The first months of 2020 saw the coronavirus pandemic explode. Moving from China, it arrived in Europe and hit Italy. The place where the debate around it exploded was the media ecosystem. In a short time, it was an explosion of tweets related to the hashtag #coronavirus on Twitter. With the aim of reconstructing the meanings of the hashtag and the content, in terms of sentiment and opinions, of the reactions of the Italians, we collected in a large size corpus, the hundred thousand Italian tweets containing the #coronavirus produced during the media hype period from the Twitter repository (February 24th - 28th, 2020). Media hype period was discovered by digging in the online articles of ‘la Repubblica', based on the presence of the words: coronavirus and Italy. The media hype is February 26th. The corpus underwent Emotional Text Mining (ETM), an unsupervised methodology, which allows social profiling based on communication. The study of the word chosen to talk about a topic and their co-occurrence allows the understanding of people’s symbolizations, representations, and sentiment, about the coronavirus. In a retrospective logic, this mechanism allows us to reconstruct the sensemaking and nuances of meaning attributed by users to the coronavirus hashtag.

Purpose: This work reports the extension of a semiempirical method based on the correlation ratios to convert electronic portal imaging devices transit signals into in vivo doses for the step-and-shoot intensity-modulated radiotherapy Siemens beams. The dose reconstructed at the isocenter point D_iso, compared to the planned dose, D_iso,TPS, and a γ-analysis between 2-dimensional electronic portal imaging device images obtained day to day, seems to supply a practical method to verify the beam delivery reproducibility. Method: The electronic portal imaging device images were obtained by the superposition of many segment fields, and the algorithm for the D_iso reconstruction for intensity-modulated radiotherapy step and shoot was formulated using a set of simulated intensity-modulated radiotherapy beams. Moreover, the in vivo dose-dedicated software was integrated with the record and verify system of the centers. Results: Three radiotherapy centers applied the in vivo dose procedure at 30 clinical intensity-modulated radiotherapy treatments, each one obtained with 5 or 7 beams, and planned for patients undergoing radiotherapy for prostatic tumors. Each treatment beam was checked 5 times, obtaining 900 tests of the ratios R = D_iso/D_iso,TPS. The average R value was equal to 1.002 ± 0.056 (2 standard deviation), while the mean R value for each patient was well within 5%, once the causes of errors were removed. The γ-analysis of the electronic portal imaging device images, with 3% 3 mm acceptance criteria, showed 90% of the tests with P_{γ < 1} ≥ 95% and γ_mean ≤ 0.5. The off-tolerance tests were found due to incorrect setup or presence of morphological changes. This preliminary experience shows the great utility of obtaining the in vivo dose results in quasi real time and close to the linac, where the radiotherapy staff may immediately spot possible causes of errors. The in vivo dose procedure presented here is one of the objectives of a project, for the development of practical in vivo dose procedures, financially supported by the Istituto Nazionale di Fisica Nucleare.