Maria Rosario Morales Lozano

Dr. Maria Rosario Morales Lozano


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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3 August 2022 in Journal of Clinical Medicine
Verified
Journal Article
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ACAlvaro Gomez Carrion
Alvaro Gomez Carrion
MAM Angeles Atin Arratibel
M Angeles Atin Arratibel
MLMaria Rosario Morales Lozano
Maria Rosario Morales Lozano
CRCarmen Martínez Rincón
Carmen Martínez Rincón
CMCarlos Martínez-Sebastián
Carlos Martínez-Sebastián
Ruben Sanchez-GomezRuben Sanchez-Gomez
Ruben Sanchez-Gomez
The lateral wedge insole (LWI) is a typical orthopedic treatment for medial knee osteoarthritis pain, chronic ankle instability, and peroneal tendon disorders. It is still unknown what the effects are in the most important joints of the foot when using LWIs as a treatment for knee and ankle pathologies. Objectives: The aim of this study was to determine the influence of LWIs on the position of the midfoot and rearfoot joints by measuring the changes using a tracking device. Methods: The study was carried out with a total of 69 subjects. Movement measurements for the midfoot were made on the navicular bone, and for the rearfoot on the calcaneus bone. The Polhemus system was used, with two motion sensors fixed to each bone. Subjects were compared by having them use LWIs versus being barefoot. Results: There were statistically significant differences in the varus movement when wearing a 4 mm LWI (1.23 ± 2.08°, p < 0.001) versus the barefoot condition (0.35 ± 0.95°), and in the plantarflexion movement when wearing a 4 mm LWI (3.02 ± 4.58°, p < 0.001) versus the barefoot condition (0.68 ± 1.34°), in the midfoot. There were also statistically significant differences in the valgus movement when wearing a 7 mm LWI (1.74 ± 2.61°, p < 0.001) versus the barefoot condition (0.40 ± 0.90°), and in the plantar flexion movement when wearing a 4 mm LWI (2.88 ± 4.31°, p < 0.001) versus the barefoot condition (0.35 ± 0.90°), in the rearfoot. Conclusions: In the navicular bone, a varus, an abduction, and plantar flexion movements were generated. In the calcaneus, a valgus, an adduction, and plantar flexion movements were generated with the use of LWIs.

Verified
Journal Article
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RFRebeca Bueno Fermoso
Rebeca Bueno Fermoso
MLMaria Rosario Morales Lozano
Maria Rosario Morales Lozano
MCMarta Nieto Cordero
Marta Nieto Cordero
CRCarmen Martínez Rincón
Carmen Martínez Rincón
PFPablo García Fernández
Pablo García Fernández
MFMaria luz Gonzalez Fernandez
Maria luz Gonzalez Fernandez
Objectives: Metatarsalgia continues to be a problem in patients with rheumatoid arthritis (RA) in remission (remRA), as well as in the non-rheumatic population, with a mechanical origin. Identify and compare clinical, morphological, disability, synovitis (ultrasound), and radiological osteoarticular damage characteristics in two groups of patients with lesser-ray metar-tarsalgia, with remRA, and without RA. Methods: Cross-sectional study with 84 patients with remRA (mRA) and 60 patients without RA (nmRA). The study evaluated five clinical variables (pain, Foot Function Index (FFI), joint mobility, digital deformities, and foot type), a radiological variable (osteoarticular damage), and an ultrasound variable (metatarsal synovitis). The data were analysed using descriptive and correlational techniques. Results: There were no significant differences in sex, age, body mass index (BMI), or degree of pain. Both groups showed a high prevalence of limited joint mobility for the ankle and first metatarsal phalanx (DF1st MTPJ) and digital deformities, with no statistically significant differences. Similarly, there were no differences in lesser-ray synovitis. On the other hand, there were differences in mRA with greater disability and activity limitation (FFI), LDD (lesser-ray digital deformities) stiffness, first-ray deformities, radiological damage, synovitis in 1st MTPJ, and positive Doppler (five patients). Conclusions: Metatarsalgia presents similarities in both populations. Biomechanical factors may influence the symptoms and presence of synovitis in patients with RA in remission. Other characteristics are more frequent in mRA, which could be related to the disease; thus, future research should include both biomechanical and ultrasound exploration of the foot in the valuation of patients in remission.

