Carcinoma of the lungs is among the most menacing forms of malignancy and has a poor prognosis, with a low overall survival rate due to delayed detection and ineffectiveness of conventional therapy. Therefore, drug delivery strategies that may overcome undesired damage to healthy cells, boost therapeutic efficacy, and act as imaging tools are currently gaining much attention. Advances in material science have resulted in unique nanoscale-based theranostic agents, which provide renewed hope for patients suffering from lung cancer. Nanotechnology has vastly modified and upgraded the existing techniques, focusing primarily on increasing bioavailability and stability of anti-cancer drugs. Nanocarrier-based imaging systems as theranostic tools in the treatment of lung carcinoma have proven to possess considerable benefits, such as early detection and targeted therapeutic delivery for effectively treating lung cancer. Several variants of nano-drug delivery agents have been successfully studied for therapeutic applications, such as liposomes, dendrimers, polymeric nanoparticles, nanoemulsions, carbon nanotubes, gold nanoparticles, magnetic nanoparticles, solid lipid nanoparticles, hydrogels, and micelles. In this Review, we present a comprehensive outline on the various types of overexpressed receptors in lung cancer, as well as the various targeting approaches of nanoparticles.
Bioinspired metallic nanoparticles (BMN) have revolutionized the biomedical domain and are still developing rapidly. Hence, this review on BMN elaborates the properties, biosynthesis, biomedical applications, and its role in combating the SARS-CoV-2.
This study reports plant mediated-copper oxide nanoparticles synthesis from Annona squamosa and their real-life application in agricultural domain for label-free detection of H2O2 and its antibacterial efficiency for combating rice crop pathogen.
The exponential surge in energy demand, driven by technological progress and evolving lifestyles, has precipitated a critical juncture. Energy sourcing now spans the spectrum from conventional to renewable alternatives. The limitations of conventional sources, entwined with their contributions to ecological degradation, deforestation, and the amplification of global warming and climate change, have come to the forefront. In response, renewable energy sources have surged into prominence, capturing both industrial and scientific attention. This comprehensive review navigates through the labyrinth of technological hurdles, breakthroughs, and heightened efficiencies that characterize diverse solar cell (SC) paradigms. Importantly, this exploration encompasses SC materials grouped under II–VI, III–V, and perovskite categories. While these materials bear utility, their intrinsic carcinogenic nature raises alarms regarding potential ecological and health impacts. The imperative to cultivate ecologically mindful alternatives reverberates as a persistent motif, underscored by a dedicated focus on the maturation of environmentally friendly carbon-based SCs. In this study, a meticulous comparative investigation of pivotal performance indicators such as Voc, Isc, fill-factor, and efficiency is meticulously conducted. This assessment spans an expansive array of materials and substrates utilized within the realm of SCs. In a broader context, the ultimate aspiration of this paper is to untie the intricate interaction of factors that govern the trajectory of solar cell performance. By doing so, it serves as an illuminating guidepost, steering the course of inquiry and advancement in the domain of sustainable energy technologies.
This work deals with the synthesis of bioinspired triangular ZnO nanoclusters (bT-ZnO NCs) from Argyreia nervosa nascent leaf extract for their effective antibacterial activity and further utilization as a platform for the electrocatalytic determination of ascorbic acid (AA; vitamin C) for applications in the agricultural domain. The structural, optical, and morphological characteristics of the synthesized bT-ZnO NCs were analyzed by UV-vis, FT-IR, XRD, AFM, SEM, TEM, HR-TEM, and EDX techniques. After this, bT-ZnO NCs were electrophoretically deposited onto an indium-tin-oxide (ITO) glass substrate and assessed for the electro-oxidation of AA by cyclic voltammetry (CV), and from this it was proven that bT-ZnO NCs had a very high electrochemical sensitivity of 29.88 μA cm−2 toward AA and a low limit of detection of 0.5321 mM under the optimized experimental conditions. Thus, it provides a potential sensing platform for electrochemical studies to detect AA. Moreover, bT-ZnO NCs were preliminarily investigated for their antibacterial activity, and the obtained results showed that the bT-ZnO NCs have potency as an antibacterial agent.