods: A total of 1,952 older Chinese adults, aged 65 and older, living alone, were selected from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) conducted in 2017-2018. We assessed anxiety and depressive symptoms using Generalized Anxiety Disorder Scale (GAD-7) and the Center for Epidemiologic Studies Depression Scale (CES-D). We identified central and bridge symptoms via expected influences (EI) and bridge expected influences (BEI); network stability was evaluated using bootstrap methods.Results: The network structure uncovered four crucial connections between anxiety and depressive symptoms. GAD4 “Trouble relaxing”, GAD2 “Uncontrollable worry”, and CESD3 “Feeling blue/depressed” exhibited the highest EI values within the network. Meanwhile, GAD1 “Nervousness or anxiety” and CESD10 “Sleep disturbances” showed the highest BEI values within their respective communities.Conclusion: This exploratory study is the first to examine the reciprocal relationship between depressive and anxiety symptoms in older Chinese adults living alone. Targeting these central and bridging symptoms may effectively prevent comorbidity and facilitate targeted interventions for those at risk or currently experiencing these symptoms.

This study tested a chain mediation model on whether hopelessness and nostalgia play a mediating role in psychache and suicidal ideation of firefighters. A total of 652 firefighters participated in the survey (male = 94.94%; mean age = 23.71 years, SD = 4.18 years). The firefighters completed the Chinese Revised Psychache Scale (PAS), Beck Hopelessness Scale (BHS), Southampton Nostalgia Scale (SNS), and Columbia-Suicide Severity Rating Scale (C-SSRS). The path analysis results indicated that psychache positively predicted suicidal ideation. Hopelessness plays a significant mediating role between psychache and suicidal ideation further strengthening this relationship. In contrast, nostalgia mediates and weakened the relationship between psychache and suicidal ideation. Hopelessness and nostalgia jointly constructed a chain mediating effect between psychache and suicidal ideation, for higher suicidal ideation with higher hopelessness and lower nostalgia. The findings align with the Three-Step Theory of Suicide, which proposes that suicidal ideation results from the combination of pain and hopelessness and that connectedness is a key protective factor against escalating ideation. Therefore, interventions to reduce suicidal ideation in firefighters should aim to enhance their nostalgia, while reducing sense of hopelessness.