Andrea Audisio

Dr. Andrea Audisio

University of Turin, Turin, Piedmont, Italy
orcid

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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19 April 2022 in Injury
Verified
Journal Article
Closed access
Leonardo TanziLeonardo Tanzi
Leonardo Tanzi
AAAndrea Audisio
Andrea Audisio
GCGiansalvo Cirrincione
Giansalvo Cirrincione
AAAlessandro Aprato
Alessandro Aprato
Enrico VezzettiEnrico Vezzetti
Enrico Vezzetti

1 December 2018 in Injury
Verified
Journal Article
Closed access
AAAlessandro Aprato
Alessandro Aprato
AAAndrea Audisio
Andrea Audisio
ASA. Santoro
A. Santoro
EGE. Grosso
E. Grosso
SDS. Devivo
S. Devivo
AMA. Massè
A. Massè

16 September 2024 in Bone Reports
Verified
Journal Article
Open access
GMGiorgia Marullo
Giorgia Marullo
Luca UlrichLuca Ulrich
Luca Ulrich
FAFrancesca Giada Antonaci
Francesca Giada Antonaci
AAAndrea Audisio
Andrea Audisio
AAAlessandro Aprato
Alessandro Aprato
Enrico VezzettiEnrico Vezzetti
Enrico Vezzetti
Femur fractures are a significant worldwide public health concern that affects patients as well as their families because of their high frequency, morbidity, and mortality. When employing computer-aided diagnostic (CAD) technologies, promising results have been shown in the efficiency and accuracy of fracture classification, particularly with the growing use of Deep Learning (DL) approaches. Nevertheless, the complexity is further increased by the need to collect enough input data to train these algorithms and the challenge of interpreting the findings. By improving on the results of the most recent deep learning-based Arbeitsgemeinschaft für Osteosynthesefragen and Orthopaedic Trauma Association (AO/OTA) system classification of femur fractures, this study intends to support physicians in making correct and timely decisions regarding patient care. A state-of-the-art architecture, YOLOv8, was used and refined while paying close attention to the interpretability of the model. Furthermore, data augmentation techniques were involved during preprocessing, increasing the dataset samples through image processing alterations. The fine-tuned YOLOv8 model achieved remarkable results, with 0.9 accuracy, 0.85 precision, 0.85 recall, and 0.85 F1-score, computed by averaging the values among all the individual classes for each metric. This study shows the proposed architecture's effectiveness in enhancing the AO/OTA system's classification of femur fractures, assisting physicians in making prompt and accurate diagnoses.

1 May 2024 in The Bone & Joint Journal
Verified
Journal Article
Closed access
PDF file
AMAlessandro Maria MASSE'
Alessandro Maria MASSE'
MGMatteo Giachino
Matteo Giachino
AAAndrea Audisio
Andrea Audisio
ADAndrea Donis
Andrea Donis
RVRiccardo Giai Via
Riccardo Giai Via
AAAlessandro Aprato
Alessandro Aprato
Aims: Ganz’s studies made it possible to address joint deformities on both the femoral and acetabular side brought about by Perthes’ disease. Femoral head reduction osteotomy (FHRO) was developed to improve joint congruency, along with periacetabular osteotomy (PAO), which may enhance coverage and containment. The purpose of this study is to show the clinical and morphological outcomes of the technique and the use of an implemented planning approach.Methods: From September 2015 to December 2021, 13 FHROs were performed on 11 patients for Perthes’ disease in two centres. Of these, 11 hips had an associated PAO. A specific CT- and MRI-based protocol for virtual simulation of the corrections was developed. Outcomes were assessed with radiological parameters (sphericity index, extrusion index, integrity of the Shenton’s line, lateral centre-edge angle (LCEA), Tönnis angle), and clinical parameters (range of motion, visual analogue scale (VAS) for pain, Merle d'Aubigné-Postel score, modified Harris Hip Score (mHHS), and EuroQol five-dimension five-level health questionnaire (EQ-5D-5L)). Early and late complications were reported.Results: The mean follow-up was 39.7 months (standard deviation (SD) 26.4). The mean age at surgery was 11.4 years (SD 1.6). No major complications were recorded. One patient required a total hip arthroplasty. Mean femoral head sphericity increased from 46.8% (SD 9.34%) to 70.2% (SD 15.44; p < 0.001); mean LCEA from 19.2° (SD 9.03°) to 44° (SD 10.27°; p < 0.001); mean extrusion index from 37.8 (SD 8.70) to 7.5 (SD 9.28; p < 0.001); and mean Tönnis angle from 16.5° (SD 12.35°) to 4.8° (SD 4.05°; p = 0.100). The mean VAS improved from 3.55 (SD 3.05) to 1.22 (1.72; p = 0.06); mean Merle d’Aubigné-Postel score from 14.55 (SD 1.74) to 16 (SD 1.6; p = 0.01); and mean mHHS from 60.6 (SD 18.06) to 81 (SD 6.63; p = 0.021). The EQ-5D-5L also showed significant improvements.Conclusion: FHRO associated with periacetabular procedures is a safe technique that showed improved functional, clinical, and morphological outcomes in Perthes’ disease. The newly introduced simulation and planning algorithm may help to further refine the technique.Cite this article: Bone Joint J 2024;106-B(5 Supple B):40–46.

6 June 2022 in Trauma Care
Verified
Journal Article
Open access
PDF file
AAAlessandro Aprato
Alessandro Aprato
CGCarmelo Giudice
Carmelo Giudice
PBPaolo Bedino
Paolo Bedino
AAAndrea Audisio
Andrea Audisio
AMAlessandro Maria MASSE'
Alessandro Maria MASSE'
Trauma is still the leading cause of death in children. Post mortem studies have shown a high incidence and a high rate of deaths related to pelvic fractures and associated injuries. The pelvic ring in children has characteristics that differentiate it from the adult. The bone tissue is more elastic and is covered with a thick periosteum. Elasticity mainly translates into plastic deformity when it is impacted. Overall, lesions tend to be more stable as the relatively thick periosteum limits bone breakdown. As a result of this elasticity, the intrapelvic organs are more vulnerable and injuries can occur in the absence of fractures. High energy is required to produce a fracture and this energy can be transferred to the pelvic organs. Minimally displaced fractures may be the result of high energy trauma with a significant risk of further intrapelvic and intra-abdominal injury. This leads to a relatively high incidence of pelvic and abdominal organ injuries associated with stable fractures. A complete lesion of the pelvic ring anteriorly or posteriorly or a complex pelvic lesion is a high risk factor for morbidity and mortality. Treatment in the pediatric patient with a pelvic fracture has historically been guided by concepts that have become established in adults. The main parameters in the decision making process are hemodynamic stability and the degree of mechanical instability of the pelvis. The purpose of this review is to report current knowledge on pelvic ring fractures with a particular focus on their management and treatment.

27 December 2024 in Injury
Verified
Journal Article
Closed access
AAAlessandro Aprato
Alessandro Aprato
AAAndrea Audisio
Andrea Audisio
VMVirginia Masoni
Virginia Masoni
CGChiara Guidetti
Chiara Guidetti
SAStefano Artiaco
Stefano Artiaco
AMAlessandro Massè
Alessandro Massè