Sadaf ul Hassan

Dr. Sadaf ul Hassan


Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
28 September 2021 in Chemical Biology & Drug Design
Verified
Journal Article
Closed access
PDF file
SHSadaf ul Hassan
Sadaf ul Hassan
BBBushra Bilal
Bushra Bilal
MNMuhammad Shahid Nazir
Muhammad Shahid Nazir
SNSyed Ali Raza Naqvi
Syed Ali Raza Naqvi
ZAZufiqar Ali
Zufiqar Ali
AMAysha Mohyuddin
Aysha Mohyuddin

19 January 2023 in Sustainability
Verified
Journal Article
Open access
PDF file
WUWajad Ulfat
Wajad Ulfat
AMAyesha Mohyuddin
Ayesha Mohyuddin
MAMuhammad Amjad
Muhammad Amjad
Tonni Agustiono KurniawanTonni Agustiono Kurniawan
Tonni Agustiono Kurniawan
BMBeenish Mujahid
Beenish Mujahid
MAMuhammad Arif
Muhammad Arif
Air pollution, resulting from buffing dust waste produced by local leather tanning industry, has become a critical issue for the environment and public health. To promote a circular economy through resource recovery, this work developed a thermal insulation composite using buffing dust-laden tanning waste mixed with polystyrene and a blowing agent. To prepare the samples from leather tanning waste, different proportions of buffing dust (5–20% (w/w)) were blended with polystyrene in the presence of 3% (w/w) blowing agent. The composite material was processed in double-barreled with co-twin extruder to expose it to pressure and then heated at 200 °C. Different physico-chemical properties of composite samples were determined. The prepared composite materials had a good thermal conductivity (0.033–0.029 W/m-K), strong compression (5.21–6.25 ton), density (38–20 kg/m3), and water absorption (5–7.5%), as compared to conventional constructional insulation panels. The thermal conductivity of polystyrene was reduced to 10% after the addition of buffing dust (20% w/w). The presence of a blowing agent in the composite material enhanced its volume without compromising its physico-chemical properties. Thermo-gravimetric analysis showed that the thermal stability of the composite material ranged from 200–412 °C. FTIR analysis indicated that the composite had carbonyl and amino functional groups. The SEM images revealed the formation of voids with a decreasing homogeneity of the composite after the addition of the buffing dust waste. The EDX analysis revealed that the composite also had 62% of C and a tiny amount of Cr. This implies that the composite panels can be used for installation in buildings as thermal insulators in the construction sector. Overall, this work not only resolved the energy consumption problems during manufacturing, but it also brought positive impacts on the environment by recycling hazardous buffing dust and then reusing it as a thermal insulation material. Not only does this reduce the air pollution that results from the buffing dust waste, but this also promotes resource recovery in the framework of a circular economy.

19 April 2022 in Frontiers in Chemistry
Verified
Journal Article
Open access
BBBushra Bilal
Bushra Bilal
RNRimsha Niazi
Rimsha Niazi
SNSohail Nadeem
Sohail Nadeem
MFMuhammad Asim Farid
Muhammad Asim Farid
MNMuhammad Shahid Nazir
Muhammad Shahid Nazir
SHSadaf ul Hassan
Sadaf ul Hassan
Periodontal disease is a common complication, and conventional periodontal surgery can lead to severe bleeding. Different membranes have been used for periodontal treatment with limitations, such as improper biodegradation, poor mechanical property, and no effective hemostatic property. Guided tissue regeneration (GTR) membranes favoring periodontal regeneration were prepared to overcome these shortcomings. The mucilage of the chia seed was extracted and utilized to prepare the guided tissue regeneration (GTR) membrane. Lignin having antibacterial properties was used to synthesize lignin-mediated ZnO nanoparticles (∼Lignin@ZnO) followed by characterization with analytical techniques like Fourier-transform infrared spectroscopy (FTIR), UV–visible spectroscopy, and scanning electron microscope (SEM). To fabricate the GTR membrane, extracted mucilage, Lignin@ZnO, and polyvinyl alcohol (PVA) were mixed in different ratios to obtain a thin film. The fabricated GTR membrane was evaluated using a dynamic fatigue analyzer for mechanical properties. Appropriate degradation rates were approved by degradability analysis in water for different intervals of time. The fabricated GTR membrane showed excellent antibacterial properties against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) bacterial species.

