Epilepsy is a brain disorder disease that affects people’s quality of life. Electroencephalography (EEG) signals are used to diagnose epileptic seizures. This paper provides a computer-aided diagnosis system (CADS) for the automatic diagnosis of epileptic seizures in EEG signals. The proposed method consists of three steps, including preprocessing, feature extraction, and classification. In order to perform the simulations, the Bonn and Freiburg datasets are used. Firstly, we used a band-pass filter with 0.5–40 Hz cut-off frequency for removal artifacts of the EEG datasets. Tunable-Q Wavelet Transform (TQWT) is used for EEG signal decomposition. In the second step, various linear and nonlinear features are extracted from TQWT sub-bands. In this step, various statistical, frequency, and nonlinear features are extracted from the sub-bands. The nonlinear features used are based on fractal dimensions (FDs) and entropy theories. In the classification step, different approaches based on conventional machine learning (ML) and deep learning (DL) are discussed. In this step, a CNN–RNN-based DL method with the number of layers proposed is applied. The extracted features have been fed to the input of the proposed CNN–RNN model, and satisfactory results have been reported. In the classification step, the K-fold cross-validation with k = 10 is employed to demonstrate the effectiveness of the proposed CNN–RNN classification procedure. The results revealed that the proposed CNN–RNN method for Bonn and Freiburg datasets achieved an accuracy of 99.71% and 99.13%, respectively.

In recent years, improved deep learning techniques have been applied to biomedical image processing for the classification and segmentation of different tumors based on magnetic resonance imaging (MRI) and histopathological imaging (H&E) clinical information. Deep Convolutional Neural Networks (DCNNs) architectures include tens to hundreds of processing layers that can extract multiple levels of features in image-based data, which would be otherwise very difficult and time-consuming to be recognized and extracted by experts for classification of tumors into different tumor types, as well as segmentation of tumor images. This article summarizes the latest studies of deep learning techniques applied to three different kinds of brain cancer medical images (histology, magnetic resonance, and computed tomography) and highlights current challenges in the field for the broader applicability of DCNN in personalized brain cancer care by focusing on two main applications of DCNNs: classification and segmentation of brain cancer tumors images.

This paper proposes a new method for epileptic seizure detection in electroencephalography (EEG) signals using nonlinear features based on fractal dimension (FD) and a deep learning (DL) model. Firstly, Bonn and Freiburg datasets were used to perform experiments. The Bonn dataset consists of binary and multi-class classification problems, and the Freiburg dataset consists of two-class EEG classification problems. In the preprocessing step, all datasets were prepossessed using a Butterworth band pass filter with 0.5–60 Hz cut-off frequency. Then, the EEG signals of the datasets were segmented into different time windows. In this section, dual-tree complex wavelet transform (DT-CWT) was used to decompose the EEG signals into the different sub-bands. In the following section, in order to feature extraction, various FD techniques were used, including Higuchi (HFD), Katz (KFD), Petrosian (PFD), Hurst exponent (HE), detrended fluctuation analysis (DFA), Sevcik, box counting (BC), multiresolution box-counting (MBC), Margaos-Sun (MSFD), multifractal DFA (MF-DFA), and recurrence quantification analysis (RQA). In the next step, the minimum redundancy maximum relevance (mRMR) technique was used for feature selection. Finally, the k-nearest neighbors (KNN), support vector machine (SVM), and convolutional autoencoder (CNN-AE) were used for the classification step. In the classification step, the K-fold cross-validation with k = 10 was employed to demonstrate the effectiveness of the classifier methods. The experiment results show that the proposed CNN-AE method achieved an accuracy of 99.736% and 99.176% for the Bonn and Freiburg datasets, respectively.