The potential impact of large‐scale climate patterns of El Niño Southern Oscillation (ENSO), North Atlantic Oscillation (NAO) and Pacific Decadal Oscillation (PDO) in modulating precipitation regimes across the upper Medjerda River Basin in northern Tunisia is assessed. As the case study is located in the Mediterranean region (North Africa), the regional Mediterranean Oscillation (MOAC) and Western Mediterranean Oscillation (WeMO) are also investigated. Six precipitation time series are also observed. Strong correlations are identified between ENSO and precipitation series at lag − 2 years. Extreme ENSO years are reflected in the precipitation as periods of severe water deficit or excess. Wavelet spectra driven to seasonal precipitation reveal that precipitation is organized in preferred bands with distinct activities in each scale band, and that most of the precipitation variance is explained by the 2–8‐year scales. Using cross‐wavelet analysis, climate patterns that are most associated with precipitation variability are identified. The analysis demonstrates also that precipitations are simultaneously controlled by different climate patterns. Particularly, the influence of ENSO on precipitation is stronger as well as that of PDO and MO. Results indicate that precipitation variability at the upper Medjerda River Basin is associated with global‐scale ENSO processes at the annual as well as seasonal time scales and is aligned with changing phase difference between periods. Moreover, separation of annual precipitation into two seasons reveals statistically significant associations between El Niño and La Niña phases of ENSO with dry and wet seasonal precipitation, respectively. Complementing this, three streamflow records with length up to 104 years are used, and relationships with rainfall series are analysed using wavelets. A strong coherence between rainfall and streamflow observations is found and justifies undertaking the study of climate‐streamflow relationships where ENSO exhibits potential impacts on annual streamflows. Copyright © 2011 Royal Meteorological Society

The decrease in runoff of the Merguellil basin, Tunisia recorded during the decade 1989–1998 led to the study of several time series derived from daily rainfall. It was found that variability characteristics related to daily rainfall greater than 30 mm are significantly different among successive time periods. In addition, the probability distributions of these rains, recorded at different raingauge sites, are significantly different between the period 1976–1989 and the prior and posterior observation periods. Furthermore, the surface covered by daily rains greater than 30 mm decreased between 1976 and 1989. It was also noted that the probability distributions of the surfaces covered changed significantly after 1976. The combination of human action and pluviometric variability (rainfall increase in the period 1989–1998, notably the increase in the number of days of rainfall greater than 30 mm) may explain the decrease in runoff of Merguellil Wadi.