6 July 2021 in Clinical Rheumatology
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PPPilar Macarrón Pérez
Pilar Macarrón Pérez
MLMaria Rosario Morales Lozano
Maria Rosario Morales Lozano
CFCristina Vadillo Font
Cristina Vadillo Font
LALidia Abásolo Alcázar
Lidia Abásolo Alcázar
CRCarmen Martínez Rincón
Carmen Martínez Rincón
MGMaría Luz González-Fernández
María Luz González-Fernández
Introduction: Patients with rheumatoid arthritis frequently consult for pain resulting from involvement of the tendons of the foot. This pain negatively affects foot biomechanics and quality of life. The most widely used treatment option for this condition is ultrasound-guided steroid injection, while other treatments were recommended such as heel pad, splints, and footwear. Objective: To evaluate a joint intervention (rheumatology and podiatry) comprising an orthotic-podiatric treatment and infiltrations. We evaluated the response using ultrasound monitoring, a pain scale, functional tests, and assessment of patient satisfaction. Methods: We performed a non-controlled blinded prospective interventional study of 96 patients with foot pain and selected those with ultrasound-confirmed tendon involvement. Patients enrolled started intervention treatment and were followed for 6 months. The outcome of the intervention was compared with the patient’s baseline status. The pre-post differences in the secondary variables (pain, disability) were analyzed using the t test and contingency tables or the Mann–Whitney test. Results: Using our protocol, we recorded a rapid and significant reduction in the intensity of pain, in the foot function index, and in the ultrasound parameters (grayscale and Doppler). Structural damage to the tendon improved more slowly, with significant outcomes only at the last visit with respect to baseline. Abnormal foot support was detected in 50% of patients, and 79.5% were using inappropriate footwear. Conclusions: Our multidisciplinary therapeutic protocol enabled a very significant improvement in tendon involvement. It was well-tolerated, with a high degree of satisfaction, and was easily evaluated using ultrasound. No changes in background medication were necessary. Key Points• Multidisciplinary evaluation of patients with RA is advisable because it improves the treatment management in cases of inflammatory activity and structural abnormalities of the foot.• Comprising orthopedic-podiatric treatment (heel, splints, and suitable footwear) and infiltrations, in terms of clinical, ultrasound, and functional recovery of the foot tendons.• The therapy protocol we propose led to a significant improvement in pain relief and functional recovery.

21 January 2022 in Sensors
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Journal Article
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ACAlvaro Gomez Carrion
Alvaro Gomez Carrion
MAM Angeles Atin Arratibel
M Angeles Atin Arratibel
MLMaria Rosario Morales Lozano
Maria Rosario Morales Lozano
CMCarlos Martínez-Sebastián
Carlos Martínez-Sebastián
BDBlanca De-la-Cruz-Torres
Blanca De-la-Cruz-Torres
Ruben Sanchez-GomezRuben Sanchez-Gomez
Ruben Sanchez-Gomez
Background: The rearfoot varus wedge (RVW) is a common treatment for foot pain and valgus deformity. There is research on its effects in the calcaneus, but there is little research on the navicular. More research is needed with the use of RVW due to the relationship that exists between the position of the navicular and the risk of suffering an injury. Objectives: this study sought to understand how RVW can influence the kinematics of the navicular bone, measuring their movement with the 6 SpaceFastrak system. Methods: a total of 60 subjects participated in the study. Two sensors were used to measure the movement of the calcaneus and navicular using RVWs as compared in the barefoot position in a static way. Results: there were statistically significant differences, the use of RVWs caused changes in the navicular bone, with subjects reaching the maximum varus movement with the use of RVW 7 mm of 1.35 ± 2.41° (p < 0.001), the maximum plantar movement flexion with the use of RVW 10 mm of 3.93 ± 4.44° (p < 0.001). Conclusions: when RVWs were placed under the calcaneus bone, the navicular bone response was in varus movement too; thus, the use of rearfoot varus wedge can influence the movement of the navicular bone.

