When the outbreak of the COVID‐19 delta variant occurred in June 2021, there was a marked increase in Indonesia’s number of self‐isolated patients. The Universitas Indonesia Hospital provided a One‐Stop Service (OSS) to monitor COVID‐19 patients on self‐isolation. This study was conducted to determine the effectiveness of the self‐isolation monitoring performed by hospitals and the factors that determined the outcomes of patients on self‐isolation. This study was conducted using a cross‐sectional method based on secondary data from electronic medical records. Data analysis was performed by determining the relationship of patient risk factors and characteristics with COVID‐19 outcomes. The study found that poorer symptoms, administration of antibiotics, absence of shortness of breath, and normal ALT levels significantly improved the outcome of OSS patients. The study also suggested that during monitoring of patients on COVID‐19 self‐isolation, chest/thorax radiography is necessary. The self‐isolation monitoring program is essential to observe the patient’s condition and evaluate the possibility of deteriorating conditions that could lead to admission decisions in the early or middle stages of the program. This will be beneficial during pandemic emergencies.

Background: The covid-19 pandemic may cause severe clinical manifestations in a vulnerable population, such as pregnant women. Based on Indonesian Obstetrics and Gynecology Association (POGI), the number of maternal deaths due to covid-19 from April 2020 to April 2021 reached 3% and increased to 9% since the delta variant of covid-19 emerged. This research was expected to identify factors that are related to the mortality rate of pregnant women with covid-19. Materials and methods: This was a cross-sectional study using secondary data collected from June 2020 to August 2021. The study was conducted in Universitas Indonesia Hospital, a national covid-19 referral hospital. Patient characteristics, pregnancy profile, comorbidities, laboratory results, chest X-ray examination, treatment options, and the severity of symptoms were evaluated. In addition, bivariate data analysis was carried out using the SPSS device. Results: Out of 114 research subjects, seven patients (6.1%) died, and 107 patients (93.9%) survived. The risk of mortality was significantly (P < 0.05) related to patients' age, duration of hospitalization, gestational age, severity rate of covid-19 , the level of hemoglobin, leukocyte count, platelet count, lymphocytes, the levels of D-dimer, C-reactive protein, transaminase enzymes, urea, creatinine, eGFR, sodium, potassium, and procalcitonin. In addition, significant differences (P < 0.05) related to maternal mortality rate were also shown in the presence of comorbidities (type 2 diabetes, congestive heart failure, coronary artery disease/ acute coronary syndrome, and urinary tract infection), and the use of steroids and tocilizumab. Conclusion: Various factors significantly related to the mortality rate of pregnant women with covid-19. This study may become the basis for a further study with a larger number of subjects, adjustment of assessment and management of covid-19 infected pregnant women, thus hopefully reducing the risk of mortality in pregnant women with covid-19.

In shale hydrocarbon exploration, shale acts as the source rock and reservoir rock. This study aims to evaluate the potentional of shale hydrocarbons based on the laboratory geochemical data and TOC (Total Organic Carbon) modelling. Evaluation of shale hydrocarbons in sthe study field was carried out on two wells, X-1 and X-3 wells with a target in the upper part of Talang Akar formation as a source rock. Geochemical data is needed for evaluating the quality of the source rock by looking at the total organic carbon content, the maturity, and the hydrocarbon produced by the source rock. Analysis of the laboratory geochemical data resulted that the shale of upper Talang Akar formation had enough potential and mature organic material and also will generate the hydrocarbon in oil form. One of the main parameters for the success of shale hydrocarbons exploration is to know the amount of organic material of the source rock. TOC obtained from laboratory geochemical data is discrete data. Therefore, TOC modelling is carried out to obtain prediction of continuous TOC in upper Talang Akar formation in both wells. This prediction uses three different methods, those are Passey, multiple linear regression, and neural network. Based on those three methods, neural network produces the best data. The correlation obtained from X-1 well and X-3 well using neural network method are 0.96 and 0.84 respectively.

Objective: This study aimed to evaluate the efficacy and acceptability of thermal ablation (TA) as a treatment modality in patients with positive Documented Visual Inspection with Acetic Acid (Do-VIA) results, in a low-resource clinical setting. Methods: A retrospective cohort study was conducted at the VIA clinic of Cipto Mangunkusumo National Referral Hospital (RSCM), Jakarta, Indonesia, from January to July 2024. Patients with positive VIA-DoVIA results were treated with thermal ablation therapy (also known as cold coagulation) and followed up for three months to assess clinical outcomes and acceptability. Results: Out of 99 patients who underwent VIA screening, 47 tested positive. Of these, 35 received thermal ablation therapy. Three months post-treatment, 25 patients tested negative on VIA, while only 3 patients remained VIA-positive. Patient-reported side effects included clear vaginal discharge (52%), vaginal discharge with blood spots (3%), itchy discharge (38%), and short-term vaginal spotting (7%). No severe adverse events were reported. Conclusion: Thermal ablation therapy appears to be an effective and well-tolerated alternative to cryotherapy for the treatment of cervical precancerous lesions. It demonstrates good efficacy, minimal side effects, and high acceptability among healthcare providers in low-resource settings.