The spatial distribution of droplet size and velocity affects the deposition and distribution on the target. In order to investigate the influence of different adjuvant and pressures on the spatial distribution of droplet size and velocity in atomization area of different nozzles, air induction flat fan nozzle IDK120-03, multi-range flat fan nozzle LU120-03 and anti-drift flat fan nozzle AD120-03 were selected. Phase Doppler Interferometer (PDI) was used to analyze and compare the distribution of droplet size and velocity in the atomization area of three nozzles when four typical adjuvant Maisi, Maidao, Adsee AB-600 and Surun sprayed at different pressures. The results show that the volume median diameter of droplet size has no obvious change along the vertical direction of the nozzle center and increases with distance in the horizontal direction, the droplet size decreases with increasing pressure at the same position, the adjuvant all increases the droplet size (about 12%, 12%, 10% and 9% for Maisi, Maidao, Surun and Adsee AB-600, respectively), IDK120-03 nozzle droplet size is the largest and LU120-03 nozzle is the smallest in the same position. For droplet velocity distribution, droplet velocity decrease in distance along the vertical and horizontal direction, respectively, the droplet velocity increases with increasing pressure at the same position, compared with water, the droplet velocity increased by about 13%, 9%, 8%, and 4% for Maisi, Maidao, Surun, and Adsee AB-600, respectively, the velocity of AD nozzle is the largest and IDK nozzle is the smallest at the same position. The experiment can provide a basis for the selection of adjuvants and nozzles in pesticide application, and provide a data base for studying the distribution of droplets on the target.