Graduated in Biological Sciences from the University of São Paulo, she holds a Master's and PhD in Biology/Genetics from the University of São Paulo. She is currently a senior professor at the University of São Paulo, in the Department of Cellular and Developmental Biology, at the Institute of Biomedical Sciences. She has experience in the area of Cellular and Molecular Biology, with emphasis on Tumor Cell Biology. She contributed to the implementation of short-lived and immortalized cell culture techniques, both in 2D and 3D environments, including prospective, differentiation and cell death, mainly in the evaluation of the anti-cancer therapeutic potential of new compounds of marine origin. She has been dedicated to the study of micronucleus formation controls, to the study of aneuploidy and its significance in the process of tumorigenesis and gene amplification, both in disorders and in polytene chromosomes of Rhynchosciara americana. She dedicated herself to researching relevant aspects in the biology of this organism, focusing on morphological and molecular biology in the salivary gland and ovary. She contributed greatly to the dissemination of confocal laser scanning microscopy in the country, being highly active in this area.