Intravenous thrombolysis is the most commonly used drug therapy for patients with acute ischemic stroke, which is often accompanied by complications of intracerebral hemorrhage transformation (HT). This study proposed to build a reliable model for pretreatment prediction of HT. Specifically, 5400 radiomics features were extracted from 20 regions of interest (ROIs) of multiparametric MRI images of 71 patients. Furthermore, a minimal set of all-relevant features were selected by LASSO from all ROIs and used to build a radiomics model through the random forest (RF). To explore the significance of normal ROIs, we built a model only based on abnormal ROIs. In addition, a model combining clinical factors and radiomics features was further built. Finally, the models were tested on an independent validation cohort. The radiomics model with 14 All-ROIs features achieved pretreatment prediction of HT (AUC = 0.871, accuracy = 0.848), which significantly outperformed the model with only 14 Abnormal-ROIs features (AUC = 0.831, accuracy = 0.818). Besides, combining clinical factors with radiomics features further benefited the prediction performance (AUC = 0.911, accuracy = 0.894). So, we think that the combined model can greatly assist doctors in diagnosis. Furthermore, we find that even if there were no lesions in the normal ROIs, they also provide characteristic information for the prediction of HT.

Weakly Supervised Semantic Segmentation (WSSS) with image-level labels typically uses Class Activation Maps (CAM) to achieve dense predictions. Recently, Vision Transformer (ViT) has provided an alternative to generate localization maps from class-patch attention. However, due to insufficient constraints on modeling such attention, we observe that the Localization Attention Maps (LAM) often struggle with the artifact issue, i.e., patch regions with minimal semantic relevance are falsely activated by class tokens. In this work, we propose MoRe to address this issue and further explore the potential of LAM. Our findings suggest that imposing additional regularization on class-patch attention is necessary. To this end, we first view the attention as a novel directed graph and propose the Graph Category Representation module to implicitly regularize the interaction among class-patch entities. It ensures that class tokens dynamically condense the related patch information and suppress unrelated artifacts at a graph level. Second, motivated by the observation that CAM from classification weights maintains smooth localization of objects, we devise the Localization-informed Regularization module to explicitly regularize the class-patch attention. It directly mines the token relations from CAM and further supervises the consistency between class and patch tokens in a learnable manner. Extensive experiments on PASCAL VOC and MS COCO validate that MoRe effectively addresses the artifact issue and achieves state-of-the-art performance, surpassing recent single-stage and even multi-stage methods.

The accelerated MRI reconstruction process presents a challenging ill-posed inverse problem due to the extensive under-sampling in k-space. Recently, Vision Transformers (ViTs) have become the mainstream for this task, demonstrating substantial performance improvements. However, there are still three significant issues remain unaddressed: (1) ViTs struggle to capture high-frequency components of images, limiting their ability to detect local textures and edge information, thereby impeding MRI restoration; (2) Previous methods calculate multi-head self-attention (MSA) among both related and unrelated tokens in content, introducing noise and significantly increasing computational burden; (3) The naive feed-forward network in ViTs cannot model the multi-scale information that is important for image restoration. In this paper, we propose FPS-Former, a powerful ViT-based framework, to address these issues from the perspectives of frequency modulation, spatial purification, and scale diversification. Specifically, for issue (1), we introduce a frequency modulation attention module to enhance the self-attention map by adaptively re-calibrating the frequency information in a Laplacian pyramid. For issue (2), we customize a spatial purification attention module to capture interactions among closely related tokens, thereby reducing redundant or irrelevant feature representations. For issue (3), we propose an efficient feed-forward network based on a hybrid-scale fusion strategy. Comprehensive experiments conducted on three public datasets show that our FPS-Former outperforms state-of-the-art methods while requiring lower computational costs.

The accelerated MRI reconstruction process presents a challenging ill-posed inverse problem due to the extensive under-sampling in k-space. Recently, Vision Transformers (ViTs) have become the mainstream for this task, demonstrating substantial performance improvements. However, there are still three significant issues remain unaddressed: (1) ViTs struggle to capture high-frequency components of images, limiting their ability to detect local textures and edge information, thereby impeding MRI restoration; (2) Previous methods calculate multi-head self-attention (MSA) among both related and unrelated tokens in content, introducing noise and significantly increasing computational burden; (3) The naive feed-forward network in ViTs cannot model the multi-scale information that is important for image restoration. In this paper, we propose FPS-Former, a powerful ViT-based framework, to address these issues from the perspectives of frequency modulation, spatial purification, and scale diversification. Specifically, for issue (1), we introduce a frequency modulation attention module to enhance the self-attention map by adaptively re-calibrating the frequency information in a Laplacian pyramid. For issue (2), we customize a spatial purification attention module to capture interactions among closely related tokens, thereby reducing redundant or irrelevant feature representations. For issue (3), we propose an efficient feed-forward network based on a hybrid-scale fusion strategy. Comprehensive experiments conducted on three public datasets show that our FPS-Former outperforms state-of-the-art methods while requiring lower computational costs.