Purpose: This study aims at identifying the contribution of Industry 4.0 (I4.0) integration into supply chains (SCs) to the enhancement of SC resilience.Design/methodology/approach: A scoping review was conducted so that the relevant literature on SC resilience, and I4.0 integrated into SC management was examined.Findings: The authors summarize the main findings from existing research and propose three research directions: (1) empirical validation of the contribution of I4.0 ICTs to SC resilience; (2) explore the role of processing-actuation technologies in enhancing restorative capacity; and (3) integration between I4.0 ICTs and omni-channel strategy as a means to resilience development at consumer and retail levels. The literature on the design of resilient smart SCs is far outnumbered by works reporting applications of I4.0 ICTs at different SC tier levels. However, the authors’ scoping review organizes the information available on these themes, setting the ground for the development of new theoretical propositions.Originality/value: The integration of digital technologies from I4.0 can fundamentally change the SC management, acting as enablers of a more effective response to disruptions. However, the digital transformation of SCs is still incipient, and literature is particularly sparse when considering the contribution of I4.0 to the resilience of SCs.