Li Li

Dr. Li Li

orcid

Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 January 2014 in BMC Chemistry
Verified
Journal Article
Open access
PDF file
DTDongyan Tang
Dongyan Tang
YDYinmao Dong
Yinmao Dong
HRHankun Ren
Hankun Ren
LLLi Li
Li Li
CHCongfen He
Congfen He
The seeds and sprouts of mung bean (Vigna radiata), a common food, contain abundant nutrients with biological activities. This review provides insight into the nutritional value of mung beans and its sprouts, discussing chemical constituents that have been isolated in the past few decades, such as flavonoids, phenolic acids, organic acids, amino acids, carbohydrates, and lipids. Moreover, we also summarize dynamic changes in metabolites during the sprouting process and related biological activities, including antioxidant, antimicrobial, anti-inflammatory, antidiabetic, antihypertensive, lipid metabolism accommodation, antihypertensive, and antitumor effects, etc., with the goal of providing scientific evidence for better application of this commonly used food as a medicine.

11 July 2017 in BMC Chemistry
Verified
Journal Article
Open access
PDF file
WZWenyi Zhu
Wenyi Zhu
YDYijie Du
Yijie Du
HMHong MENG
Hong MENG
YDYinmao Dong
Yinmao Dong
LLLi Li
Li Li
Tribulus terrestris L. (TT) is an annual plant of the family Zygophyllaceae that has been used for generations to energize, vitalize, and improve sexual function and physical performance in men. The fruits and roots of TT have been used as a folk medicine for thousands of years in China, India, Sudan, and Pakistan. Numerous bioactive phytochemicals, such as saponins and flavonoids, have been isolated and identified from TT that are responsible alone or in combination for various pharmacological activities. This review provides a comprehensive overview of the traditional applications, phytochemistry, pharmacology and overuse of TT and provides evidence for better medicinal usage of TT.

19 June 2018 in Chinese Medicine
Verified
Journal Article
Open access
HLHai-bo LIU
Hai-bo LIU
LLLi Li
Li Li
LXLijia Xu
Lijia Xu
HMHong MENG
Hong MENG
YDYin-Mao Dong
Yin-Mao Dong
PXPeigen Xiao
Peigen Xiao
In recent years, studies of traditional medicinal plants have gradually increased worldwide because the natural sources and variety of such plants allow them to complement modern pharmacological approaches. As computer technology has developed, in silico approaches such as virtual screening and network analysis have been widely utilized in efforts to elucidate the pharmacological basis of the functions of traditional medicinal plants. In the process of new drug discovery, the application of virtual screening and network pharmacology can enrich active compounds among the candidates and adequately indicate the mechanism of action of medicinal plants, reducing the cost and increasing the efficiency of the whole procedure. In this review, we first provide a detailed research routine for examining traditional medicinal plants by in silico techniques and elaborate on their theoretical principles. We also survey common databases, software programs and website tools that can be used for virtual screening and pharmacological network construction. Furthermore, we conclude with a simple example that illustrates the whole methodology, and we present perspectives on the development and application of this in silico methodology to reveal the pharmacological basis of the effects of traditional medicinal plants.

16 November 2018 in Chinese Medicine
Verified
Journal Article
Open access
PDF file
LLLian Ying Liao
Lian Ying Liao
YHyifan HE
yifan HE
LLLi Li
Li Li
HMHong MENG
Hong MENG
YDYin-Mao Dong
Yin-Mao Dong
HLHai-bo LIU
Hai-bo LIU
Modern studies have shown that adaptogens can non-specifically enhance the resistance of human body under a wide range of external stress conditions with a multi-targeted and multi-channel network-like manner, especially by affect the immune-neuro-endocrine system and the hypothalamic–pituitary–adrenal axis. This review article draws the attention to the relationships of adaptogens, tonics from traditional Chinese medicine (TCM) and ginseng-like herbs worldwide, which all have similar plant sources and clinical applications. To clarify the sources and pharmacological mechanisms of these plant-originated adaptogens, which will provide useful information for the utilization of adaptogens to improve the human health. Meanwhile, the TCMs and the world-wide ginseng-like herbs from each region’s ethnopharmacology will be beneficial modernization and globalization.

29 November 2019 in Biomedical Dermatology
Verified
Journal Article
Open access
PDF file
YYYunli Yang
Yunli Yang
HZHuina Zhang
Huina Zhang
JZJinhui Zuo
Jinhui Zuo
XGXiaoyan Gong
Xiaoyan Gong
FYFan Yi
Fan Yi
LLLi Li
Li Li
Background: Ganoderma lucidum, a double-walled basidiospore produced by porous basidiomycete fungi, has been used as a traditional medicine for thousands of years. It is considered a valuable Chinese medicine for strengthening body resistance, invigorating the spleen, and replenishing Qi. G. lucidum contains a variety of active ingredients, such as polysaccharides, triterpenoids, nucleosides, sterols, alkaloids, polypeptides, fatty acids, steroids, and inorganic elements, and has anticancer, anti-inflammatory, hepatoprotection, hypoglycemic, anti-melanogenesis, anti-aging, and skin barrier-repairing activity. Conclusions: The review summarizes the traditional usages, distribution, active constituents, structure, and biological effects of G. lucidum, with an aim to offer directions for further research and better usage of G. lucidum as a medicinal raw material.

18 July 2013 in BMC Chemistry
Verified
Journal Article
Open access
PDF file
YDYinmao Dong
Yinmao Dong
DTDongyan Tang
Dongyan Tang
ZNZhang Na
Zhang Na
YLYue Li
Yue Li
CZChunhong Zhang
Chunhong Zhang
MLMinhui Li
Minhui Li
In China, several species (Hedysarum polybotrys Hand.-Mazz., Hedysarum limprichtii Hlbr., Hedysarum vicioider Turcz. var. Taipeicum Hand.-Mazz. Liu, Hedysarum smithianum, et al.) of genus Hedysarum have a long history of use in traditional Chinese medicine (TCM). In TCM, these plants are used to increase the energy of the body. To date, 155 compounds, including flavonoids, triterpenes, coumarins, lignanoids, nitrogen compounds, sterols, carbohydrates, fatty compounds, and benzofuran, have been isolated from plants of the genus Hedysarum. Various chemical constituents contribute to the antioxidant, anti-tumor, anti-aging, anti-diabetic, and anti-hypertensive properties of these plants. Hedysarum species are used to treat infestation with gastrointestinal nematodes and may support the immune system and peripheral nervous system. In the present review, we summarize the research on the phytochemistry and pharmacology of Hedysarum species, which will be useful for better utilization of these important species in TCM.