Lubomír Opletal

Lubomír Opletal

orcid

Research Focus & Metrics

Academic Career Length

35Years (1992-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 May 2008 in Mini-Reviews in Medicinal Chemistry
Verified
Journal Article
Closed access
PDF file
VKVit Koleckar
Vit Koleckar
KKKaterina Kubikova
Katerina Kubikova
ZRZuzana Rehakova
Zuzana Rehakova
KKKamil Kuca
Kamil Kuca
DJDaniel Jun
Daniel Jun
LOLubomír Opletal
Lubomír Opletal
Natural polyphenols are a wide class of secondary plant metabolites and represent an abundant antioxidant component of human diet. An important, but often neglected group of natural polyphenols, are tannins. This review offers a general description of chemistry of both hydrolysable and condensed tannins (proanthocyanidins), the mechanisms of their antioxidation action, like free radical scavenging activity, chelation of transition metals, inhibition of prooxidative enzymes and lipid peroxidation. The mechanisms of action of antibacterial, antiviral, anticarcinogenic, cardiovascular system preventing, and antiinflammatory effects as well as the absorption, metabolic fate and positive in vivo effects of tannins are enclosed.

1 December 2004 in Journal of Chromatography B
Verified
Journal Article
Closed access
LOLubomír Opletal
Lubomír Opletal
HSHelena Sovova
Helena Sovova
MBMilena Bártlová
Milena Bártlová

1 March 2014 in Phytomedicine
Verified
Journal Article
Closed access
RHRadim Havelek
Radim Havelek
MSMartina Seifrtova
Martina Seifrtova
KKKarel Královec
Karel Královec
LBLenka Bruckova
Lenka Bruckova
Lucie CahlikovaLucie Cahlikova
Lucie Cahlikova
ZBZuzana Bilkova
Zuzana Bilkova


19 October 2020 in Molecules
Verified
Journal Article
Open access
PDF file
Lucie CahlikovaLucie Cahlikova
Lucie Cahlikova
KBKateřina Breiterová
Kateřina Breiterová
LOLubomír Opletal
Lubomír Opletal
Lycoris Herbert, family Amaryllidaceae, is a small genus of about 20 species that are native to the warm temperate woodlands of eastern Asia, as in China, Korea, Japan, Taiwan, and the Himalayas. For many years, species of Lycoris have been subjected to extensive phytochemical and pharmacological investigations, resulting in either the isolation or identification of more than 110 Amaryllidaceae alkaloids belonging to different structural types. Amaryllidaceae alkaloids are frequently studied for their interesting biological properties, including antiviral, antibacterial, antitumor, antifungal, antimalarial, analgesic, cytotoxic, and cholinesterase inhibition activities. The present review aims to summarize comprehensively the research that has been reported on the phytochemistry and pharmacology of the genus Lycoris.

18 June 2013 in Chemistry & Biodiversity
Verified
Journal Article
Closed access
PDF file
AKAndrea Kulhánková
Andrea Kulhánková
Lucie CahlikovaLucie Cahlikova
Lucie Cahlikova
ZNZdeněk Novák
Zdeněk Novák
Kateřina MacákováKateřina Macáková
Kateřina Macáková
JKJiří Kuneš
Jiří Kuneš
LOLubomír Opletal
Lubomír Opletal