Mechanics-seepage synchronous tests on gas-bearing coal under three different stress paths were designed and implemented to evaluate how load path affected the mechanical strength and permeability of deep mining-disturbed coal. The cracks-count evolution of coal specimens during instability was observed through DEM numerical simulation. The results showed significant stress-strain and strength variations under different paths. At the time of failure, the specimen deformation and peak strength were Test 1 > Test 2 > Test 3, while the permeability was Test 3 > Test 2 > Test 1, with specimen permeability in Test 3 rising prominently. From numerical simulation, the cracks count was Test 2 > Test 3 > Test 1, with tensile cracks taking the largest proportion in Test 2 and shear cracks taking the largest proportion in Test 3. Our findings shed some light on the research and disaster prevention regarding coal and gas outburst.