The implementation of learning has undergone significant changes due to the corona virus (Covid-19) spreading rapidly so that the teaching and learning process at various levels of education is generally carried out online. This urges lecturers to adapt teaching materials to online learning systems, especially subject topics that require laboratory activities. This study aims to develop an e-module for basic chemistry practice courses not only containing material and quizzes but also integrates practical video tutorials in each of its sub-topics. The research method used is research and development (R&D) by applying the ADDIE model. Research respondents were 58 students of the Physics Education FKIP USK wenrolled in basic chemistry practice courses in their first-year study in the 2019-2020. The research data were collected using instruments in the form of students’ responses to the questionnaire on 1) the e-module, and 2) the application of e-modules in basic chemistry laboratory courses. The questionnaires were distributed via Google form to avoid physical contact and comply with health protocols. Prior to distribution, the questionnaire was tested for validity and reliability using the Cronbach's alpha test and analyzed with SPSS version 12 (IDM^TM). The results of the validation show that the mean value of validation is 91.48% for the display, content, grammar, and evaluation system items. Cronbach's alpha test shows a mean alpha value of 0.903. The results of the response questionnaire showed that the average response score was greater than 8.00 for each questionnaire item, while the mean score for the application of the e-module laboratory courses was 8.88. This shows that the e-module for basic chemistry lab work is favorable and suitable for use as teaching material in the online learning process.

Polymeric materials are used for personal protective equipment (PPE), which is mandatory for clinicians to use when handling coronavirus disease 2019 (COVID-19) patients. The development of diagnostic tools and vaccines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is also dependent on polymer technology. This current report aims to provide readers with the trend of polymer research regarding the COVID-19 pandemic, by employing bibliometric analysis. A literature search on the Scopus database (31 January 2022) was carried out using predetermined terms. Using Scopus database features, the publications were filtered based on the year of publication (2020–2022), types of articles (original research and review), and language (English). The metadata were extracted in a CSV (.csv) file, to be later used in VOSviewer software. The data were presented in a table, graph, and network visualization. As many as 512 publications were included, consisting of 66.4% original research articles and 33.6% review articles. Most of the publications were written by authors whose affiliation was in the United States (n = 118, 23%) and covering the Materials Science subject area (n = 142, 27.7%). The Ministry of Education of China was the most productive organization, publishing 11 articles. The National Science Foundation of China was the top funding source, supporting 45 publications. Heinz C. Schröder was the most prolific author, publishing nine articles. Science of the Total Environment was the leading journal publishing the included studies. The trend of polymer technology related to COVID-19 mostly covers PPE and waste-management themes. The use of polymer technology as a delivery system for the anti-SARS-CoV-2 and COVID-19 vaccine is also among the frequently researched areas. We encourage more research in the field of polymer technology be carried out, to overcome the global pandemic.

Essential oils are thought as potential therapies in managing coronavirus disease 2019 (COVID-19). Many researchers have put their efforts to tackle the pandemic by exploring antiviral candidates which consequently changes the research landscape. Herein, we aimed to assess the effect of COVID-19 pandemic toward the landscape of essential oil research. This study employed bibliometric analysis based on the metadata of published literature indexed in the Scopus database. The search was performed on December 15^th, 2022 by using keyword ‘essential oil’ and its synonyms. We grouped the data based on publication year; pre-COVID-19 (2014–2019) and during COVID-19 (2020–2024, some studies have been published earlier). Further, we separated the COVID-19-focused research from COVID-19 (2020–2024) by introducing a new keyword ‘COVID-19’ during the search. All metadata were processed using VoSviewer and Biblioshiny for network visualization analysis. Selections of frequently occurring keywords, clusters of keyword co-occurrence, and the list of most impactful papers were performed by two independent reviewers. Metadata from a total of 35,262 publications were included for bibliometric analysis, comprised of three groups of datasets namely pre-COVID-19 (n = 18,670), COVID-19 (n = 16,592), and COVID-19-focused (n = 281). Five research topics clusters were found from pre-COVID-19 dataset, eight – from COVID-19 dataset, and nine – from COVID-19-focused dataset. COVID-19 cluster containing the keyword ‘antiviral’ emerged in the COVID-19 dataset, whereas none of the previous research topic clusters contained the keyword ‘antiviral’. Antiviral, angiotensin-converting enzyme 2 (ACE2) inhibitory, and anti-inflammation activities were among the top occurring keywords in studies covering both essential oil and COVID-19. Studies on essential oil used for managing COVID-19 were most reported by authors from the United States (documents = 37, citations = 405), Australia (documents = 16, citations = 115) and Italy (documents = 23, citations = 366). A significant increase was found during COVID-19 pandemic for publications covering essential oil themes, but only a small portion was occupied by COVID-19 research. The COVID-19 pandemic does not alter the ongoing progress of essential oil research but rather offers a new spotlight on the antiviral potential of essential oils. Hence, the COVID-19 pandemic has provided an opportunity to investigate deeper the antiviral potential of essential oils.

Serious threat to human health caused by bacterial infection persists as a global concern. It becomes more serious when the burden of multidrug-resistance bacteria is in the increasing trend. To overcome, researches have been conducted to develop antibacterial agents from plant-derived bioactive compounds. This review article focuses on the antibacterial activities of plant extracts from seven Annonaceae members, namely Annona muricata, Annona reticulata, Annona squamosa, Cananga odorata, Annona hypoglauca, Polyalthia longifolia, and Xylopia aethiopica. First, ethnomedical uses of the aforementioned plants are discussed and followed by the screening results of related phytochemicals. Among many secondary metabolites contained in the extracts of Annonaceae spp., anonaine, nornuciferine, and liriodenine are common and bioactive. The extracts were reported to have bacteriostatic and bactericidal properties against a wide spectrum of bacteria, including multidrug-resistant Escherichia coli, Staphylococcus aureus, Bacillus cereus, Enterococcus faecalis, Enterobacter aerogenes, Enterobacter cloacae, Salmonella choleraesuis, Salmonella typhimurium, and Shigella dysenteriae. We conclude that investigation on the extracts from Annonaceae spp. could contribute to the development of antibacterial agents that could be used against multidrug-resistant bacteria.

Increasing trends of environmental pollution and emerging contaminants from anthropogenic activities have urged researchers to develop innovative strategies in wastewater management, including those using the biocatalyst laccase (EC 1.10.3.2). Laccase works effectively against a variety of substrates ranging from phenolic to non-phenolic compounds which only require molecular oxygen to be later reduced to H₂O as the final product. In this study, we performed a bibliometric analysis on the metadata of literature acquired through the Scopus database (24 October 2022) with keyword combination “Laccase” AND “Pollutant” OR “Wastewater”. The included publications were filtered based on year of publication (1978–2022), types of articles (original research articles and review articles) and language (English). The metadata was then exported in a CSV (.csv) file and visualized on VosViewer software. A total of 1865 publications were identified, 90.9% of which were original research articles and the remaining 9.1% were review articles. Most of the authors were from China (n = 416; 22.3%) and India (n = 276; 14.79%). In the case of subject area, ‘Environmental Science’ emerged with the highest published documents (n = 1053; 56.46%). The identified papers mostly cover laccase activity in degrading pollutants, and chitosan, which can be exploited for the immobilization. We encourage more research on laccase-assisted wastewater treatment, especially in terms of collaborations among organizations.