Photon-counting computed tomography (CT) is a new technique that has the potential to revolutionize clinical CT and is predicted to be the next significant advancement. In recent years, tremendous research has been conducted to demonstrate the developments in hardware assembly and its working principles. The articles in this review were obtained by conducting a search of the MEDLINE database. Photon-counting detectors (PCDs) provide excellent quality diagnostic images with high spatial resolution, reduced noise, artifacts, increased contrast-to-noise ratio, and multienergy data acquisition as compared with conventionally used energy-integrating detector (EID). The search covered articles published between 2011 and 2021. The title and abstract of each article were reviewed as determined by the search strategy. From these, eligible studies and articles that provided the working and clinical application of PCDs were selected. This article aims to provide a systematic review of the basic working principles of PCDs, emphasize the uses and clinical applications of PCDs, and compare it to EIDs. It provides a nonmathematical explanation and understanding of photon-counting CT systems for radiologists as well as clinicians.

Magnetic resonance diffusion tensor imaging (DTI) is a recent technique that can measure the direction and magnitude of diffusion of water. It is widely being utilized to evaluate several brain and spinal cord pathologies. The objective of this review is to evaluate the importance of the DTI in patients with spinal cord injury (SCI). It aims to review various articles on DTI SCI and includes both animal and human studies. This will help to describe the current status of the clinical applications of DTI and show its potential as a helpful instrument in clinical practice. The PubMed database was searched for articles relating to the application of DTI in SCI. Relevant articles were also used for the review. A variety of DTI parameters have been studied in various articles. The standard parameters are fractional anisotropy (FA) values, apparent diffusion coefficient (ADC) values, radial diffusivity values, and axial diffusivity values, followed by tractography. FA and ADC values are the most commonly used parameters. The findings observed in most of the studies are increased FA and reduced ADC values following injury to the spinal cord. DTI data metrics possess the potential to become a potent clinical tool in patients with SCI. It is helpful for diagnosis, prognosis, treatment planning, as well as to evaluate the recovery. Nonetheless, to overcome the limitations and determine its reliability clinically, more research has to be performed.

Since the discovery of magnetic resonance imaging (MRI) as an imaging modality, it has evolved immensely and is still doing so. Most imaging modalities have made bedside or emergency imaging possible due to their portability. This aspect is yet to be fully evaluated and established in the case of MRI as its high-field strength requires specialized infrastructure and its time-consuming nature makes its portability questionable. The goal of this review is to access the efficiency and feasibility of low-field portable MRI (pMRI) systems in a wide array of health care applications. Articles from indexed journals, on PubMed, Springer, Elsevier, etc. databases, relevant to this study were searched and reviewed. This review provides an atypical design that could be used in making a pMRI unit that could find its potential in diagnosing a wide variety of pathologies with an added advantage of imaging critical patients in the intensive care unit or patients in isolation due to its portability, imaging patients with implants or prosthesis effectively due to its low field, pediatric imaging due to its high speed, for guided interventions, imaging obese and claustrophobic patients due to its open nature, in dental imaging, extremity scanning, etc. With its vast spectrum of applications in the health care system, the future of low-field pMRI units seems to be bright.

Introduction: Synthetic magnetic resonance imaging (SyMRI) is a non-invasive, robust MRI technique that generates multiple contrast-weighted images by acquiring a single MRI sequence within a few minutes, along with quantitative maps, automatic brain segmentation, and volumetry. Since its inception, it has undergone technical advancements and has also been tested for feasibility in various organs and pathological conditions. This scoping review comprehensively pinpoints the critical technical aspects and maps the wide range of clinical applications/benefits of SyMRI. Content: A comprehensive search was conducted across five databases, PubMed, Scopus, Web of Science, Embase, and CINAHL Ultimate, using appropriate keywords related to SyMRI. A total of 99 studies were included after a 2-step screening process. Data related to the technical factors and clinical application was charted. Summary: SyMRI provides quantitative maps and segmentation techniques comparable to conventional MRI and has demonstrated feasibility and applications across neuroimaging, musculoskeletal, abdominal and breast pathologies spanning the entire human lifespan, from prenatal development to advanced age. Certain drawbacks related to image quality have been encountered that can be overcome with technical advances, especially AI-based algorithms. Outlook: SyMRI has immense potential for being incorporated into routine imaging for various pathologies due to its added advantage of providing quantitative measurements for more robust diagnostic and prognostic work-up with faster acquisitions and greater post-processing options.

Rationale and Objectives Skeleton analysis based on age and gender is of great importance since it is an initial step in personal identification and can be used to rebuild biological profiles and narrow down diagnosis toward correct possibilities of any unknown skeletons. Different dimensions of the maxillary sinus (MS) can be used to differentiate between gender. This study aims to evaluate and compare the dimensions and volume of MS among age and genders. Materials and Methods Ninety patients (male 49, female 41) were studied. Different dimensions of MS, like anteroposterior (AP), superioinferior (SI), mediolateral (ML) diameter, volume of MS, and the distance between two MS were measured on computed tomography (CT) paranasal sinus images using an inbuilt electronic caliper on Digital Imaging and Communications in Medicine viewer software. Statistical Analysis Independent t-test and analysis of variance were used for data analysis in genders and age groups. Paired t-test was used for comparison of right and left MS. Results The dimensions and volume of MS were higher in males than females. Dimensions such as AP, SI diameter (p < 0.005), and volume of MS (p < 0.001) were significantly different in genders. The ML diameter and the distance between two MS were statistically insignificant in genders. No significant difference between MS dimensions and volume was noted in different age groups, but age group 3 (41–55 years) showed higher mean values for all the measurements. A consistency was noted in the measurements in both two-dimensional (2D) and three-dimensional (3D) images. Conclusion MS dimensions are greater in males compared with females. The different dimensions and volumes of the MS using 2D or 3D CT scan images can be used along with other methods for gender determination in forensic anthropology.

Pleural effusion is the fluid collection in the pleural cavity between the parietal and visceral pleura. It is caused by parenchymal diseases such as inflammatory disorders or infection. Pleural effusion can be diagnosed using imaging modalities such as X-ray, computed tomography (CT) scan, ultrasound, and magnetic resonance imaging (MRI).MRI is rarely performed to investigate pleural effusion due to motion artifacts and has a poor spatial resolution. Benign and malignant pleural effusion can be diagnosed using an X-ray, CT scan, or ultrasound. Pleural effusion volume can be measured by using ultrasound. This article reviews the feasibility of investigating pleural effusion and fluid drainage in medical imaging and compares to find the best modality for its diagnosis. Description: This article reports the possible options to detect pleural effusion in medical imaging and compares them to find the best modality for its diagnosis.