Skin cancer is one of the widespread diseases among existing cancer types. More importantly, the detection of lesions in early diagnosis has tremendously attracted researchers’ attention. Thus, artificial intelligence (AI)-based techniques have supported the early diagnosis of skin cancer by investigating deep-learning-based convolutional neural networks (CNN). However, the current methods remain challenging in detecting melanoma in dermoscopic images. Therefore, in this paper, we propose an ensemble model that uses the vision of both EfficientNetV2S and Swin-Transformer models to detect the early focal zone of skin cancer. Hence, we considerthat the former architecture leads to greater accuracy, while the latter model has the advantage of recognizing dark parts in an image. We have modified the fifth block of the EfficientNetV2S model and have included the Swin-Transformer model. Our experiments demonstrate that the constructed ensemble model has attained a higher level of accuracy over the individual models and has also decreased the losses as compared to traditional strategies. The proposed model achieved an accuracy score of 99.10%, a sensitivity of 99.27%, and a specificity score of 99.80%.

Leukemia is a deadly disease caused by the overproduction of immature white blood cells (WBS) in the bone marrow. If leukemia is detected at the initial stages, the chances of recovery are better. Typically, morphological analysis for the identification of acute lymphoblastic leukemia (ALL) is performed manually on blood cells by skilled medical personnel, which has several disadvantages, including a lack of medical personnel, sluggish analysis, and prediction that is dependent on the medical personnel’s expertise. Therefore, we proposed the Multi-Attention EfficientNetV2S and EfficientNetB3 state-of-the-art deep learning architectures using transfer learning-based fine-tuning approach to distinguish the normal and blast cells from microscopic blood smear images that both are pretrained on large-scale ImageNet database. We simply modified the last block of both models and added additional layers to both models. After including this Multi-Attention Mechanism, it not only reduces the model’s complexities but also generalizes its network quite well. By using the proposed technique, the accuracy has improved and the overall loss is also minimized. Our Multi-Attention EfficientNetV2S and EfficientNetB3 models achieved 99.73% and 99.25% accuracy, respectively. We have further compared the proposed model’s performance to other individual and ensemble models. Upon comparison, the proposed model outclassed the existing literature and other benchmark models, thus proving its efficiency.