The burgeoning demand for healthcare monitoring has brought field effect transistor (FET) biosensors into the spotlight as a highly efficient detection technology. FET biosensors offer inherent advantages including high sensitivity, rapid response times, operational simplicity, integrability, and label‐free detection. These characteristics render them particularly well‐suited for detecting a diverse array of physiological parameters and biomarkers, thereby furnishing real‐time data crucial for personalized medicine and disease prevention. This review aims to elucidate recent advancements in FET biosensors within the realm of healthcare management encompassing several facets. Initially, this review systematically analyzes the device architecture, sensing mechanisms, and performance evaluation methods of FET biosensors to gain an in‐depth understanding of their operational principles and features. Subsequently, it focuses on the application of FET biosensors for detecting health‐related biomarkers encompassing nucleic acids, proteins, exosomes, viruses, etc. Lastly, the review presents engineered medical sensor prototypes predicated on FET biosensors, such as point‐of‐care testing devices, wearable sensors, and implantable sensors, underscoring their practical utility and potential in health management. In addition, the review addresses critical issues and prospects of using FET biosensors in healthcare monitoring, aiming to provide some references and insights for research and innovation in this field.

For the management of fractured large pores in high-water-bearing reservoirs, the general approach is to use transfer dissection and sealing. Conventional regulators have a limited regulating radius and can only produce blocking in the near-well zone, which is not ideal. Deep dissection technology can expand the radius of action and substantially improve the blocking effect. The existing deep-dissection agent system has problems such as high cost and poor effect, which affect its large-scale application. In this paper, to address these problems, a gel-type dissection modifier cross-linking agent was synthesized and optimized in the laboratory using low-concentration polymer, and the factors affecting the final gel formation effect were experimentally studied. The final polymer concentration was chosen to be 1500 mg/L~3000 mg/L, the poly-crossing ratio was 30:1, the pH was controlled at 7–9, and the temperature was controlled at 30–60 °C; the rubber was formed with good shear resistance and thermal stability, and had good adaptability to the high-mineralization environment. The optimal injection concentration of water-expanded rubber particles for this system was confirmed to be 3000 mg/L. Cryo-electron microscopy was used to observe the morphology of polymer gel formation and the adhesion of nucleated water-expanded particles to the gel, to clarify the mechanism of enhanced retention and sealing of nucleated water-expanded rubber particles by the multiple complex gel system, and finally to verify the sealing performance of the composite sealing system and determine the use effect by indoor simulation experiments with a two-dimensional flat plate model. This study is of great significance for the efficient development of high-water-bearing late reservoirs and further improvement of crude oil recovery.

After long-term polymer flooding, water channeling, and ineffective water circulation occur in oil wells, which seriously affect polymer flooding efficiency and oilfield recovery. The weak gel system has the property of delaying cross-linking. After the weak gel system enters the deep formation, the cross-linking reaction is carried out, which can achieve the purpose of deep regulation and flooding. In this paper, according to the formation characteristics of high temperature, high permeability, and large pores in Y1 block (a block in the Daqing Yushulin Oilfield), the formulation of weak gel system was developed. The optimal formulation was determined by parameters such as gel-forming properties, stability, viscoelasticity, and rheology. Finally, the best formulation for the Y1 block is that containing 0.22% of polyacrylamide (HPAM) and 0.15% of chromium (III) acetate system. The gel-forming time of the formulation is 8 h, and the viscosity can be maintained at 15,000–24,000 mPa·s. Next, this paper studied the factors that affect the gelation of formulations, mainly including dissolved oxygen content, bacterial content, insoluble suspended solids content, and metal ions in the formulation water. The results show that the critical point of the worst effect is the oxygen content close to 1.5 mg/L, and the optimal critical point of oxygen content of the gel system is 7 mg/L. The bacteria in the prepared water degrade the weak gel solution. The more bacteria, the more serious the degradation of the weak gel. A small amount of insoluble suspended solids will greatly increase the viscosity of the weak gel solution, but will accelerate the gel-breaking time. When the content of insoluble suspended solids is high, more than 1000 mg/L, a precipitate will be formed at the bottom of the solution, and the difference in the content of insoluble suspended solids in this interval has little effect on weak gels. The metal ion that mainly affects the gelation effect is Fe²⁺. With the increase of Fe²⁺ mass concentration, the viscosity of weak gel decreases sharply.

The Lamadian oilfield has entered the stage of strong water cut after natural energy development and conventional water flooding development. The use of asphalt binder for profile control can not only adjust the contradiction between layers, expand the swept volume, but also improve the oil displacement efficiency. The field test has achieved certain results. The main oil layer in the Lamadian oilfield has a strong oil layer thickness and serious vertical and plane heterogeneity. After years of water injection development and polymer injection development, most oilfields have entered a period of strong water cut. In the test, it is found that the effect of different well layers is very different, the effect is unstable, and the reason is unclear. Therefore, it is necessary to carry out research on the adaptability and parameter optimization of profile control of asphalt binder through laboratory experiments. In this paper, the asphalt binder provided on site are modified and the dispersion effect of modified asphalt binder is studied, and the concentration of suspending agent is optimized. The artificial cemented core structure and injection method are improved to solve the problem of aggregated asphalt binder on the end face during injection. The displacement profile control experiment was carried out with artificial cores, and the matching relationship between the injected particle size of the asphalt binder and the permeability was determined, and the optimal injection amount was optimized for cores with different permeabilities. The research results show that adding a KCl (potassium chloride solution) solution with a concentration of 2% as a dispersant can exert a better dispersing effect on the asphalt binder. Through the plugging rate experiments of three types of asphalt binder, the profile control effect is determined as the best when the particle size of the asphalt binder is 0.06–0.1 mm. According to the experimental results, the experimental research on the injection concentration and profile control radius of the profile control agent system was carried out. Finally, it was determined that the injection concentration of 3500 mg/L and the profile control radius of 1/3–1/2 of the well spacing were the optimal injection parameters. The field application of a profile control agent provides experimental basis.