Neurodivergent individuals, particularly those on the autism spectrum, often experience support-needs in activities of daily living. This is often due to sensory processing differences that challenge environmental comfort. While technology-based interventions show promise, requirement-driven and accessible solutions for private living settings remain scarce. This project developed a practical guideline that repurposes commercially available smart home technologies to support daily living, environmental comfort, and safety for autistic users and their caregivers. Methods included a literature and technology review focused on sensory stressors (e.g., temperature, noise, light, air quality, movement), synthesis of use cases from two prior human-centered, participatory projects, and iterative refinement via a focus group with experts ( N = 2) and an interview with an adult on the autism spectrum. Technologies were selected for interoperability within mainstream ecosystems and coverage across typical use cases. The resulting guide integrates theoretical foundations with actionable configurations in three domains: General safety (e.g., alarms), structuring daily life (e.g., schedules via voice assistants), and autism-specific supports (e.g., presence sensors). By leveraging off-the-shelf components, the approach reduces cost and barriers to adoption, enhances accessibility, and is suitable for technical novices. This resource aims to improve well-being and autonomy, mitigate caregiver burden, and foster autism-inclusive living environments.