Alessia Di Girolamo

Dr. Alessia Di Girolamo

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Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 July 2019 in Annals of Vascular Surgery
Verified
Journal Article
Closed access
OMOmbretta Martinelli
Ombretta Martinelli
MFMauro Fresilli
Mauro Fresilli
JJJihad Jabbour
Jihad Jabbour
AGAlessia Di Girolamo
Alessia Di Girolamo
LILuigi Irace
Luigi Irace

14 January 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
FMFrancesca Miceli
Francesca Miceli
ADAda Dajci
Ada Dajci
AGAlessia Di Girolamo
Alessia Di Girolamo
PNPier Giorgio Nardis
Pier Giorgio Nardis
Marta AscioneMarta Ascione
Marta Ascione
WMWassim Mansour
Wassim Mansour
Introduction: A type 2 endoleak (EL2) remains the most prevalent complication of endovascular aortic repair (EVAR) for an abdominal aortic aneurysm (AAA). Methods: We conducted a retrospective, single-center analysis, including patients who underwent embolization for an isolated EL2 after EVAR. The study population was stratified into two groups: Group A, consisting of patients whose EL2 resolved after the first embolization procedure, and Group B, consisting of those with refractory EL2 (rEL2). The indication for EL2 treatment was aneurysmal sac growth amounting to >10 mm from the index EVAR. The indications for endograft explantation were the absence of high comorbidities and persisting aneurysmal sac expansion. Those with high comorbidities were subjected to another endovascular procedure or a conservative approach, the latter being preferred. The primary endpoint was EL2 resolution. The secondary endpoints were mid-term outcomes in terms of aneurysmal sac shrinkage, stability and expansion rates, and aneurysm-related complications. Results: Among 57 patients, 19 patients (33.3%) showed signs of EL2 after the first embolization, whereas 38 (66.6%) presented rEL2. Of these, 14 (36.8%) presented significant aneurysmal sac expansion: 8 patients underwent a secondary embolization, while an open conversion was performed in the remaining 6 patients (42.8%), 4 of whom, in an elective setting, showed a complete resolution of EL2, while 2 patients treated in an urgent setting died from a ruptured aneurysm. Among the patients treated with a secondary embolization, only 2 patients presented EL2 resolution, while the other 6 patients (75%) showed rEL2. Out of the 38 patients with rEL2, 24 patients did not undergo further interventions; of these, 11 (45.8%) presented sac expansion, and 16% developed type IA EL. Conclusions: A strict follow-up and possibly a more aggressive treatment should be considered in an elective setting for patients with rEL2.

19 June 2024 in Diagnostics
Verified
Journal Article
Open access
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WMWassim Mansour
Wassim Mansour
FMFrancesca Miceli
Francesca Miceli
AGAlessia Di Girolamo
Alessia Di Girolamo
ADAda Dajci
Ada Dajci
AMAntonio Marzano
Antonio Marzano
LMLuca Di Marzo
Luca Di Marzo
Introduction: Popliteal artery entrapment syndrome (PAES) is a rare disease of the lower limbs, mainly affecting young patients, due to extrinsic compression of the neurovascular bundle at the popliteal fossa. The aim of this study was to describe our experience during a median 15-year period. Methods: Patients treated for PAES in our institution from 1979 to 2024 were included. Preoperative, intraoperative, and postoperative data were analyzed. Results: A total of 47 patients with a total of 78 limbs were treated. Duplex ultrasound with active maneuvers was performed in all limbs (100%). Angiography was performed in almost all patients (97.4%), computed tomography angiography in 56 (71.8%), and magnetic resonance angiography in 22 (28.2%). Concerning surgical treatment, musculotendinous section was performed in 60 limbs (76.9%), and autologous venous bypass was achieved in 18 limbs (23.1%). The rates for freedom from target lesion revascularization—meaning that no significant stenosis or occlusion during follow-up required revascularization—and 15-year primary patency were 92.4% and 98%, respectively. Conclusion: Long-term results of surgical treatment for PAES seem to be very satisfying. Myotomy with or without arterial reconstruction using venous bypass can lead to good patency at 15 years of follow-up.

