Accurate detection and classification of breast cancer is a critical task in medical imaging due to the complexity of breast tissues. Due to automatic feature extraction ability, deep learning methods have been successfully applied in different areas, especially in the field of medical imaging. In this study, a novel patch-based deep learning method called Pa-DBN-BC is proposed to detect and classify breast cancer on histopathology images using the Deep Belief Network (DBN). Features are extracted through an unsupervised pre-training and supervised fine-tuning phase. The network automatically extracts features from image patches. Logistic regression is used to classify the patches from histopathology images. The features extracted from the patches are fed to the model as input and the model presents the result as a probability matrix as either a positive sample (cancer) or a negative sample (background). The proposed model is trained and tested on the whole slide histopathology image dataset having images from four different data cohorts and achieved an accuracy of 86%. Consequently, the proposed method is better than the traditional ones, as it automatically learns the best possible features and experimental results show that the model outperformed the previously proposed deep learning methods.

Liver segmentation in CT scan images is a significant step toward the development of a quantitative biomarker for computer-aided diagnosis. In this paper, we propose an automatic feature learning algorithm based on deep belief network (DBN) for liver segmentation. The proposed method was based on training by a DBN for unsupervised pretraining and supervised fine tuning. The whole method of pretraining and fine tuning is known as DBN-DNN. In traditional machine learning algorithms, pixel-by-pixel learning is a time-consuming task; therefore, we use blocks as a basic unit for feature learning to identify the liver, which saves memory and computational time. An automatic active contour method is applied to refine the liver in post processing. Experiments on test images show that the proposed algorithm obtained satisfactory results on healthy and pathological liver CT images. Our algorithm achieved 94.80% Dice similarity coefficient on mixed (healthy and pathological) images while 91.83% on pathological liver images, which is better than those of state-of-the-art methods.

CT vertebral segmentation plays an essential role in various clinical applications, such as computer‐assisted surgical interventions, assessment of spinal abnormalities, and vertebral compression fractures. Automatic CT vertebral segmentation is challenging due to the overlapping shadows of thoracoabdominal structures such as the lungs, bony structures such as the ribs, and other issues such as ambiguous object borders, complicated spine architecture, patient variability, and fluctuations in image contrast. Deep learning is an emerging technique for disease diagnosis in the medical field. This study proposes a patch‐based deep learning approach to extract the discriminative features from unlabeled data using a stacked sparse autoencoder (SSAE). 2D slices from a CT volume are divided into overlapping patches fed into the model for training. A random under sampling (RUS)‐module is applied to balance the training data by selecting a subset of the majority class. SSAE uses pixel intensities alone to learn high‐level features to recognize distinctive features from image patches. Each image is subjected to a sliding window operation to express image patches using autoencoder high‐level features, which are then fed into a sigmoid layer to classify whether each patch is a vertebra or not. We validate our approach on three diverse publicly available datasets: VerSe, CSI‐Seg, and the Lumbar CT dataset. Our proposed method outperformed other models after configuration optimization by achieving 89.9% in precision, 90.2% in recall, 98.9% in accuracy, 90.4% in F‐score, 82.6% in intersection over union (IoU), and 90.2% in Dice coefficient (DC). The results of this study demonstrate that our model’s performance consistency using a variety of validation strategies is flexible, fast, and generalizable, making it suited for clinical application.

Public-key infrastructure (PKI) provides the essential foundation for public-key cryptography, and security is often bootstrapped from a PKI. Standardization bodies, organizations, researchers, and experts reached a consensus that deploying Vehicular PKI (VPKI) can ensure the security and privacy requirements of Cooperative Intelligent Transportation Systems (C-ITS). Given the importance of VPKI, researchers and experts have worked to ensure VPKI meets the high security and privacy requirements of C-ITS. This survey focuses on VPKI schemes designed to securely and privately manage and revoke public-key certificates in three parts. The first part presents evaluation metrics that help to compare the existing VPKI proposals systematically. The second part classifies VPKI schemes and provides an overview of each. The third part focuses on observations made using the evaluation metrics through a systematic comparison of VPKI schemes. Finally, suggestions for future VPKI research are presented.

Liver segmentation and recognition from computed tomography (CT) images is a warm topic in image processing which is helpful for doctors and practitioners. Currently, many deep learning methods are used for liver segmentation that takes a long time to train the model which makes this task challenging and limited to larger hardware resources. In this research, we proposed a very lightweight convolutional neural network (CNN) to extract the liver region from CT scan images. The suggested CNN algorithm consists of 3 convolutional and 2 fully connected layers, where softmax is used to discriminate the liver from background. Random Gaussian distribution is used for weight initialization which achieved a distance-preserving-embedding of the information. The proposed network is known as Ga-CNN (Gaussian-weight initialization of CNN). General experiments are performed on three benchmark datasets including MICCAI SLiver’07, 3Dircadb01, and LiTS17. Experimental results show that the proposed method performed well on each benchmark dataset.

Accurate vertebrae segmentation from medical images plays an important role in clinical tasks of surgical planning, diagnosis, kyphosis, scoliosis, degenerative disc disease, spondylolisthesis, and post-operative assessment. Although the structures of bone have high contrast in medical images, vertebrae segmentation is a challenging task due to its complex structure, abnormal spine curves, and unclear boundaries. In recent years, deep learning has been widely applied in the segmentation of vertebrae images. In this paper, towards a robust and automatic segmentation system, we present an overlapping patch-based convNet (OP-convNet) model for automatic vertebrae CT images segmentation. Due to the greater memory and processing costs associated with 3D convolutional neural networks, as well as the risk of over-fitting, we employ overlapping patches in segmentation tasks using 2D convNet. In the proposed vertebrae segmentation method, OP-convNet effectively keeps the local information contained in CT images. We divide CT image slices into equal-sized square overlapping patches and applied the RUS-function on these patches for class balancing to minimize computational requirements. Then, these patches are input into the model along with their corresponding ground truth patches. This method has been evaluated on publicly available CT images from the MICCAI CSI workshop challenge. The results indicate that OP-convNet has precision (PRE) of 90.1%, specificity (SPE) of 99.4%, accuracy (ACC) of 98.8%, F-score of 90.1% in terms of the patch-based classification accuracy, and BF-score of 90.2%, sensitivity (SEN) of 90.3%, Jaccard index (JAC) of 82.3%, dice similarity score (DSC) of 89.9% in terms of the segmentation accuracy that outperform previous methods across all metrics