This paper proposes a multiobjective optimization method for signal control design at intersections in urban traffic network. The cell transmission model is employed for macroscopic simulation of the traffic. Additional rules are introduced to model different route choices from origins to destinations. Vehicle turning, merging, and diverging behaviors at intersections are considered. A multiobjective optimization problem (MOP) is formulated considering four measures in network traffic performance, i.e., maximizing system throughputs, minimizing traveling delays, enhancing traffic safety, and avoiding spillovers. The design parameters for an intersection include turning signal type, cycle time, signal offset, and green time in each phase. The resulting high-dimensional MOP is solved with the genetic algorithm (GA). An algorithm is proposed to assist the user to select and implement the optimal designs from the Pareto optimal solution set. A case study in a grid network of nine intersections is carried out to test the optimization algorithm. It is observed that the proposed method is able to achieve the optimal network performance with different traffic demands. The convergence and coefficient selection of GA are discussed. The guidelines for network signal design and operation from the current studies are presented.