31 March 2026 in Journal of Clinical Medicine
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Journal Article
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AMAntonio Marzano
Antonio Marzano
GCGiovanni Gagliardo di Carpinello
Giovanni Gagliardo di Carpinello
AGAlessia Giordano
Alessia Giordano
Rocco CangianoRocco Cangiano
Rocco Cangiano
Marta AscioneMarta Ascione
Marta Ascione
WMWassim Mansour
Wassim Mansour
Zone 2 thoracic endovascular aortic repair (TEVAR) frequently requires left subclavian artery (LSA) preservation to maintain vertebrobasilar and upper-extremity perfusion while obtaining a durable proximal seal. Dedicated single-branch endografts were developed to standardize this step and to facilitate a reproducible fully endovascular strategy. Two main device concepts currently shape this field: integrated unibody branch platforms, represented by Castor and the second-generation Cratos, and modular retrograde-branch systems, represented by the Gore TAG Thoracic Branch Endoprosthesis (TBE). The Castor/Cratos evidence base is broader and older, and is mainly centered on type B aortic dissection, with prospective multicenter and real-world data showing favorable branch patency and aortic remodeling. By contrast, TBE evidence is expanding rapidly and is supported by prospective midterm data in arch aneurysms as well as by increasingly large post-commercial series and comparative analyses across zones 0–2. Beyond outcomes, the two platforms differ substantially in branch directionality, potential contribution to proximal fixation, modularity, branch diameter range, proximal landing requirements, access profile, and regulatory/off-the-shelf availability, all of which have direct consequences for anatomical suitability in dissection, aneurysm disease, and trauma. This narrative review synthesizes current evidence and proposes an anatomy-first, pathology-aware framework for selecting between Castor/Cratos and TBE in totally endovascular zone 2 TEVAR with LSA revascularization.

1 October 2019 in Annals of Vascular Surgery
Verified
Journal Article
Closed access
OMOmbretta Martinelli
Ombretta Martinelli
MFMauro Fresilli
Mauro Fresilli
LILuigi Irace
Luigi Irace
BGBruno Gossetti
Bruno Gossetti
AGAlessia Di Girolamo
Alessia Di Girolamo

14 May 2025 in Annals of Vascular Surgery
Verified
Journal Article
Open access
AGAlessia Di Girolamo
Alessia Di Girolamo
FMFrancesca Miceli
Francesca Miceli
ADAda Dajci
Ada Dajci
RCRocco Cangiano
Rocco Cangiano
MAMarta Ascione
Marta Ascione
WMWassim Mansour
Wassim Mansour
Intravascular ultrasound (IVUS) has numerous applications for the treatment of patients with type B aortic dissections (TBADs). The aim of this study was to analyze the eventual benefits of the use of IVUS in the endovascular treatment of TBAD. Patients who underwent endovascular surgery for TBAD in our department from January 2015 to January 2024 were included in the study. Results for patients who had intraoperative IVUS (group A, 38 patients) were compared with those of patients who had no IVUS (group B, 37 patients). The use of IVUS or not depended on the surgeon's personal choice. Primary outcomes included technical success, defined as correct release into the true lumen, and clinical success. Secondary outcomes were complication rates, reintervention rates, and mortality. The mean follow-up time was 37.5 months (range, 1-108 months). During the analyzed period, 75 patients were treated for TBAD: 19 patients were treated in the acute phase, 41 in the subacute phase and 15 in the chronic phase. Technical success was achieved in 69 patients (92%), with a technical success rate of 100% in group A and of 83.8% in group B (P < 0.0115). Adjunctive intraoperative procedures were required in 6 cases (8%). No intraoperative or 24-hr deaths were recorded. Perioperative aorta-related complications were recorded in 7 cases, and perioperative aorta-related reinterventions were recorded in 6 cases. A 30-day death was recorded in 2 cases. Thirty-day complications were recorded in 4 cases and reinterventions were needed in 5 cases. The results of our study show the importance of IVUS utilization during endovascular treatment of TBAD, including the accurate positioning of the graft, reduced complication, and reintervention rates.