20 August 2025 in Biomedicines
Verified
Journal Article
Open access
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RFRebeca Bueno Fermoso
Rebeca Bueno Fermoso
MLMaria Rosario Morales Lozano
Maria Rosario Morales Lozano
CRCarmen Martínez Rincón
Carmen Martínez Rincón
PFPablo García Fernández
Pablo García Fernández
JGJuan Miguel lopez Gonzalez
Juan Miguel lopez Gonzalez
MFMaria luz Gonzalez Fernandez
Maria luz Gonzalez Fernandez
Background: Foot pain often persists in patients with rheumatoid arthritis (RA), even during clinical remission. However, its causes are not fully understood. Identifying factors specifically associated with metatarsal pain, rather than generalized foot pain, may improve targeted management strategies. Objectives: The aim of this study was to compare the clinical, biomechanical, and radiological characteristics of RA patients in remission with isolated metatarsal pain versus those with pain in other foot regions, and to identify independent predictors of metatarsal pain. Methods: This cross-sectional study included 118 RA patients in remission, classified into two groups: isolated metatarsal pain (n = 61) and pain in other foot regions (n = 57). Clinical variables (demographics, disease duration, treatment, comorbidities), biomechanical measures (ankle, first metatarsophalangeal and subtalar joint mobility, hallux valgus severity, foot type), radiographic findings (erosions, subluxations), and ultrasound-detected synovitis in the 2nd–5th metatarsophalangeal (MTP) joints were recorded. Independent predictors were identified using binary logistic regression. Results: Patients with metatarsal pain had higher rates of severe hallux valgus, MTP synovitis, and dislocations ≥ 50%. Independent predictors were hallux valgus (OR = 5.428, 95% CI: 1.528–19.287, p = 0.009), MTP synovitis (OR = 2.093, 95% CI: 1.337–3.275, p = 0.001), and MTP dislocations (OR = 2.092, 95% CI: 1.275–3.432, p = 0.003). Conclusions: Persistent metatarsal pain in RA remission is associated with a distinct structural and biomechanical profile. Comparing foot pain by location may help identify clinically relevant patterns and support more individualized assessment and treatment strategies. Due to the cross-sectional design, causality cannot be established.

12 February 2026 in Journal of Foot and Ankle Research
Verified
Journal Article
Open access
RFRebeca Bueno Fermoso
Rebeca Bueno Fermoso
MLMaria Rosario Morales Lozano
Maria Rosario Morales Lozano
CRCarmen Martínez Rincón
Carmen Martínez Rincón
PFPablo García Fernández
Pablo García Fernández
JGJuan Miguel lopez Gonzalez
Juan Miguel lopez Gonzalez
MFMaria luz Gonzalez Fernandez
Maria luz Gonzalez Fernandez
Background: Patients with rheumatoid arthritis (RA) may continue to experience foot‐related disability despite clinical remission. Foot involvement is associated with self‐reported disability and objective gait alterations. Foot involvement is heterogeneous; studying patients with localised forefoot pain may help clarify which structural and inflammatory factors are associated with functional impairment. Objectives: To identify clinical, structural and imaging factors associated with disability and gait performance in patients with RA in clinical remission with metatarsal‐region forefoot pain. Methods: Cross‐sectional study of 81 patients with RA in remission with metatarsal‐region forefoot pain. Outcomes were Foot Function Index disability and activity limitation (FFI‐D and FFI‐AL), gait velocity (GV) and double‐support time (DS). Associations were examined using Spearman correlations, age‐ and BMI‐adjusted individual linear regression, parsimonious multivariable linear regression and exploratory cluster analysis. Results: Mean (SD) FFI‐D and FFI‐AL were 29.8 (29.4) and 29.1 (27.7); gait velocity (GV) was 0.90 (0.34) m/s and double‐support time (DS) was 22.9 (8.2)% of the gait cycle. In bivariate and age/BMI‐adjusted analyses, graded structural measures showed more consistent associations with disability and gait outcomes than dichotomous/count variables. In parsimonious models, disability (FFI‐D/FFI‐AL) was independently associated with pain intensity (VAS) and first metatarsophalangeal joint stiffness/limited dorsiflexion (1stMTP), whereas gait performance was mainly associated with age/BMI, greater graded forefoot structural severity and 1stMTP. Cluster analysis identified a higher grey‐scale synovitis (GS)/lower structural‐burden group and a lower GS/higher structural‐burden group, with worse function and slower gait in the latter. Conclusions: In RA remission with metatarsal‐region forefoot pain, perceived disability is mainly associated with pain and forefoot stiffness, whereas gait performance is more closely related to age/BMI and graded forefoot structural severity. These findings support severity‐based region‐specific structural assessment alongside pain evaluation in clinical follow‐up, to avoid underestimating the independent contribution of structural damage to function and gait.