11 July 2024 in Frontiers in Chemistry
Verified
Journal Article
Open access
PDF file
ARAisha Rafique
Aisha Rafique
FAFatima Amjad
Fatima Amjad
MJMuhammad Ramzan Saeed Ashraf Janjua
Muhammad Ramzan Saeed Ashraf Janjua
SNSyed Ali Raza Naqvi
Syed Ali Raza Naqvi
SHSadaf ul Hassan
Sadaf ul Hassan
AAAhlam A. Alalwiat
Ahlam A. Alalwiat
Plant extract-mediated fabrication of metal nanocomposites is used in cell proliferation inhibition and topical wound treatment, demonstrating significant effectiveness. Salvia hispanica L. (chia) seed extract (CE) is used as the reaction medium for the green fabrication of ecofriendly ZnO(CE) nanoparticles (NPs) and Ag/Ag2O(CE) and ZnO/Ag/Ag2O(CE) nanocomposites. The resultant nanoparticles and nanocomposite materials were characterized using UV–visible, Fourier-transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), and energy-dispersive X-ray (EDX) techniques. In the context of antioxidant studies, ZnO/Ag/Ag2O(CE) exhibited 57% reducing power and 86% 2,2, diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging. All three materials showed strong antibacterial activity against Staphylococcus aureus (S. aureus), Escherichia coli (E.coli), and Bacillus subtilis (B. subtilis) bacterial strains. Additionally, ZnO(CE), Ag/Ag2O(CE), and ZnO/Ag/Ag2O(CE) also revealed 64.47%, 42.56%, and 75.27% in vitro Michigan Cancer Foundation-7 (MCF7) cancer cell line inhibition, respectively, at a concentration of 100 μg/mL. Selectively, the most effective composite material, ZnO/Ag/Ag2O(CE), was used to evaluate in vivo wound healing potential in rat models. The study revealed 96% wound closure in 10 days, which was quite rapid healing compared to wound healing using clinically available ointment. Therefore, in conclusion, the ZnO/Ag/Ag2O(CE) nanocomposite material could be considered for further testing and formulation as a good anticancer and wound healing agent.

5 August 2025 in International Journal of Biological Macromolecules
Verified
Journal Article
Closed access
RZRehana Zia
Rehana Zia
MNMuhammad Shahid Nazir
Muhammad Shahid Nazir
HRHifza Rouf
Hifza Rouf
NANaveed Ahmad
Naveed Ahmad
FAFarooq Ahmad
Farooq Ahmad
SHSadaf ul Hassan
Sadaf ul Hassan

26 August 2022 in Molecules
Verified
Journal Article
Open access
PDF file
MAMirza Nadeem Ahmad
Mirza Nadeem Ahmad
SNSohail Nadeem
Sohail Nadeem
Mohsin JavedMohsin Javed
Mohsin Javed
Shahid IqbalShahid Iqbal
Shahid Iqbal
SHSadaf ul Hassan
Sadaf ul Hassan
AAAiyeshah Alhodaib
Aiyeshah Alhodaib
The synthesis of MMT and poly(o-anisidine) (MMT/POA) clay nanocomposites was carried out by using the chemical oxidative polymerization of POA and MMT clay with POA, respectively. By maintaining the constant concentration of POA, different percentage loads of MMT clay were used to determine the effect of MMT clay on the properties of POA. The interaction between POA and MMT clay was investigated by FTIR spectroscopy, and, to reveal the complete compactness and homogeneous distribution of MMT clay in POA, were assessed by using scanning-electron-microscope (SEM) analysis. The UV–visible spectrum was studied for the optical and absorbance properties of MMT/POA ceramic nanocomposites. Furthermore, the horizontal burning test (HBT) demonstrated that clay nanofillers inhibit POA combustion.